A4F8S9 (A4F8S9_SACEN) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Recommended name:
Cytosine-specific methyltransferase RuleBase RU000417
EC=2.1.1.37 RuleBase RU000417

Gene names

Ordered Locus Names:

SACE_1123

Organism

Saccharopolyspora erythraea (strain NRRL 23338) [Complete proteome] [HAMAP]

Taxonomic identifier

405948 [NCBI]

Taxonomic lineage

Bacteria › Actinobacteria › Actinobacteridae › Actinomycetales › Pseudonocardineae › Pseudonocardiaceae › Saccharopolyspora

Protein attributes

Sequence length	248 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Catalytic activity	S-adenosyl-L-methionine + DNA = S-adenosyl-L-homocysteine + DNA containing 5-methylcytosine. RuleBase RU000417
Sequence similarities	Belongs to the C5-methyltransferase family. RuleBase RU000416

Ontologies

Keywords
Biological process	Restriction system RuleBase RU004244
Molecular function	Methyltransferase RuleBase RU000417 EMBL CAM00454.1 Transferase
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	DNA restriction-modification system Inferred from electronic annotation. Source: UniProtKB-KW
Molecular function	DNA (cytosine-5-)-methyltransferase activity Inferred from electronic annotation. Source: EC DNA binding Inferred from electronic annotation. Source: InterPro
Complete GO annotation...

Sequences

	Sequence		Length	Mass (Da)
	A4F8S9 [UniParc]. Last modified April 17, 2007. Version 1. Checksum: 7DB18D07A92626CB	FASTA	248	27,454
	10 20 30 40 50 60 MNPLTVLSLF AGIGGLELGL ERAGMRVVGQ VELDPWCRQV LAHHWPEVPR HDDVRTAVDW 70 80 90 100 110 120 WHSQPRPDVE LVAGGFPCQP FSTYGRRRGI ADERWGWPWM RDVIDAIRPR YVLAENVAAL 130 140 150 160 170 180 LRDTDAFRII LDDLSHLGYL VEWSVVPACS LGAPHTRQRL FVLAHPAGND GQRPLHLPAP 190 200 210 220 230 240 LPPGRPRSGA AGGQTRAERW LPEPDVGRVA HGLPKRLVAS HLRALGNAVV PAVTEHIGRA LLAHTTTR

References

[1]

"Complete genome sequence of the erythromycin-producing bacterium Saccharopolyspora erythraea NRRL23338." Oliynyk M., Samborskyy M., Lester J.B., Mironenko T., Scott N., Dickens S., Haydock S.F., Leadlay P.F. Nat. Biotechnol. 25:447-453(2007) [PubMed: 17369815] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].

Cross-references

Sequence databases
EMBL GenBank DDBJ	AM420293 Genomic DNA. Translation: CAM00454.1.
RefSeq	YP_001103379.1. NC_009142.1.
3D structure databases
ProteinModelPortal	A4F8S9.
ModBase	Search...
Protein-protein interaction databases
STRING	A4F8S9.
Protein family/group databases
REBASE	14900. M.SerORF1123P.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
GeneID	4940981.
GenomeReviews	Gene locus SACE_1123 in contig AM420293_GR.
KEGG	sen:SACE_1123.
Organism-specific databases
CMR	Search...
Phylogenomic databases
eggNOG	COG0270.
HOGENOM	HBG345442.
OMA	EWNCISA.
PhylomeDB	A4F8S9.
ProtClustDB	CLSK967773.
Enzyme and pathway databases
BioCyc	SERY405948:SACE_1123-MONOMER.
Family and domain databases
InterPro	IPR018117. C5_DNA_meth_AS. IPR001525. C5_MeTfrase. [Graphical view]
KO	K00558.
PANTHER	PTHR10629. C5_DNA_meth. 1 hit.
Pfam	PF00145. DNA_methylase. 1 hit. [Graphical view]
PRINTS	PR00105. C5METTRFRASE.
TIGRFAMs	TIGR00675. Dcm. 1 hit.
PROSITE	PS00094. C5_MTASE_1. 1 hit. PS00095. C5_MTASE_2. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

A4F8S9_SACEN

Accession

Primary (citable) accession number: A4F8S9

Entry history

Integrated into UniProtKB/TrEMBL:	April 17, 2007
Last sequence update:	April 17, 2007
Last modified:	November 16, 2011
This is version 29 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)