A4F7X6 (A4F7X6_SACEN) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Recommended name:
Peptidyl-tRNA hydrolase HAMAP MF_00083
Short name=PTH HAMAP MF_00083
EC=3.1.1.29 HAMAP MF_00083

Gene names

Name:	pth HAMAP MF_00083 EMBL CAM00150.1
Ordered Locus Names:	SACE_0810

Organism

Saccharopolyspora erythraea (strain NRRL 23338) [Complete proteome] [HAMAP]

Taxonomic identifier

405948 [NCBI]

Taxonomic lineage

Bacteria › Actinobacteria › Actinobacteridae › Actinomycetales › Pseudonocardineae › Pseudonocardiaceae › Saccharopolyspora

Protein attributes

Sequence length	191 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Function	The natural substrate for this enzyme may be peptidyl-tRNAs which drop off the ribosome during protein synthesis By similarity. HAMAP MF_00083
Catalytic activity	N-substituted aminoacyl-tRNA + H2O = N-substituted amino acid + tRNA. HAMAP MF_00083 RuleBase RU000673
Subunit structure	Monomer By similarity. HAMAP MF_00083
Subcellular location	Cytoplasm By similarity HAMAP MF_00083.
Sequence similarities	Belongs to the PTH family. HAMAP MF_00083 RuleBase RU004320

Ontologies

Keywords
Cellular component	Cytoplasm HAMAP MF_00083
Molecular function	Hydrolase HAMAP MF_00083 RuleBase RU000673 EMBL CAM00150.1
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	translation Inferred from electronic annotation. Source: HAMAP
Cellular component	cytoplasm Inferred from electronic annotation. Source: UniProtKB-SubCell
Molecular function	aminoacyl-tRNA hydrolase activity Inferred from electronic annotation. Source: HAMAP
Complete GO annotation...

Sequences

	Sequence		Length	Mass (Da)
	A4F7X6 [UniParc]. Last modified April 17, 2007. Version 1. Checksum: C68D3927A3618993	FASTA	191	20,512
	10 20 30 40 50 60 MSTPEPLALI VGLGNPGPRY EGNRHNIGFL VADELAARVG GKFKAHKSGA EIVEGRLGGV 70 80 90 100 110 120 RAVLAKPRSF MNLSGGPVAG AAKFYKVQPG SLIVIHDELD LPYGTVRLKR GGGENGHNGL 130 140 150 160 170 180 RSISKSLGTK DYLRVRFGID RPPGRMDPAD YVLKDFSGAE RKELAYFVDL CADAVESLAK 190 EGLEAAQNRF H

References

[1]

"Complete genome sequence of the erythromycin-producing bacterium Saccharopolyspora erythraea NRRL23338." Oliynyk M., Samborskyy M., Lester J.B., Mironenko T., Scott N., Dickens S., Haydock S.F., Leadlay P.F. Nat. Biotechnol. 25:447-453(2007) [PubMed: 17369815] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].

Cross-references

Sequence databases
EMBL GenBank DDBJ	AM420293 Genomic DNA. Translation: CAM00150.1.
RefSeq	YP_001103076.1. NC_009142.1.
3D structure databases
ProteinModelPortal	A4F7X6.
SMR	A4F7X6. Positions 5-191.
ModBase	Search...
Protein-protein interaction databases
STRING	A4F7X6.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
GeneID	4940672.
GenomeReviews	Gene locus SACE_0810 in contig AM420293_GR.
KEGG	sen:SACE_0810.
PATRIC	23409004. VBISacEry28377_0820.
Organism-specific databases
CMR	Search...
Phylogenomic databases
eggNOG	COG0193.
HOGENOM	HBG610927.
OMA	IKFKTGG.
PhylomeDB	A4F7X6.
ProtClustDB	CLSK2535940.
Enzyme and pathway databases
BioCyc	SERY405948:SACE_0810-MONOMER.
Family and domain databases
HAMAP	MF_00083. Pept_tRNA_hydro_bact. [Tree]
InterPro	IPR001328. Pept_tRNA_hydro. IPR018171. Pept_tRNA_hydro_CS. [Graphical view]
Gene3D	G3DSA:3.40.50.1470. Pept_tRNA_hydro. 1 hit.
KO	K01056.
PANTHER	PTHR17224. Pept_tRNA_hydro. 1 hit.
Pfam	PF01195. Pept_tRNA_hydro. 1 hit. [Graphical view]
SUPFAM	SSF53178. Pept_tRNA_hydro. 1 hit.
TIGRFAMs	TIGR00447. Pth. 1 hit.
PROSITE	PS01195. PEPT_TRNA_HYDROL_1. 1 hit. PS01196. PEPT_TRNA_HYDROL_2. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

A4F7X6_SACEN

Accession

Primary (citable) accession number: A4F7X6

Entry history

Integrated into UniProtKB/TrEMBL:	April 17, 2007
Last sequence update:	April 17, 2007
Last modified:	December 14, 2011
This is version 38 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)