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Protein
Submitted name:

Ras-related C3 botulinum toxin substrate 1 (Rho family, small GTP binding protein Rac1)

Gene

RAC1

Organism
Homo sapiens (Human)
Status
Unreviewed-Annotation score: Annotation score: 1 out of 5-Protein inferred from homologyi

Functioni

GO - Molecular functioni

GO - Biological processi

Keywordsi

LigandGTP-bindingSAAS annotation, Nucleotide-binding

Names & Taxonomyi

Protein namesi
Submitted name:
Ras-related C3 botulinum toxin substrate 1 (Rho family, small GTP binding protein Rac1)Imported
Submitted name:
Ras-related C3 botulinum toxin substrate 1 (Rho family, small GTP binding protein Rac1), isoform CRA_bImported
Gene namesi
Name:RAC1Imported
ORF Names:hCG_14926Imported, tcag7.839Imported
OrganismiHomo sapiens (Human)
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo

Subcellular locationi

GO - Cellular componenti

Keywords - Cellular componenti

MembraneSAAS annotation

Expressioni

Gene expression databases

BgeeiENSG00000136238.

Family & Domainsi

Sequence similaritiesi

Belongs to the small GTPase superfamily. Rho family.SAAS annotation

Phylogenomic databases

HOGENOMiHOG000233974.
HOVERGENiHBG009351.

Family and domain databases

InterProiView protein in InterPro
IPR027417. P-loop_NTPase.
IPR005225. Small_GTP-bd_dom.
IPR001806. Small_GTPase.
IPR003578. Small_GTPase_Rho.
PfamiView protein in Pfam
PF00071. Ras. 1 hit.
SUPFAMiSSF52540. SSF52540. 1 hit.
TIGRFAMsiTIGR00231. small_GTP. 1 hit.
PROSITEiView protein in PROSITE
PS51420. RHO. 1 hit.

Sequencei

Sequence statusi: Complete.

A4D2P2-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MVDGKPVNLG LWDTAGQEDY DRLRPLSYPQ TDVFLICFSL VSPASFENVR
60 70 80 90 100
AKWYPEVRHH CPNTPIILVG TKLDLRDDKD TIEKLKEKKL TPITYPQGLA
110 120 130 140
MAKEIGAVKY LECSALTQRG LKTVFDEAIR AVLCPPPVKK RKRKCLLL
Length:148
Mass (Da):16,797
Last modified:April 3, 2007 - v1
Checksum:i3E45B67795ABB44C
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CH236963 Genomic DNA. Translation: EAL23720.1.
CH878731 Genomic DNA. Translation: EAW55040.1.
CH878731 Genomic DNA. Translation: EAW55042.1.
UniGeneiHs.413812.

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.

Entry informationi

Entry nameiA4D2P2_HUMAN
AccessioniPrimary (citable) accession number: A4D2P2
Entry historyiIntegrated into UniProtKB/TrEMBL: April 3, 2007
Last sequence update: April 3, 2007
Last modified: May 10, 2017
This is version 89 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.