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Protein
Submitted name:

TAF6 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 80kDa

Gene

TAF6

Organism
Homo sapiens (Human)
Status
Unreviewed-Annotation score: Annotation score: 2 out of 5-Protein predictedi

Functioni

GO - Molecular functioni

  1. DNA binding Source: Ensembl

GO - Biological processi

  1. DNA-templated transcription, initiation Source: InterPro
  2. regulation of sequence-specific DNA binding transcription factor activity Source: InterPro
Complete GO annotation...

Names & Taxonomyi

Protein namesi
Submitted name:
TAF6 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 80kDaImported
Gene namesi
Name:TAF6Imported
ORF Names:tcag7.663Imported
OrganismiHomo sapiens (Human)Imported
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo

Subcellular locationi

GO - Cellular componenti

  1. cytoplasm Source: HPA
  2. nucleus Source: HPA
Complete GO annotation...

PTM / Processingi

Proteomic databases

PRIDEiA4D299.

Expressioni

Gene expression databases

BgeeiA4D299.
ExpressionAtlasiA4D299. baseline and differential.

Structurei

3D structure databases

ProteinModelPortaliA4D299.
SMRiA4D299. Positions 9-66.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Phylogenomic databases

HOGENOMiHOG000253001.
HOVERGENiHBG012489.
KOiK03131.

Family and domain databases

Gene3Di1.10.20.10. 1 hit.
InterProiIPR016024. ARM-type_fold.
IPR011442. DUF1546.
IPR009072. Histone-fold.
IPR004823. TAF_TATA-bd.
[Graphical view]
PfamiPF07571. DUF1546. 1 hit.
PF02969. TAF. 1 hit.
[Graphical view]
SMARTiSM00803. TAF. 1 hit.
[Graphical view]
SUPFAMiSSF47113. SSF47113. 1 hit.
SSF48371. SSF48371. 1 hit.

Sequencei

Sequence statusi: Complete.

A4D299-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MAEEKKLKLS NTVLPSESMK VVAESMGIAQ IQEETCQLLT DEDALKFMHM
60 70 80 90 100
GKRQKLTTSD IDYALKLKNV EPLYGFHAQE FIPFRFASGG GRELYFYEEK
110 120 130 140 150
EVDLSDIINT PLPRVPLDVC LKAHWLSIEG CQPAIPENPP PAPKEQQKAE
160 170 180 190 200
ATEPLKSAKP GQEEDGPLKG KGQGATTADG KGKEKKAPPL LEGAPLRLKP
210 220 230 240 250
RSIHELSVEQ QLYYKEITEA CVGSCEAKRA EALQSIATDP GLYQMLPRFS
260 270 280 290 300
TFISEGVRVN VVQNNLALLI YLMRMVKALM DNPTLYLEKY VHELIPAVMT
310 320 330 340 350
CIVSRQLCLR PDVDNHWALR DFAARLVAQI CKHFSTTTNN IQSRITKTFT
360 370 380 390 400
KSWVDEKTPW TTRYGSIAGL AELGHDVIKT LILPRLQQEG ERIRSVLDGP
410 420 430 440 450
VLSNIDRIGA DHVQSLLLKH CAPVLAKLRP PPDNQDAYRA EFGSLGPLLC
460 470 480 490 500
SQVVKARAQA ALQAQQVNRT TLTITQPRPT LTLSQAPQPG PRTPGLLKVP
510 520 530 540 550
GSIALPVQTL VSARAAAPPQ PSPPPTKFIV MSSSSSAPST QQVLSLSTSA
560 570 580 590 600
PGSGSTTTSP VTTTVPSVQP IVKLVSTATT APPSTAPSGP GSVQKYIVVS
610 620 630 640 650
LPPTGEGKGG PTSHPSPVPP PASSPSPLSG SALCGGKQEA GDSPPPAPGT
660
PKANGSQPNS GSPQPAP
Length:667
Mass (Da):71,480
Last modified:April 3, 2007 - v1
Checksum:i7913E23A05CFA39C
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CH236956 Genomic DNA. Translation: EAL23853.1.
RefSeqiXP_006716164.1. XM_006716101.1.
XP_006716165.1. XM_006716102.1.
UniGeneiHs.489309.

Genome annotation databases

GeneIDi6878.
KEGGihsa:6878.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CH236956 Genomic DNA. Translation: EAL23853.1.
RefSeqiXP_006716164.1. XM_006716101.1.
XP_006716165.1. XM_006716102.1.
UniGeneiHs.489309.

3D structure databases

ProteinModelPortaliA4D299.
SMRiA4D299. Positions 9-66.
ModBaseiSearch...
MobiDBiSearch...

Proteomic databases

PRIDEiA4D299.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

GeneIDi6878.
KEGGihsa:6878.

Organism-specific databases

CTDi6878.

Phylogenomic databases

HOGENOMiHOG000253001.
HOVERGENiHBG012489.
KOiK03131.

Miscellaneous databases

ChiTaRSiTAF6. human.
GenomeRNAii6878.
NextBioi27032783.

Gene expression databases

BgeeiA4D299.
ExpressionAtlasiA4D299. baseline and differential.

Family and domain databases

Gene3Di1.10.20.10. 1 hit.
InterProiIPR016024. ARM-type_fold.
IPR011442. DUF1546.
IPR009072. Histone-fold.
IPR004823. TAF_TATA-bd.
[Graphical view]
PfamiPF07571. DUF1546. 1 hit.
PF02969. TAF. 1 hit.
[Graphical view]
SMARTiSM00803. TAF. 1 hit.
[Graphical view]
SUPFAMiSSF47113. SSF47113. 1 hit.
SSF48371. SSF48371. 1 hit.
ProtoNetiSearch...

Publicationsi

  1. "Human chromosome 7: DNA sequence and biology."
    Scherer S.W., Cheung J., MacDonald J.R., Osborne L.R., Nakabayashi K., Herbrick J.A., Carson A.R., Parker-Katiraee L., Skaug J., Khaja R., Zhang J., Hudek A.K., Li M., Haddad M., Duggan G.E., Fernandez B.A., Kanematsu E., Gentles S.
    , Christopoulos C.C., Choufani S., Kwasnicka D., Zheng X.H., Lai Z., Nusskern D., Zhang Q., Gu Z., Lu F., Zeesman S., Nowaczyk M.J., Teshima I., Chitayat D., Shuman C., Weksberg R., Zackai E.H., Grebe T.A., Cox S.R., Kirkpatrick S.J., Rahman N., Friedman J.M., Heng H.H., Pelicci P.G., Lo-Coco F., Belloni E., Shaffer L.G., Pober B., Morton C.C., Gusella J.F., Bruns G.A., Korf B.R., Quade B.J., Ligon A.H., Ferguson H., Higgins A.W., Leach N.T., Herrick S.R., Lemyre E., Farra C.G., Kim H.G., Summers A.M., Gripp K.W., Roberts W., Szatmari P., Winsor E.J., Grzeschik K.H., Teebi A., Minassian B.A., Kere J., Armengol L., Pujana M.A., Estivill X., Wilson M.D., Koop B.F., Tosi S., Moore G.E., Boright A.P., Zlotorynski E., Kerem B., Kroisel P.M., Petek E., Oscier D.G., Mould S.J., Dohner H., Dohner K., Rommens J.M., Vincent J.B., Venter J.C., Li P.W., Mural R.J., Adams M.D., Tsui L.C.
    Science 300:767-772(2003) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].

Entry informationi

Entry nameiA4D299_HUMAN
AccessioniPrimary (citable) accession number: A4D299
Entry historyi
Integrated into UniProtKB/TrEMBL: April 3, 2007
Last sequence update: April 3, 2007
Last modified: November 26, 2014
This is version 57 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into Uniref entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.