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Protein
Submitted name:

Immunoblobulin G1 Fab heavy chain variable region

Gene

VHCH1

Organism
Homo sapiens (Human)
Status
Unreviewed-Annotation score: Annotation score: 1 out of 5-Experimental evidence at protein leveli

Functioni

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Binding sitei208N-acetyl-D-glucosamineCombined sources1

Names & Taxonomyi

Protein namesi
Submitted name:
Immunoblobulin G1 Fab heavy chain variable regionImported
Gene namesi
Name:VHCH1Imported
OrganismiHomo sapiens (Human)Imported
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo

PTM / Processingi

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Disulfide bondi19 ↔ 93Combined sources
Disulfide bondi154 ↔ 210Combined sources

Proteomic databases

MaxQBiA4F255.
PeptideAtlasiA4F255.
PRIDEiA4F255.

Structurei

3D structure databases

Select the link destinations:
PDBei
RCSB PDBi
PDBji
Links Updated
PDB entryMethodResolution (Å)ChainPositionsPDBsum
2QADX-ray3.30D/H1-228[»]
ProteinModelPortaliA4F255.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini1 – 93Ig-likeInterPro annotationAdd BLAST93
Domaini133 – 226Ig-likeInterPro annotationAdd BLAST94

Phylogenomic databases

HOVERGENiHBG005814.

Family and domain databases

Gene3Di2.60.40.10. 2 hits.
InterProiView protein in InterPro
IPR007110. Ig-like_dom.
IPR036179. Ig-like_dom_sf.
IPR013783. Ig-like_fold.
IPR003006. Ig/MHC_CS.
IPR003597. Ig_C1-set.
IPR003599. Ig_sub.
IPR013106. Ig_V-set.
PfamiView protein in Pfam
PF07654. C1-set. 1 hit.
PF07686. V-set. 1 hit.
SMARTiView protein in SMART
SM00409. IG. 1 hit.
SM00407. IGc1. 1 hit.
SM00406. IGv. 1 hit.
SUPFAMiSSF48726. SSF48726. 2 hits.
PROSITEiView protein in PROSITE
PS50835. IG_LIKE. 2 hits.
PS00290. IG_MHC. 1 hit.

Sequencei

Sequence statusi: Fragment.

A4F255-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
LEESGGGVVQ PGKSLRLSCT ASGFIFSDFG MHWVRQAPGK GLESVATIWS
60 70 80 90 100
DGSNEKYADS VTGRFAISRD NSKNMLYLHM DNLRAEDTAV YYCARDADMI
110 120 130 140 150
TFARILDPPF HKGMDVWGQG TTVIVSSAST KGPSVFPLAP SSKSTSGGTA
160 170 180 190 200
ALGCLVKDYF PEPVTVSWNS GALTSGVHTF PAVLQSSGLY SLSSVVTVPS
210 220 230
SSLGTQTYIC NVNHKPSNTK VDKKVEPKSC DKTS
Length:234
Mass (Da):24,904
Last modified:April 17, 2007 - v1
Checksum:i5B93F757FF3FFADA
GO

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Non-terminal residuei1Imported1
Non-terminal residuei234Imported1

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AB274410 mRNA. Translation: BAF48997.1.

Similar proteinsi

Entry informationi

Entry nameiA4F255_HUMAN
AccessioniPrimary (citable) accession number: A4F255
Entry historyiIntegrated into UniProtKB/TrEMBL: April 17, 2007
Last sequence update: April 17, 2007
Last modified: October 25, 2017
This is version 47 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Miscellaneousi

Keywords - Technical termi

3D-structureCombined sources