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Protein
Submitted name:

Ras-related C3 botulinum toxin substrate 1 (Rho family, small GTP binding protein Rac1)

Gene

RAC1

Organism
Homo sapiens (Human)
Status
Unreviewed-Annotation score: Annotation score: 1 out of 5-Experimental evidence at transcript leveli

Functioni

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Names & Taxonomyi

Protein namesi
Submitted name:
Ras-related C3 botulinum toxin substrate 1 (Rho family, small GTP binding protein Rac1)Imported
Submitted name:
Ras-related C3 botulinum toxin substrate 1 (Rho family, small GTP binding protein Rac1), isoform CRA_aImported
Submitted name:
Ras-related C3 botulinum toxin substrate 1 isoform Rac1Imported
Submitted name:
cDNA FLJ30431 fis, clone BRACE2008968, highly similar to Ras-related C3 botulinum toxin substrate 1Imported
Submitted name:
cDNA FLJ75553, highly similar to Homo sapiens ras-related C3 botulinum toxin substrate 1 (rho family, small GTP binding protein Rac1) (RAC1), transcript variant Rac1, mRNAImported
Gene namesi
Name:RAC1Imported
ORF Names:hCG_14926Imported, tcag7.839Imported
OrganismiHomo sapiens (Human)
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo

Subcellular locationi

GO - Cellular componenti

Complete GO annotation...

Pathology & Biotechi

Organism-specific databases

PharmGKBiPA34162.

Expressioni

Gene expression databases

BgeeiENSG00000136238.

Structurei

3D structure databases

SMRiA4D2P1. Positions 1-177.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Phylogenomic databases

HOVERGENiHBG009351.
KOiK04392.
PhylomeDBiA4D2P1.

Family and domain databases

Gene3Di3.40.50.300. 1 hit.
InterProiIPR027417. P-loop_NTPase.
IPR005225. Small_GTP-bd_dom.
IPR001806. Small_GTPase.
[Graphical view]
PfamiPF00071. Ras. 1 hit.
[Graphical view]
SUPFAMiSSF52540. SSF52540. 1 hit.
TIGRFAMsiTIGR00231. small_GTP. 1 hit.

Sequencei

Sequence statusi: Complete.

A4D2P1-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MQAIKCVVVG DGAVGKTCLL ISYTTNAFPG EYIPTVFDNY SANVMVDGKP
60 70 80 90 100
VNLGLWDTAG QEDYDRLRPL SYPQTDVFLI CFSLVSPASF ENVRAKWYPE
110 120 130 140 150
VRHHCPNTPI ILVGTKLDLR DDKDTIEKLK EKKLTPITYP QGLAMAKEIG
160 170 180 190
AVKYLECSAL TQRGLKTVFD EAIRAVLCPP PVKKRKRKCL LL
Length:192
Mass (Da):21,450
Last modified:April 3, 2007 - v1
Checksum:iACEDF83A45E5EA67
GO

Experimental Info

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Non-terminal residuei192 – 1921Imported

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AK291806 mRNA. Translation: BAF84495.1.
AK054993 mRNA. Translation: BAG51447.1.
AB451238 mRNA. Translation: BAG70052.1.
AB451363 mRNA. Translation: BAG70177.1.
CH236963 Genomic DNA. Translation: EAL23719.1.
CH878731 Genomic DNA. Translation: EAW55039.1.
RefSeqiNP_008839.2. NM_006908.4.
UniGeneiHs.413812.

Genome annotation databases

GeneIDi5879.
KEGGihsa:5879.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AK291806 mRNA. Translation: BAF84495.1.
AK054993 mRNA. Translation: BAG51447.1.
AB451238 mRNA. Translation: BAG70052.1.
AB451363 mRNA. Translation: BAG70177.1.
CH236963 Genomic DNA. Translation: EAL23719.1.
CH878731 Genomic DNA. Translation: EAW55039.1.
RefSeqiNP_008839.2. NM_006908.4.
UniGeneiHs.413812.

3D structure databases

SMRiA4D2P1. Positions 1-177.
ModBaseiSearch...
MobiDBiSearch...

Protocols and materials databases

DNASUi5879.
Structural Biology KnowledgebaseSearch...

Genome annotation databases

GeneIDi5879.
KEGGihsa:5879.

Organism-specific databases

CTDi5879.
PharmGKBiPA34162.

Phylogenomic databases

HOVERGENiHBG009351.
KOiK04392.
PhylomeDBiA4D2P1.

Miscellaneous databases

ChiTaRSiRAC1. human.
GenomeRNAii5879.

Gene expression databases

BgeeiENSG00000136238.

Family and domain databases

Gene3Di3.40.50.300. 1 hit.
InterProiIPR027417. P-loop_NTPase.
IPR005225. Small_GTP-bd_dom.
IPR001806. Small_GTPase.
[Graphical view]
PfamiPF00071. Ras. 1 hit.
[Graphical view]
SUPFAMiSSF52540. SSF52540. 1 hit.
TIGRFAMsiTIGR00231. small_GTP. 1 hit.
ProtoNetiSearch...

Entry informationi

Entry nameiA4D2P1_HUMAN
AccessioniPrimary (citable) accession number: A4D2P1
Entry historyi
Integrated into UniProtKB/TrEMBL: April 3, 2007
Last sequence update: April 3, 2007
Last modified: September 7, 2016
This is version 90 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.