A4FAI5 (Y1742_SACEN) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
Putative S-adenosyl-L-methionine-dependent methyltransferase SACE_1742
EC=2.1.1.-

Gene names

Ordered Locus Names:

SACE_1742

Organism

Saccharopolyspora erythraea (strain NRRL 23338) [Complete proteome] [HAMAP]

Taxonomic identifier

405948 [NCBI]

Taxonomic lineage

cellular organisms › Bacteria › Actinobacteria › Actinobacteria › Actinobacteridae › Actinomycetales › Pseudonocardineae › Pseudonocardiaceae › Saccharopolyspora › Saccharopolyspora erythraea

Protein attributes

Sequence length	287 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Function	Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity By similarity.
Sequence similarities	Belongs to the UPF0677 family.

Ontologies

Keywords
Ligand	S-adenosyl-L-methionine
Molecular function	Methyltransferase Transferase
Technical term	Complete proteome
Gene Ontology (GO)
Molecular_function	methyltransferase activity Inferred from electronic annotation. Source: UniProtKB-KW
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 287	287	Putative S-adenosyl-L-methionine-dependent methyltransferase SACE_1742		PRO_0000361263
Regions
	Region	148 – 149	2	S-adenosyl-L-methionine binding By similarity
Sites
	Binding site	119	1	S-adenosyl-L-methionine By similarity

Sequences

	Sequence		Length	Mass (Da)
	A4FAI5 [UniParc]. Last modified April 17, 2007. Version 1. Checksum: 147DD46A471DE550	FASTA	287	31,196
	10 20 30 40 50 60 MSANEQWDIV SGVGITALAV AVARARESRR DDRLIDDPYA EPLIRAAQPP VPMSGDGGEA 70 80 90 100 110 120 GALWHEMTDY VSVRSRFFDE WFARACAAGT RQAVVLASGL DTRAFRLEWP EGFRVFEIDQ 130 140 150 160 170 180 PKVLEFKDGT LAAEGVRASC ERHAVAVDLR DDWASALVKA GFDPALPTAW LAEGLLPYLP 190 200 210 220 230 240 PEAEANLLAT VHDLSARGSR IAIESIALAR SALLGADLDD TAREWGIDLK GLFSLEDRPD 250 260 270 280 PGDVLAQRGW RVHRDPVGDL AAGFRRPLSD RAQQLGAAGE MVTAQRD

References

[1]

"Complete genome sequence of the erythromycin-producing bacterium Saccharopolyspora erythraea NRRL23338." Oliynyk M., Samborskyy M., Lester J.B., Mironenko T., Scott N., Dickens S., Haydock S.F., Leadlay P.F. Nat. Biotechnol. 25:447-453(2007) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: NRRL 23338.

Cross-references

Sequence databases
EMBL GenBank DDBJ	AM420293 Genomic DNA. Translation: CAM01060.1.
RefSeq	YP_001103985.1. NC_009142.1.
3D structure databases
ProteinModelPortal	A4FAI5.
ModBase	Search...
Protein-protein interaction databases
STRING	405948.SACE_1742.
Protocols and materials databases
DNASU	4941604.
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
EnsemblBacteria	CAM01060; CAM01060; SACE_1742.
GeneID	4941604.
KEGG	sen:SACE_1742.
PATRIC	23410900. VBISacEry28377_1749.
Organism-specific databases
CMR	Search...
Phylogenomic databases
eggNOG	COG3315.
HOGENOM	HOG000240238.
OMA	FAQITEL.
Family and domain databases
InterPro	IPR011610. CHP00027_methylltransferase. IPR007213. LCM_MeTrfase. [Graphical view]
Pfam	PF04072. LCM. 1 hit. [Graphical view]
TIGRFAMs	TIGR00027. mthyl_TIGR00027. 1 hit.
ProtoNet	Search...

Entry information

Entry name

Y1742_SACEN

Accession

Primary (citable) accession number: A4FAI5

Entry history

Integrated into UniProtKB/Swiss-Prot:	January 20, 2009
Last sequence update:	April 17, 2007
Last modified:	May 1, 2013
This is version 36 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Prokaryotic Protein Annotation Program