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Protein

Single-stranded DNA-binding protein

Gene

SSBP1

Organism
Homo sapiens (Human)
Status
Unreviewed-Annotation score: Annotation score: 2 out of 5-Experimental evidence at transcript leveli

Functioni

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Keywords - Ligandi

DNA-bindingUniRule annotationImported

Names & Taxonomyi

Protein namesi
Recommended name:
Single-stranded DNA-binding proteinUniRule annotation
Gene namesi
Name:SSBP1Imported
ORF Names:hCG_2014251Imported, tcag7.401Imported
OrganismiHomo sapiens (Human)Imported
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo

Subcellular locationi

  • Mitochondrion UniRule annotation

GO - Cellular componenti

Complete GO annotation...

Keywords - Cellular componenti

MitochondrionUniRule annotation

Pathology & Biotechi

Organism-specific databases

PharmGKBiPA36141.

Expressioni

Gene expression databases

ExpressionAtlasiA4D1U3. baseline and differential.

Interactioni

Protein-protein interaction databases

STRINGi9606.ENSP00000265304.

Structurei

3D structure databases

SMRiA4D1U3. Positions 26-140.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Phylogenomic databases

eggNOGiKOG1653. Eukaryota.
COG0629. LUCA.
HOVERGENiHBG001181.
KOiK03111.
OMAiRNPVTIF.
PhylomeDBiA4D1U3.

Family and domain databases

Gene3Di2.40.50.140. 1 hit.
HAMAPiMF_00984. SSB.
InterProiIPR012340. NA-bd_OB-fold.
IPR000424. Primosome_PriB/ssb.
IPR011344. ssDNA-bd.
[Graphical view]
PANTHERiPTHR10302. PTHR10302. 1 hit.
PfamiPF00436. SSB. 1 hit.
[Graphical view]
PIRSFiPIRSF002070. SSB. 1 hit.
SUPFAMiSSF50249. SSF50249. 1 hit.
TIGRFAMsiTIGR00621. ssb. 1 hit.
PROSITEiPS50935. SSB. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

A4D1U3-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MFRRPVLQVL RQFVRHESET TTSLVLERSL NRVHLLGRVG QDPVLRQVEG
60 70 80 90 100
KNPVTIFSLA TNEMWRSGDS EVYQLGDVSQ KTTWHRISVF RPGLRDVAYQ
110 120 130 140
YVKKGSRIYL EGKIDYGEYM DKNNVRRQAT TIIADNIIFL SDQTKEKE
Length:148
Mass (Da):17,260
Last modified:April 3, 2007 - v1
Checksum:i98EE9E396D5636C2
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
HQ206146 Genomic DNA. Translation: ADP92054.1.
HQ206147 Genomic DNA. Translation: ADP92055.1.
HQ206148 Genomic DNA. Translation: ADP92056.1.
HQ206149 Genomic DNA. Translation: ADP92057.1.
HQ206150 Genomic DNA. Translation: ADP92058.1.
HQ206151 Genomic DNA. Translation: ADP92059.1.
HQ206152 Genomic DNA. Translation: ADP92060.1.
HQ206153 Genomic DNA. Translation: ADP92061.1.
HQ206154 Genomic DNA. Translation: ADP92062.1.
HQ206155 Genomic DNA. Translation: ADP92063.1.
HQ206156 Genomic DNA. Translation: ADP92064.1.
HQ206157 Genomic DNA. Translation: ADP92065.1.
HQ206158 Genomic DNA. Translation: ADP92066.1.
HQ206159 Genomic DNA. Translation: ADP92067.1.
HQ206160 Genomic DNA. Translation: ADP92068.1.
HQ206161 Genomic DNA. Translation: ADP92069.1.
HQ206162 Genomic DNA. Translation: ADP92070.1.
HQ206163 Genomic DNA. Translation: ADP92071.1.
HQ206164 Genomic DNA. Translation: ADP92072.1.
HQ206165 Genomic DNA. Translation: ADP92073.1.
HQ206166 Genomic DNA. Translation: ADP92074.1.
HQ206167 Genomic DNA. Translation: ADP92075.1.
HQ206168 Genomic DNA. Translation: ADP92076.1.
HQ206169 Genomic DNA. Translation: ADP92077.1.
HQ206170 Genomic DNA. Translation: ADP92078.1.
HQ206171 Genomic DNA. Translation: ADP92079.1.
HQ206172 Genomic DNA. Translation: ADP92080.1.
HQ206173 Genomic DNA. Translation: ADP92081.1.
HQ206174 Genomic DNA. Translation: ADP92082.1.
HQ206175 Genomic DNA. Translation: ADP92083.1.
HQ206176 Genomic DNA. Translation: ADP92084.1.
HQ206177 Genomic DNA. Translation: ADP92085.1.
HQ206178 Genomic DNA. Translation: ADP92086.1.
HQ206179 Genomic DNA. Translation: ADP92087.1.
HQ206180 Genomic DNA. Translation: ADP92088.1.
HQ206181 Genomic DNA. Translation: ADP92089.1.
HQ206182 Genomic DNA. Translation: ADP92090.1.
HQ206183 Genomic DNA. Translation: ADP92091.1.
HQ206184 Genomic DNA. Translation: ADP92092.1.
HQ206185 Genomic DNA. Translation: ADP92093.1.
AK313033 mRNA. Translation: BAG35866.1.
CH236950 Genomic DNA. Translation: EAL24018.1.
CH471070 Genomic DNA. Translation: EAW83978.1.
CH471070 Genomic DNA. Translation: EAW83981.1.
RefSeqiNP_001243439.1. NM_001256510.1.
NP_001243440.1. NM_001256511.1.
NP_001243441.1. NM_001256512.1.
NP_001243442.1. NM_001256513.1.
NP_003134.1. NM_003143.2.
UniGeneiHs.490394.
Hs.740496.

Genome annotation databases

GeneIDi6742.
KEGGihsa:6742.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
HQ206146 Genomic DNA. Translation: ADP92054.1.
HQ206147 Genomic DNA. Translation: ADP92055.1.
HQ206148 Genomic DNA. Translation: ADP92056.1.
HQ206149 Genomic DNA. Translation: ADP92057.1.
HQ206150 Genomic DNA. Translation: ADP92058.1.
HQ206151 Genomic DNA. Translation: ADP92059.1.
HQ206152 Genomic DNA. Translation: ADP92060.1.
HQ206153 Genomic DNA. Translation: ADP92061.1.
HQ206154 Genomic DNA. Translation: ADP92062.1.
HQ206155 Genomic DNA. Translation: ADP92063.1.
HQ206156 Genomic DNA. Translation: ADP92064.1.
HQ206157 Genomic DNA. Translation: ADP92065.1.
HQ206158 Genomic DNA. Translation: ADP92066.1.
HQ206159 Genomic DNA. Translation: ADP92067.1.
HQ206160 Genomic DNA. Translation: ADP92068.1.
HQ206161 Genomic DNA. Translation: ADP92069.1.
HQ206162 Genomic DNA. Translation: ADP92070.1.
HQ206163 Genomic DNA. Translation: ADP92071.1.
HQ206164 Genomic DNA. Translation: ADP92072.1.
HQ206165 Genomic DNA. Translation: ADP92073.1.
HQ206166 Genomic DNA. Translation: ADP92074.1.
HQ206167 Genomic DNA. Translation: ADP92075.1.
HQ206168 Genomic DNA. Translation: ADP92076.1.
HQ206169 Genomic DNA. Translation: ADP92077.1.
HQ206170 Genomic DNA. Translation: ADP92078.1.
HQ206171 Genomic DNA. Translation: ADP92079.1.
HQ206172 Genomic DNA. Translation: ADP92080.1.
HQ206173 Genomic DNA. Translation: ADP92081.1.
HQ206174 Genomic DNA. Translation: ADP92082.1.
HQ206175 Genomic DNA. Translation: ADP92083.1.
HQ206176 Genomic DNA. Translation: ADP92084.1.
HQ206177 Genomic DNA. Translation: ADP92085.1.
HQ206178 Genomic DNA. Translation: ADP92086.1.
HQ206179 Genomic DNA. Translation: ADP92087.1.
HQ206180 Genomic DNA. Translation: ADP92088.1.
HQ206181 Genomic DNA. Translation: ADP92089.1.
HQ206182 Genomic DNA. Translation: ADP92090.1.
HQ206183 Genomic DNA. Translation: ADP92091.1.
HQ206184 Genomic DNA. Translation: ADP92092.1.
HQ206185 Genomic DNA. Translation: ADP92093.1.
AK313033 mRNA. Translation: BAG35866.1.
CH236950 Genomic DNA. Translation: EAL24018.1.
CH471070 Genomic DNA. Translation: EAW83978.1.
CH471070 Genomic DNA. Translation: EAW83981.1.
RefSeqiNP_001243439.1. NM_001256510.1.
NP_001243440.1. NM_001256511.1.
NP_001243441.1. NM_001256512.1.
NP_001243442.1. NM_001256513.1.
NP_003134.1. NM_003143.2.
UniGeneiHs.490394.
Hs.740496.

3D structure databases

SMRiA4D1U3. Positions 26-140.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi9606.ENSP00000265304.

Protocols and materials databases

DNASUi6742.
Structural Biology KnowledgebaseSearch...

Genome annotation databases

GeneIDi6742.
KEGGihsa:6742.

Organism-specific databases

CTDi6742.
PharmGKBiPA36141.

Phylogenomic databases

eggNOGiKOG1653. Eukaryota.
COG0629. LUCA.
HOVERGENiHBG001181.
KOiK03111.
OMAiRNPVTIF.
PhylomeDBiA4D1U3.

Miscellaneous databases

ChiTaRSiSSBP1. human.
GenomeRNAii6742.
NextBioi26300.

Gene expression databases

ExpressionAtlasiA4D1U3. baseline and differential.

Family and domain databases

Gene3Di2.40.50.140. 1 hit.
HAMAPiMF_00984. SSB.
InterProiIPR012340. NA-bd_OB-fold.
IPR000424. Primosome_PriB/ssb.
IPR011344. ssDNA-bd.
[Graphical view]
PANTHERiPTHR10302. PTHR10302. 1 hit.
PfamiPF00436. SSB. 1 hit.
[Graphical view]
PIRSFiPIRSF002070. SSB. 1 hit.
SUPFAMiSSF50249. SSF50249. 1 hit.
TIGRFAMsiTIGR00621. ssb. 1 hit.
PROSITEiPS50935. SSB. 1 hit.
[Graphical view]
ProtoNetiSearch...

Publicationsi

« Hide 'large scale' publications
  1. "The sequence of the human genome."
    Venter J.C., Adams M.D., Myers E.W., Li P.W., Mural R.J., Sutton G.G., Smith H.O., Yandell M., Evans C.A., Holt R.A., Gocayne J.D., Amanatides P., Ballew R.M., Huson D.H., Wortman J.R., Zhang Q., Kodira C.D., Zheng X.H.
    , Chen L., Skupski M., Subramanian G., Thomas P.D., Zhang J., Gabor Miklos G.L., Nelson C., Broder S., Clark A.G., Nadeau J., McKusick V.A., Zinder N., Levine A.J., Roberts R.J., Simon M., Slayman C., Hunkapiller M., Bolanos R., Delcher A., Dew I., Fasulo D., Flanigan M., Florea L., Halpern A., Hannenhalli S., Kravitz S., Levy S., Mobarry C., Reinert K., Remington K., Abu-Threideh J., Beasley E., Biddick K., Bonazzi V., Brandon R., Cargill M., Chandramouliswaran I., Charlab R., Chaturvedi K., Deng Z., Di Francesco V., Dunn P., Eilbeck K., Evangelista C., Gabrielian A.E., Gan W., Ge W., Gong F., Gu Z., Guan P., Heiman T.J., Higgins M.E., Ji R.R., Ke Z., Ketchum K.A., Lai Z., Lei Y., Li Z., Li J., Liang Y., Lin X., Lu F., Merkulov G.V., Milshina N., Moore H.M., Naik A.K., Narayan V.A., Neelam B., Nusskern D., Rusch D.B., Salzberg S., Shao W., Shue B., Sun J., Wang Z., Wang A., Wang X., Wang J., Wei M., Wides R., Xiao C., Yan C., Yao A., Ye J., Zhan M., Zhang W., Zhang H., Zhao Q., Zheng L., Zhong F., Zhong W., Zhu S., Zhao S., Gilbert D., Baumhueter S., Spier G., Carter C., Cravchik A., Woodage T., Ali F., An H., Awe A., Baldwin D., Baden H., Barnstead M., Barrow I., Beeson K., Busam D., Carver A., Center A., Cheng M.L., Curry L., Danaher S., Davenport L., Desilets R., Dietz S., Dodson K., Doup L., Ferriera S., Garg N., Gluecksmann A., Hart B., Haynes J., Haynes C., Heiner C., Hladun S., Hostin D., Houck J., Howland T., Ibegwam C., Johnson J., Kalush F., Kline L., Koduru S., Love A., Mann F., May D., McCawley S., McIntosh T., McMullen I., Moy M., Moy L., Murphy B., Nelson K., Pfannkoch C., Pratts E., Puri V., Qureshi H., Reardon M., Rodriguez R., Rogers Y.H., Romblad D., Ruhfel B., Scott R., Sitter C., Smallwood M., Stewart E., Strong R., Suh E., Thomas R., Tint N.N., Tse S., Vech C., Wang G., Wetter J., Williams S., Williams M., Windsor S., Winn-Deen E., Wolfe K., Zaveri J., Zaveri K., Abril J.F., Guigo R., Campbell M.J., Sjolander K.V., Karlak B., Kejariwal A., Mi H., Lazareva B., Hatton T., Narechania A., Diemer K., Muruganujan A., Guo N., Sato S., Bafna V., Istrail S., Lippert R., Schwartz R., Walenz B., Yooseph S., Allen D., Basu A., Baxendale J., Blick L., Caminha M., Carnes-Stine J., Caulk P., Chiang Y.H., Coyne M., Dahlke C., Mays A., Dombroski M., Donnelly M., Ely D., Esparham S., Fosler C., Gire H., Glanowski S., Glasser K., Glodek A., Gorokhov M., Graham K., Gropman B., Harris M., Heil J., Henderson S., Hoover J., Jennings D., Jordan C., Jordan J., Kasha J., Kagan L., Kraft C., Levitsky A., Lewis M., Liu X., Lopez J., Ma D., Majoros W., McDaniel J., Murphy S., Newman M., Nguyen T., Nguyen N., Nodell M., Pan S., Peck J., Peterson M., Rowe W., Sanders R., Scott J., Simpson M., Smith T., Sprague A., Stockwell T., Turner R., Venter E., Wang M., Wen M., Wu D., Wu M., Xia A., Zandieh A., Zhu X.
    Science 291:1304-1351(2001) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
  2. "Human chromosome 7: DNA sequence and biology."
    Scherer S.W., Cheung J., MacDonald J.R., Osborne L.R., Nakabayashi K., Herbrick J.A., Carson A.R., Parker-Katiraee L., Skaug J., Khaja R., Zhang J., Hudek A.K., Li M., Haddad M., Duggan G.E., Fernandez B.A., Kanematsu E., Gentles S.
    , Christopoulos C.C., Choufani S., Kwasnicka D., Zheng X.H., Lai Z., Nusskern D., Zhang Q., Gu Z., Lu F., Zeesman S., Nowaczyk M.J., Teshima I., Chitayat D., Shuman C., Weksberg R., Zackai E.H., Grebe T.A., Cox S.R., Kirkpatrick S.J., Rahman N., Friedman J.M., Heng H.H., Pelicci P.G., Lo-Coco F., Belloni E., Shaffer L.G., Pober B., Morton C.C., Gusella J.F., Bruns G.A., Korf B.R., Quade B.J., Ligon A.H., Ferguson H., Higgins A.W., Leach N.T., Herrick S.R., Lemyre E., Farra C.G., Kim H.G., Summers A.M., Gripp K.W., Roberts W., Szatmari P., Winsor E.J., Grzeschik K.H., Teebi A., Minassian B.A., Kere J., Armengol L., Pujana M.A., Estivill X., Wilson M.D., Koop B.F., Tosi S., Moore G.E., Boright A.P., Zlotorynski E., Kerem B., Kroisel P.M., Petek E., Oscier D.G., Mould S.J., Dohner H., Dohner K., Rommens J.M., Vincent J.B., Venter J.C., Li P.W., Mural R.J., Adams M.D., Tsui L.C.
    Science 300:767-772(2003) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
  3. Scherer S.W., Cheung J., MacDonald J.R., Osborne L.R., Nakabayashi K., Herbrick J.-A., Carson A.R., Parker-Katiraee L., Skaug J., Khaja R., Zhang J., Hudek A.K., Li M., Haddad M., Duggan G.E., Fernandez B.A., Kanematsu E., Gentles S.
    , Christopoulos C.C., Choufani S., Kwasnicka D., Zheng X.H., Nusskern D., Zhang Q., Gu Z., Lu F., Zeesman S., Teshima I., Chitayat D., Shuman C., Weksberg R., Zackai E.H., Grebe T.A., Cox S.R., Kirkpatrick S.J., Rahman N., Friedman J.M., Heng H.H.Q., Pelicci P., Lococo F., Belloni E., Shaffer L.G., Morton C.C., Pober B., Gusella J., Bruns G., Korf B.R., Quade B.J., Ligon A.H., Ferguson H., Higgins A.W., Leach N.T., Herrick S.R., Lemyre E., Farra C.G., Kim H.-G., Summers A.M., Gripp K.W., Roberts W., Szatmari P., Winsor E.J.T., Grzeschik K.-H., Teebi A., Minassian B.A., Kere J., Armengol L., Pujana M.Angel., Estivill X., Wilson M.D., Koop B.F., Tosi S., Moore G.E., Boright A.P., Zlotorynski E., Kerem B., Kroisel P.M., Petek E., Oscier D.G., Mould S.J., Doehner H., Doehner K., Rommens J.M., Vincent J.B., Venter J.C., Li P.W., Mural R.J., Adams M.D., Tsui L.-C.
    Submitted (JUN-2004) to the EMBL/GenBank/DDBJ databases
    Cited for: NUCLEOTIDE SEQUENCE.
  4. Cited for: NUCLEOTIDE SEQUENCE.
  5. "NEDO functional analysis of protein and research application project."
    Wakamatsu A., Yamamoto J., Kimura K., Kaida T., Tsuchiya K., Iida Y., Takayama Y., Murakawa K., Kanehori K., Andoh T., Kagawa N., Sato R., Kawamura Y., Tanaka S., Kisu Y., Sugano S., Goshima N., Nomura N., Isogai T.
    Submitted (JAN-2008) to the EMBL/GenBank/DDBJ databases
    Cited for: NUCLEOTIDE SEQUENCE.
    Tissue: AmygdalaImported.
  6. "Identification of rare DNA variants in mitochondrial disorders with improved array-based sequencing."
    Wang W., Shen P., Thiyagarajan S., Lin S., Palm C., Horvath R., Klopstock T., Cutler D., Pique L., Schrijver I., Davis R.W., Mindrinos M., Speed T.P., Scharfe C.
    Nucleic Acids Res. 39:44-58(2011) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE.

Entry informationi

Entry nameiA4D1U3_HUMAN
AccessioniPrimary (citable) accession number: A4D1U3
Entry historyi
Integrated into UniProtKB/TrEMBL: April 3, 2007
Last sequence update: April 3, 2007
Last modified: May 11, 2016
This is version 89 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.