ID   A4F6K2_SACEN            Unreviewed;       364 AA.
AC   A4F6K2;
DT   17-APR-2007, integrated into UniProtKB/TrEMBL.
DT   17-APR-2007, sequence version 1.
DT   27-MAR-2024, entry version 100.
DE   SubName: Full=DNA polymerase III beta subunit {ECO:0000313|EMBL:CAL99676.1};
DE            EC=2.7.7.7 {ECO:0000313|EMBL:CAL99676.1};
GN   Name=dnaN {ECO:0000313|EMBL:CAL99676.1};
GN   OrderedLocusNames=SACE_0327 {ECO:0000313|EMBL:CAL99676.1};
OS   Saccharopolyspora erythraea (strain ATCC 11635 / DSM 40517 / JCM 4748 /
OS   NBRC 13426 / NCIMB 8594 / NRRL 2338).
OC   Bacteria; Actinomycetota; Actinomycetes; Pseudonocardiales;
OC   Pseudonocardiaceae; Saccharopolyspora.
OX   NCBI_TaxID=405948 {ECO:0000313|EMBL:CAL99676.1, ECO:0000313|Proteomes:UP000006728};
RN   [1] {ECO:0000313|EMBL:CAL99676.1, ECO:0000313|Proteomes:UP000006728}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 11635 / DSM 40517 / JCM 4748 / NBRC 13426 / NCIMB 8594 /
RC   NRRL 2338 {ECO:0000313|Proteomes:UP000006728};
RX   PubMed=17369815; DOI=10.1038/nbt1297;
RA   Oliynyk M., Samborskyy M., Lester J.B., Mironenko T., Scott N., Dickens S.,
RA   Haydock S.F., Leadlay P.F.;
RT   "Complete genome sequence of the erythromycin-producing bacterium
RT   Saccharopolyspora erythraea NRRL23338.";
RL   Nat. Biotechnol. 25:447-453(2007).
CC   -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000256|ARBA:ARBA00004496}.
CC   -!- SIMILARITY: Belongs to the beta sliding clamp family.
CC       {ECO:0000256|ARBA:ARBA00010752}.
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DR   EMBL; AM420293; CAL99676.1; -; Genomic_DNA.
DR   RefSeq; WP_009946918.1; NZ_PDBV01000001.1.
DR   AlphaFoldDB; A4F6K2; -.
DR   STRING; 405948.SACE_0327; -.
DR   KEGG; sen:SACE_0327; -.
DR   eggNOG; COG0592; Bacteria.
DR   HOGENOM; CLU_038149_1_0_11; -.
DR   OrthoDB; 4337829at2; -.
DR   Proteomes; UP000006728; Chromosome.
DR   GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR   GO; GO:0009360; C:DNA polymerase III complex; IEA:InterPro.
DR   GO; GO:0008408; F:3'-5' exonuclease activity; IEA:InterPro.
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0003887; F:DNA-directed DNA polymerase activity; IEA:UniProtKB-KW.
DR   GO; GO:0006260; P:DNA replication; IEA:UniProtKB-KW.
DR   CDD; cd00140; beta_clamp; 1.
DR   Gene3D; 3.10.150.10; DNA Polymerase III, subunit A, domain 2; 3.
DR   InterPro; IPR046938; DNA_clamp_sf.
DR   InterPro; IPR001001; DNA_polIII_beta.
DR   InterPro; IPR022635; DNA_polIII_beta_C.
DR   InterPro; IPR022637; DNA_polIII_beta_cen.
DR   InterPro; IPR022634; DNA_polIII_beta_N.
DR   NCBIfam; TIGR00663; dnan; 1.
DR   PANTHER; PTHR30478:SF0; BETA SLIDING CLAMP; 1.
DR   PANTHER; PTHR30478; DNA POLYMERASE III SUBUNIT BETA; 1.
DR   Pfam; PF00712; DNA_pol3_beta; 1.
DR   Pfam; PF02767; DNA_pol3_beta_2; 1.
DR   Pfam; PF02768; DNA_pol3_beta_3; 1.
DR   SMART; SM00480; POL3Bc; 1.
DR   SUPFAM; SSF55979; DNA clamp; 3.
PE   3: Inferred from homology;
KW   Cytoplasm {ECO:0000256|ARBA:ARBA00022490};
KW   DNA replication {ECO:0000256|ARBA:ARBA00022705};
KW   DNA-directed DNA polymerase {ECO:0000256|ARBA:ARBA00022932};
KW   Nucleotidyltransferase {ECO:0000256|ARBA:ARBA00022695,
KW   ECO:0000313|EMBL:CAL99676.1};
KW   Reference proteome {ECO:0000313|Proteomes:UP000006728};
KW   Transferase {ECO:0000256|ARBA:ARBA00022679, ECO:0000313|EMBL:CAL99676.1}.
FT   DOMAIN          9..117
FT                   /note="DNA polymerase III beta sliding clamp N-terminal"
FT                   /evidence="ECO:0000259|Pfam:PF00712"
FT   DOMAIN          136..239
FT                   /note="DNA polymerase III beta sliding clamp central"
FT                   /evidence="ECO:0000259|Pfam:PF02767"
FT   DOMAIN          248..363
FT                   /note="DNA polymerase III beta sliding clamp C-terminal"
FT                   /evidence="ECO:0000259|Pfam:PF02768"
SQ   SEQUENCE   364 AA;  38719 MW;  51285AEF90E99F05 CRC64;
     MDLDVTAPTR ALAAAAADLV RLLPGRLLDP VLAGMVLTAT PQGLELAGTD RERGIRLSRR
     ARTHAEGRIL VPARPLAETL RNLDSVEVRL VVEGAKLALR TRNARFALPL LDLAAHPGVR
     AAPPRAGALD AALLPAVAVV AAATSRDDAL PVFTGVHVKQ RGERLVLAGT DRFRMAVATL
     PWRPGTDDLD VLVPSGLLTE VAKQASGDEV MLRADADRVG LSWADAEVST TLLDAPFPDE
     SRHLLPEVDC AVEVRADEVA GAVRRVSPYA GAHGAVVLDV GDAEVRVRAA DPQFGDAQEA
     VKATVTGDRF SPAFQPRYLA DALQAFAGRT VRMGLRSGLR RSTVISDVDA PEADLRYVLM
     PKRI
//