A4F8R5 (SSRP_SACEN) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
SsrA-binding protein

Gene names

Name:	smpB
Ordered Locus Names:	SACE_1108

Organism

Saccharopolyspora erythraea (strain NRRL 23338) [Complete proteome] [HAMAP]

Taxonomic identifier

405948 [NCBI]

Taxonomic lineage

Bacteria › Actinobacteria › Actinobacteridae › Actinomycetales › Pseudonocardineae › Pseudonocardiaceae › Saccharopolyspora

Protein attributes

Sequence length	158 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Function	Binds specifically to the SsrA RNA (tmRNA) and is required for stable association of SsrA with ribosomes By similarity. HAMAP MF_00023
Subcellular location	Cytoplasm Potential HAMAP MF_00023.
Sequence similarities	Belongs to the SmpB family.

Ontologies

Keywords
Cellular component	Cytoplasm
Ligand	RNA-binding
Technical term	Complete proteome
Gene Ontology (GO)
Cellular component	cytoplasm Inferred from electronic annotation. Source: UniProtKB-SubCell
Molecular function	RNA binding Inferred from electronic annotation. Source: UniProtKB-KW
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 158	158	SsrA-binding protein HAMAP MF_00023		PRO_1000002134

Sequences

	Sequence		Length	Mass (Da)
	A4F8R5 [UniParc]. Last modified April 17, 2007. Version 1. Checksum: 2EF92169CFC42FDC	FASTA	158	18,009
	10 20 30 40 50 60 MAKEQGRKLI AQNRRARHDW SVLDTYETGI VLTGTEVKSL RQGKASLVDG FATVDRGEVW 70 80 90 100 110 120 LRNVHIPEYT EGTWTNHEPR RSRKLLLHKG EIIRLIGKIQ ESGLSLIPLS LYFSDGKAKV 130 140 150 ELALAKGKKA HDKRQDLAKK DAQREIERAM GRARKGKW

References

[1]

"Complete genome sequence of the erythromycin-producing bacterium Saccharopolyspora erythraea NRRL23338." Oliynyk M., Samborskyy M., Lester J.B., Mironenko T., Scott N., Dickens S., Haydock S.F., Leadlay P.F. Nat. Biotechnol. 25:447-453(2007) [PubMed: 17369815] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: NRRL 23338.

Cross-references

Sequence databases
EMBL GenBank DDBJ	AM420293 Genomic DNA. Translation: CAM00440.1.
RefSeq	YP_001103365.1. NC_009142.1.
3D structure databases
ProteinModelPortal	A4F8R5.
SMR	A4F8R5. Positions 8-128.
ModBase	Search...
Protein-protein interaction databases
STRING	A4F8R5.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
GeneID	4940966.
GenomeReviews	Gene locus SACE_1108 in contig AM420293_GR.
KEGG	sen:SACE_1108.
PATRIC	23409600. VBISacEry28377_1114.
Organism-specific databases
CMR	Search...
Phylogenomic databases
eggNOG	COG0691.
HOGENOM	HBG293422.
OMA	EKYEAGI.
ProtClustDB	PRK05422.
Enzyme and pathway databases
BioCyc	SERY405948:SACE_1108-MONOMER.
Family and domain databases
HAMAP	MF_00023. SmpB. [Tree]
InterPro	IPR023620. SmpB. IPR000037. SsrA-bd_prot. IPR020081. SsrA-bd_prot_CS. [Graphical view]
Gene3D	G3DSA:2.40.280.10. SmpB. 1 hit.
KO	K03664.
Pfam	PF01668. SmpB. 1 hit. [Graphical view]
ProDom	PD004488. SmpB. 1 hit. [Graphical view] [Entries sharing at least one domain]
SUPFAM	SSF74982. SmpB. 1 hit.
TIGRFAMs	TIGR00086. SmpB. 1 hit.
PROSITE	PS01317. SSRP. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

SSRP_SACEN

Accession

Primary (citable) accession number: A4F8R5

Entry history

Integrated into UniProtKB/Swiss-Prot:	January 15, 2008
Last sequence update:	April 17, 2007
Last modified:	December 14, 2011
This is version 35 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Prokaryotic Protein Annotation Program