A4FB64 (A4FB64_SACEN) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Submitted name:
Delta-1-pyrroline-5-carboxylate dehydrogenase EMBL CAM01289.1
EC=1.5.1.12 EMBL CAM01289.1

Gene names

Ordered Locus Names:

SACE_1979

Organism

Saccharopolyspora erythraea (strain NRRL 23338) [Complete proteome] [HAMAP]

Taxonomic identifier

405948 [NCBI]

Taxonomic lineage

Bacteria › Actinobacteria › Actinobacteridae › Actinomycetales › Pseudonocardineae › Pseudonocardiaceae › Saccharopolyspora

Protein attributes

Sequence length	542 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Sequence similarities

Belongs to the aldehyde dehydrogenase family. RuleBase RU003345

Ontologies

Keywords
Molecular function	Oxidoreductase RuleBase RU003344 EMBL CAM01289.1
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	proline biosynthetic process Inferred from electronic annotation. Source: InterPro
Cellular component	mitochondrial matrix Inferred from electronic annotation. Source: InterPro
Molecular function	1-pyrroline-5-carboxylate dehydrogenase activity Inferred from electronic annotation. Source: EC oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor Inferred from electronic annotation. Source: InterPro
Complete GO annotation...

Sequences

	Sequence		Length	Mass (Da)
	A4FB64 [UniParc]. Last modified April 17, 2007. Version 1. Checksum: 9572527E4FF6EF5D	FASTA	542	58,412
	10 20 30 40 50 60 MDAITSVPVP SNEPVKTYAP GSPERESLQK RIAELESERI ELTSTIGGQQ RMAGGERFDV 70 80 90 100 110 120 VQPHKHAHVL GTCAQATHTD VADAVAAAKG AAAEWAATPF DERAAVILRA ADLLAGPWRD 130 140 150 160 170 180 TINGATILGQ SKSVQQAEID AACELIDFLR FNVHYARQIM AEQPNSVPGE WNRMEYRPLD 190 200 210 220 230 240 GFVTAITPFN FTAIAGNLPT APALMGNTVV WKPTPSQQFA AHFTMRLFEA AGMPPGVINM 250 260 270 280 290 300 VTGDGQAVSD IALPDPDMAG LHFTGSTATF KKLWRTIADN LDTYRSYPRI VGETGGKDFI 310 320 330 340 350 360 VVHPSADPAP LATAFVRGAF EYQGQKCSAA SRAYVPRSIW EGGLREQLAE LTRTISYGDV 370 380 390 400 410 420 TDFSHFGGAV IDARAFAKHK AALDRAASTP SIEVLAGGGY DDSVGYFVEP TVLVGTDPTD 430 440 450 460 470 480 EVFTTEYFGP IIAVHVYEDA KYSEILDVVD TSSPYALTGA VFATDRSAID EAHRTLRHAA 490 500 510 520 530 540 GNFYVNDKPT GSIVSRQPFG GSRASGTNDK AGSLFNIQRW TSPRAIKETF NAPTQHTYPH MG

References

[1]

"Complete genome sequence of the erythromycin-producing bacterium Saccharopolyspora erythraea NRRL23338." Oliynyk M., Samborskyy M., Lester J.B., Mironenko T., Scott N., Dickens S., Haydock S.F., Leadlay P.F. Nat. Biotechnol. 25:447-453(2007) [PubMed: 17369815] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].

Cross-references

Sequence databases
EMBL GenBank DDBJ	AM420293 Genomic DNA. Translation: CAM01289.1.
RefSeq	YP_001104214.1. NC_009142.1.
3D structure databases
ProteinModelPortal	A4FB64.
ModBase	Search...
Protein-protein interaction databases
STRING	A4FB64.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
GeneID	4941837.
GenomeReviews	Gene locus SACE_1979 in contig AM420293_GR.
KEGG	sen:SACE_1979.
PATRIC	23411380. VBISacEry28377_1985.
Organism-specific databases
CMR	Search...
Phylogenomic databases
eggNOG	COG1012.
HOGENOM	HBG752218.
OMA	TVVWKPT.
PhylomeDB	A4FB64.
ProtClustDB	CLSK871904.
Enzyme and pathway databases
BioCyc	SERY405948:SACE_1979-MONOMER.
Family and domain databases
InterPro	IPR016161. Ald_DH/histidinol_DH. IPR016163. Ald_DH_C. IPR016160. Ald_DH_CS. IPR016162. Ald_DH_N. IPR015590. Aldehyde_DH_dom. IPR005931. Delta1-pyrroline-5-COlate_DH-1. [Graphical view]
Gene3D	G3DSA:3.40.309.10. Aldehyde_dehydrogenase_C. 1 hit. G3DSA:3.40.605.10. Aldehyde_dehydrogenase_N. 1 hit.
KO	K00294.
Pfam	PF00171. Aldedh. 1 hit. [Graphical view]
SUPFAM	SSF53720. Aldehyde_DH/Histidinol_DH. 1 hit.
TIGRFAMs	TIGR01236. D1pyr5carbox1. 1 hit.
PROSITE	PS00070. ALDEHYDE_DEHYDR_CYS. 1 hit. PS00687. ALDEHYDE_DEHYDR_GLU. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

A4FB64_SACEN

Accession

Primary (citable) accession number: A4FB64

Entry history

Integrated into UniProtKB/TrEMBL:	April 17, 2007
Last sequence update:	April 17, 2007
Last modified:	December 14, 2011
This is version 35 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)