A4F695 (A4F695_SACEN) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Recommended name:
Putative phenylalanine aminotransferase HAMAP MF_01513
EC=2.6.1.- HAMAP MF_01513

Gene names

Name:	hisC2 EMBL CAL99569.1
Synonyms:	pat HAMAP MF_01513
Ordered Locus Names:	SACE_0217

Organism

Saccharopolyspora erythraea (strain NRRL 23338) [Complete proteome] [HAMAP]

Taxonomic identifier

405948 [NCBI]

Taxonomic lineage

Bacteria › Actinobacteria › Actinobacteridae › Actinomycetales › Pseudonocardineae › Pseudonocardiaceae › Saccharopolyspora

Protein attributes

Sequence length	350 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Function	May catalyze the transamination reaction in phenylalanine biosynthesis By similarity. HAMAP MF_01513
Cofactor	Pyridoxal phosphate By similarity. HAMAP MF_01513 SAAS SAAS005861
Sequence similarities	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. HAMAP MF_01513

Ontologies

Keywords
Ligand	Pyridoxal phosphate HAMAP MF_01513 SAAS SAAS005861
Molecular function	Aminotransferase HAMAP MF_01513 SAAS SAAS005861 EMBL CAL99569.1 Transferase
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	histidine biosynthetic process Inferred from electronic annotation. Source: InterPro
Molecular function	L-phenylalanine:2-oxoglutarate aminotransferase activity Inferred from electronic annotation. Source: EC histidinol-phosphate transaminase activity Inferred from electronic annotation. Source: EC pyridoxal phosphate binding Inferred from electronic annotation. Source: InterPro
Complete GO annotation...

Sequences

	Sequence		Length	Mass (Da)
	A4F695 [UniParc]. Last modified April 17, 2007. Version 1. Checksum: 778A07E4018C6CA0	FASTA	350	38,108
	10 20 30 40 50 60 MTVRTRADLD QLPAYVAGRT VPGSIKLASN EVSAGPLPSV VETITRAAAE VHRYPDMGAT 70 80 90 100 110 120 KLTEALADKL HVAPERLAVG CGSVALCEQL VQATCSAEDE VVYPWRSFEA YPIITRVVGA 130 140 150 160 170 180 RQIPVPLTGE HALDLDAMAS AITSRTRLVF VCSPNNPTGP LVRRAELEAF LDRVPSDVLV 190 200 210 220 230 240 VLDEAYWEFV SDPEAPDGVE VARARENVAS MRTFSKAYGL AGLRVGYTYA PEHVAAALRK 250 260 270 280 290 300 VCIPFSVNAV AQAAAVASLE AQDELKERCD SVVSERRRVR DELLGLGYEV PETQANFVWL 310 320 330 340 350 PLGESTQEFN EHCLDNRVVV RAFVGEGARV TIGRPEENDT FLAAARSYRR

References

[1]

"Complete genome sequence of the erythromycin-producing bacterium Saccharopolyspora erythraea NRRL23338." Oliynyk M., Samborskyy M., Lester J.B., Mironenko T., Scott N., Dickens S., Haydock S.F., Leadlay P.F. Nat. Biotechnol. 25:447-453(2007) [PubMed: 17369815] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].

Cross-references

Sequence databases
EMBL GenBank DDBJ	AM420293 Genomic DNA. Translation: CAL99569.1.
RefSeq	YP_001102495.1. NC_009142.1.
3D structure databases
ProteinModelPortal	A4F695.
ModBase	Search...
Protein-protein interaction databases
STRING	A4F695.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
GeneID	4940082.
GenomeReviews	Gene locus SACE_0217 in contig AM420293_GR.
KEGG	sen:SACE_0217.
PATRIC	23407784. VBISacEry28377_0219.
Organism-specific databases
CMR	Search...
Phylogenomic databases
eggNOG	COG0079.
HOGENOM	HBG646350.
OMA	NNTKIVW.
ProtClustDB	CLSK2535815.
Enzyme and pathway databases
BioCyc	SERY405948:SACE_0217-MONOMER.
Family and domain databases
HAMAP	MF_01023. HisC_aminotrans_2. [Tree] MF_01513. Phe_aminotrans_2. [Tree]
InterPro	IPR001917. Aminotrans_II_pyridoxalP_BS. IPR004839. Aminotransferase_I/II. IPR024892. AroT. IPR005861. HisP_aminotrans. IPR015424. PyrdxlP-dep_Trfase_major_dom. IPR015421. PyrdxlP-dep_Trfase_major_sub1. IPR015422. PyrdxlP-dep_Trfase_major_sub2. [Graphical view]
Gene3D	G3DSA:3.40.640.10. PyrdxlP-dep_Trfase_major_sub1. 1 hit. G3DSA:3.90.1150.10. PyrdxlP-dep_Trfase_major_sub2. 1 hit.
KO	K00817.
Pfam	PF00155. Aminotran_1_2. 1 hit. [Graphical view]
SUPFAM	SSF53383. PyrdxlP-dep_Trfase_major. 1 hit.
TIGRFAMs	TIGR01141. HisC. 1 hit.
PROSITE	PS00599. AA_TRANSFER_CLASS_2. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

A4F695_SACEN

Accession

Primary (citable) accession number: A4F695

Entry history

Integrated into UniProtKB/TrEMBL:	April 17, 2007
Last sequence update:	April 17, 2007
Last modified:	January 25, 2012
This is version 35 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)