A4F7V9 (A4F7V9_SACEN) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Recommended name:
Ribosomal RNA small subunit methyltransferase I HAMAP MF_01877
EC=2.1.1.198 HAMAP MF_01877

Alternative name(s):
16S rRNA 2'-O-ribose C1402 methyltransferase HAMAP MF_01877
rRNA (cytidine-2'-O-)-methyltransferase RsmI HAMAP MF_01877

Gene names

Name:	rsmI HAMAP MF_01877
Ordered Locus Names:	SACE_0792

Organism

Saccharopolyspora erythraea (strain NRRL 23338) [Complete proteome] [HAMAP]

Taxonomic identifier

405948 [NCBI]

Taxonomic lineage

Bacteria › Actinobacteria › Actinobacteridae › Actinomycetales › Pseudonocardineae › Pseudonocardiaceae › Saccharopolyspora

Protein attributes

Sequence length	282 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Function	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA By similarity. HAMAP MF_01877
Catalytic activity	S-adenosyl-L-methionine + cytosine(1402) in 16S rRNA = S-adenosyl-L-homocysteine + 2'-O-methylcytosine(1402) in 16S rRNA. HAMAP MF_01877
Subcellular location	Cytoplasm By similarity HAMAP MF_01877.
Sequence similarities	Belongs to the methyltransferase superfamily. RsmI family. HAMAP MF_01877

Ontologies

Keywords
Biological process	rRNA processing HAMAP MF_01877
Cellular component	Cytoplasm HAMAP MF_01877
Ligand	S-adenosyl-L-methionine HAMAP MF_01877
Molecular function	Methyltransferase HAMAP MF_01877 EMBL CAM00133.1 Transferase
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	enzyme-directed rRNA 2'-O-methylation Inferred from electronic annotation. Source: HAMAP
Cellular component	cytoplasm Inferred from electronic annotation. Source: UniProtKB-SubCell
Molecular function	rRNA (cytosine-2'-O-)-methyltransferase activity Inferred from electronic annotation. Source: HAMAP
Complete GO annotation...

Sequences

	Sequence		Length	Mass (Da)
	A4F7V9 [UniParc]. Last modified April 17, 2007. Version 1. Checksum: C0ED3939089AF17D	FASTA	282	29,761
	10 20 30 40 50 60 MDLVAGSGTL LLAATPLGDA RDASARLVDA LGSADVVAAE DTRRVRALAT ALGVTPGGKV 70 80 90 100 110 120 VSYYEAVEAT RTPMLLDELR AGRSVLLVTD AGMPSVSDPG YRLVSACVEE GLAVTCLPGP 130 140 150 160 170 180 SAVTTALAVS GLPSDRFCFE GFPPRKQGER RRWFARLQAE QRTCVFFEAP HRLADALADA 190 200 210 220 230 240 VEVLGGRRPA AVCRELTKTY EEIRRGSLAE LAQWAADGVR GEITVVLGGA APAETSDPAE 250 260 270 280 LVSQVEERAA DGVRLKDAVA EVAEMAGVRK KELYDAVLAA RR

References

[1]

"Complete genome sequence of the erythromycin-producing bacterium Saccharopolyspora erythraea NRRL23338." Oliynyk M., Samborskyy M., Lester J.B., Mironenko T., Scott N., Dickens S., Haydock S.F., Leadlay P.F. Nat. Biotechnol. 25:447-453(2007) [PubMed: 17369815] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].

Cross-references

Sequence databases
EMBL GenBank DDBJ	AM420293 Genomic DNA. Translation: CAM00133.1.
RefSeq	YP_001103059.1. NC_009142.1.
3D structure databases
ProteinModelPortal	A4F7V9.
ModBase	Search...
Protein-protein interaction databases
STRING	A4F7V9.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
GeneID	4940655.
GenomeReviews	Gene locus SACE_0792 in contig AM420293_GR.
KEGG	sen:SACE_0792.
PATRIC	23408968. VBISacEry28377_0802.
Organism-specific databases
CMR	Search...
Phylogenomic databases
eggNOG	COG0313.
HOGENOM	HBG529058.
OMA	IASDRFC.
PhylomeDB	A4F7V9.
Enzyme and pathway databases
BioCyc	SERY405948:SACE_0792-MONOMER.
Family and domain databases
HAMAP	MF_01877. 16SrRNA_methyltr_I. [Tree]
InterPro	IPR000878. 4pyrrol_Mease. IPR014777. 4pyrrole_Mease_sub1. IPR014776. 4pyrrole_Mease_sub2. IPR008189. rRNA_ssu_MeTfrase_I. [Graphical view]
Gene3D	G3DSA:3.40.1010.10. 4pyrrole_Mease_sub1. 1 hit. G3DSA:3.30.950.10. 4pyrrole_Mease_sub2. 1 hit.
KO	K07056.
PANTHER	PTHR21091:SF18. PTHR21091:SF18. 1 hit.
Pfam	PF00590. TP_methylase. 1 hit. [Graphical view]
PIRSF	PIRSF005917. MTase_YraL. 1 hit.
SUPFAM	SSF53790. Cor/por_Metransf. 1 hit.
TIGRFAMs	TIGR00096. TIGR00096. 1 hit.
ProtoNet	Search...

Entry information

Entry name

A4F7V9_SACEN

Accession

Primary (citable) accession number: A4F7V9

Entry history

Integrated into UniProtKB/TrEMBL:	April 17, 2007
Last sequence update:	April 17, 2007
Last modified:	December 14, 2011
This is version 31 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)