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Protein
Submitted name:

Putative ATP-dependent DNA ligase

Gene

SACE_1861

Organism
Saccharopolyspora erythraea (strain NRRL 23338)
Status
Unreviewed-Annotation score: Annotation score: 1 out of 5-Protein predictedi

Functioni

GO - Molecular functioni

  1. ATP binding Source: InterPro
  2. DNA ligase (ATP) activity Source: UniProtKB-EC

GO - Biological processi

  1. DNA recombination Source: InterPro
  2. DNA repair Source: InterPro
Complete GO annotation...

Keywords - Molecular functioni

LigaseImported

Names & Taxonomyi

Protein namesi
Submitted name:
Putative ATP-dependent DNA ligaseImported (EC:6.5.1.1Imported)
Gene namesi
Ordered Locus Names:SACE_1861Imported
OrganismiSaccharopolyspora erythraea (strain NRRL 23338)Imported
Taxonomic identifieri405948 [NCBI]
Taxonomic lineageiBacteriaActinobacteriaActinobacteridaeActinomycetalesPseudonocardineaePseudonocardiaceaeSaccharopolyspora
ProteomesiUP000006728 Componenti: Chromosome

Interactioni

Protein-protein interaction databases

STRINGi405948.SACE_1861.

Structurei

3D structure databases

ProteinModelPortaliA4FAU8.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Phylogenomic databases

eggNOGiCOG1793.
HOGENOMiHOG000222508.
OMAiNGQFRRW.
OrthoDBiEOG63NMFT.

Family and domain databases

Gene3Di2.40.50.140. 1 hit.
InterProiIPR012309. DNA_ligase_ATP-dep_C.
IPR012310. DNA_ligase_ATP-dep_cent.
IPR012340. NA-bd_OB-fold.
[Graphical view]
PfamiPF04679. DNA_ligase_A_C. 1 hit.
PF01068. DNA_ligase_A_M. 1 hit.
[Graphical view]
SUPFAMiSSF50249. SSF50249. 1 hit.
PROSITEiPS50160. DNA_LIGASE_A3. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

A4FAU8-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MTLPLHPPVK PMLASPVDGV PERAGLFFEP KWDGFRCLVF ADPGAAEPLF
60 70 80 90 100
LQSRTGKSLN RYFPEVLADL GRALTRPAVL DGELVVTRQD EHGDRLDWDA
110 120 130 140 150
LTERIHPAAS RVKLLAERTP ATFIAFDLLA LDDRDLCGEP FSTRRELLSG
160 170 180 190 200
LESDHSGLRT TPATQDHALA GEWFRVFEGA GLDGLIAKDA DGRYEPGKRT
210 220 230 240 250
MLKVKHARTA DCVVAGLRWH ANTEPGTAVG SLLLGLHDDR SVLHHVGVVG
260 270 280 290 300
AFPAARRREL ATSLAPLLSA EDHPWLGPHA EDGRRLPGGV TRWRSGELVW
310 320 330 340 350
EPLRPEKVVE VAYDHTEGAM PSRFRHTTQF VRWRPDRDPE SCRYDQLEEP
360 370
ARYDLDSVLS GTVRAQDAGT
Length:370
Mass (Da):40,996
Last modified:April 16, 2007 - v1
Checksum:iA56C737F4BB56E3B
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AM420293 Genomic DNA. Translation: CAM01173.1.
RefSeqiYP_001104098.1. NC_009142.1.

Genome annotation databases

EnsemblBacteriaiCAM01173; CAM01173; SACE_1861.
GeneIDi4941717.
KEGGisen:SACE_1861.
PATRICi23411138. VBISacEry28377_1868.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AM420293 Genomic DNA. Translation: CAM01173.1.
RefSeqiYP_001104098.1. NC_009142.1.

3D structure databases

ProteinModelPortaliA4FAU8.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi405948.SACE_1861.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiCAM01173; CAM01173; SACE_1861.
GeneIDi4941717.
KEGGisen:SACE_1861.
PATRICi23411138. VBISacEry28377_1868.

Phylogenomic databases

eggNOGiCOG1793.
HOGENOMiHOG000222508.
OMAiNGQFRRW.
OrthoDBiEOG63NMFT.

Family and domain databases

Gene3Di2.40.50.140. 1 hit.
InterProiIPR012309. DNA_ligase_ATP-dep_C.
IPR012310. DNA_ligase_ATP-dep_cent.
IPR012340. NA-bd_OB-fold.
[Graphical view]
PfamiPF04679. DNA_ligase_A_C. 1 hit.
PF01068. DNA_ligase_A_M. 1 hit.
[Graphical view]
SUPFAMiSSF50249. SSF50249. 1 hit.
PROSITEiPS50160. DNA_LIGASE_A3. 1 hit.
[Graphical view]
ProtoNetiSearch...

Publicationsi

  1. "Complete genome sequence of the erythromycin-producing bacterium Saccharopolyspora erythraea NRRL23338."
    Oliynyk M., Samborskyy M., Lester J.B., Mironenko T., Scott N., Dickens S., Haydock S.F., Leadlay P.F.
    Nat. Biotechnol. 25:447-453(2006) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: NRRL 23338Imported.

Entry informationi

Entry nameiA4FAU8_SACEN
AccessioniPrimary (citable) accession number: A4FAU8
Entry historyi
Integrated into UniProtKB/TrEMBL: April 16, 2007
Last sequence update: April 16, 2007
Last modified: March 3, 2015
This is version 46 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported

External Data

Dasty 3

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into Uniref entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.