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Protein

WD repeat-containing protein 91

Gene

WDR91

Organism
Homo sapiens (Human)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Experimental evidence at protein leveli

Functioni

Enzyme and pathway databases

SignaLinkiA4D1P6.

Names & Taxonomyi

Protein namesi
Recommended name:
WD repeat-containing protein 91
Gene namesi
Name:WDR91
ORF Names:HSPC049
OrganismiHomo sapiens (Human)
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
Proteomesi
  • UP000005640 Componenti: Chromosome 7

Organism-specific databases

HGNCiHGNC:24997. WDR91.

Pathology & Biotechi

Organism-specific databases

PharmGKBiPA162409166.

Polymorphism and mutation databases

BioMutaiWDR91.

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 747747WD repeat-containing protein 91PRO_0000295746Add
BLAST

Amino acid modifications

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Modified residuei256 – 2561PhosphoserineCombined sources
Modified residuei288 – 2881PhosphoserineCombined sources
Modified residuei293 – 2931PhosphoserineBy similarity

Keywords - PTMi

Phosphoprotein

Proteomic databases

EPDiA4D1P6.
MaxQBiA4D1P6.
PaxDbiA4D1P6.
PeptideAtlasiA4D1P6.
PRIDEiA4D1P6.

PTM databases

iPTMnetiA4D1P6.

Expressioni

Gene expression databases

BgeeiA4D1P6.
CleanExiHS_WDR91.
ExpressionAtlasiA4D1P6. baseline and differential.
GenevisibleiA4D1P6. HS.

Organism-specific databases

HPAiHPA024260.

Interactioni

Protein-protein interaction databases

BioGridi118837. 14 interactions.
IntActiA4D1P6. 6 interactions.
MINTiMINT-4716115.
STRINGi9606.ENSP00000346466.

Structurei

3D structure databases

ProteinModelPortaliA4D1P6.
SMRiA4D1P6. Positions 65-119, 424-660.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Repeati406 – 44540WD 1Add
BLAST
Repeati448 – 48841WD 2Add
BLAST
Repeati515 – 55541WD 3Add
BLAST
Repeati560 – 59940WD 4Add
BLAST
Repeati602 – 64140WD 5Add
BLAST
Repeati664 – 70239WD 6Add
BLAST
Repeati709 – 74739WD 7Add
BLAST

Coiled coil

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Coiled coili183 – 21533Sequence analysisAdd
BLAST

Sequence similaritiesi

Contains 7 WD repeats.PROSITE-ProRule annotation

Keywords - Domaini

Coiled coil, Repeat, WD repeat

Phylogenomic databases

eggNOGiKOG1333. Eukaryota.
ENOG410XQIX. LUCA.
GeneTreeiENSGT00390000001566.
HOVERGENiHBG057115.
InParanoidiA4D1P6.
OMAiINDDMPR.
PhylomeDBiA4D1P6.
TreeFamiTF317339.

Family and domain databases

Gene3Di2.130.10.10. 2 hits.
InterProiIPR015943. WD40/YVTN_repeat-like_dom.
IPR001680. WD40_repeat.
IPR017986. WD40_repeat_dom.
[Graphical view]
PfamiPF00400. WD40. 1 hit.
[Graphical view]
SMARTiSM00320. WD40. 5 hits.
[Graphical view]
SUPFAMiSSF50978. SSF50978. 1 hit.
PROSITEiPS50082. WD_REPEATS_2. 2 hits.
PS50294. WD_REPEATS_REGION. 2 hits.
[Graphical view]

Sequences (3)i

Sequence statusi: Complete.

This entry describes 3 isoformsi produced by alternative splicing. AlignAdd to basket

Isoform 1 (identifier: A4D1P6-1) [UniParc]FASTAAdd to basket

This isoform has been chosen as the 'canonical' sequence. All positional information in this entry refers to it. This is also the sequence that appears in the downloadable versions of the entry.

« Hide

        10         20         30         40         50
MAEAVERTDE LVREYLLFRG FTHTLRQLDA EIKADKEKGF RVDKIVDQLQ
60 70 80 90 100
QLMQVYDLAA LRDYWSYLER RLFSRLEDIY RPTIHKLKTS LFRFYLVYTI
110 120 130 140 150
QTNRNDKAQE FFAKQATELQ NQAEWKDWFV LPFLPSPDTN PTFATYFSRQ
160 170 180 190 200
WADTFIVSLH NFLSVLFQCM PVPVILNFDA ECQRTNQVQE ENEVLRQKLF
210 220 230 240 250
ALQAEIHRLK KEEQQPEEEE ALVQHKLPPY VSNMDRLGDS ELAMVCSQRN
260 270 280 290 300
ASLSQSPRVG FLSSLLPQSK KSPSRLSPAQ GPPQPQSSAK KESFGGQGTK
310 320 330 340 350
GKDPTSGAKD GKSLLSGLAT GESGWSQHRQ RRLQDHGKER KELFSTTTSQ
360 370 380 390 400
CAEKKPEASG PEAEPCPELH TEPVEPLTRA SSAGPEGGGV RPEQPFIVLG
410 420 430 440 450
QEEYGEHHSS IMHCRVDCSG RRVASLDVDG VIKVWSFNPI MQTKASSISK
460 470 480 490 500
SPLLSLEWAT KRDRLLLLGS GVGTVRLYDT EAKKNLCEIN INDNMPRILS
510 520 530 540 550
LACSPNGASF VCSAAAPSLT SQVDFSAPDI GSKGMNQVPG RLLLWDTKTM
560 570 580 590 600
KQQLQFSLDP EPIAINCTAF NHNGNLLVTG AADGVIRLFD MQQHECAMSW
610 620 630 640 650
RAHYGEVYSV EFSYDENTVY SIGEDGKFIQ WNIHKSGLKV SEYSLPSDAT
660 670 680 690 700
GPFVLSGYSG YKQVQVPRGR LFAFDSEGNY MLTCSATGGV IYKLGGDEKV
710 720 730 740
LESCLSLGGH RAPVVTVDWS TAMDCGTCLT ASMDGKIKLT TLLAHKA
Length:747
Mass (Da):83,344
Last modified:November 30, 2010 - v2
Checksum:iA93CF7F02D12629A
GO
Isoform 2 (identifier: A4D1P6-2) [UniParc]FASTAAdd to basket

The sequence of this isoform differs from the canonical sequence as follows:
     590-636: DMQQHECAMS...KFIQWNIHKS → VHPVEHPQEW...SSPQGPTLRF
     637-747: Missing.

Note: No experimental confirmation available.
Show »
Length:636
Mass (Da):71,352
Checksum:iBF7826528F2047B5
GO
Isoform 3 (identifier: A4D1P6-3) [UniParc]FASTAAdd to basket

The sequence of this isoform differs from the canonical sequence as follows:
     351-365: CAEKKPEASGPEAEP → VWGCPEHPWGHSCSY
     366-747: Missing.

Note: No experimental confirmation available.
Show »
Length:365
Mass (Da):42,112
Checksum:i8E984767FD792012
GO

Sequence cautioni

The sequence AAF29021.1 differs from that shown. Reason: Frameshift at positions 136, 161, 166, 381, 392, 400, 405, 424, 442, 448, 458, 462, 501, 505, 508, 605, 626, 646, 712 and 736. Curated

Experimental Info

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Sequence conflicti302 – 3021K → R in BAA91785 (PubMed:14702039).Curated
Sequence conflicti449 – 4491S → F in AAF29021 (PubMed:11042152).Curated
Sequence conflicti510 – 5101F → L in AAF29021 (PubMed:11042152).Curated
Sequence conflicti706 – 7061S → K in AAF29021 (PubMed:11042152).Curated

Natural variant

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Natural varianti257 – 2571P → L.6 Publications
Corresponds to variant rs292592 [ dbSNP | Ensembl ].
VAR_033358

Alternative sequence

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Alternative sequencei351 – 36515CAEKK…PEAEP → VWGCPEHPWGHSCSY in isoform 3. 1 PublicationVSP_027058Add
BLAST
Alternative sequencei366 – 747382Missing in isoform 3. 1 PublicationVSP_027059Add
BLAST
Alternative sequencei590 – 63647DMQQH…NIHKS → VHPVEHPQEWPQGIRVQPPL RCHGPLCAVWIQRLQAGSSP QGPTLRF in isoform 2. 1 PublicationVSP_027060Add
BLAST
Alternative sequencei637 – 747111Missing in isoform 2. 1 PublicationVSP_027061Add
BLAST

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AF161534 mRNA. Translation: AAF29021.1. Frameshift.
AK001606 mRNA. Translation: BAA91785.1.
AK022935 mRNA. Translation: BAB14316.1.
BX640957 mRNA. Translation: CAE45977.1.
AC009542 Genomic DNA. No translation available.
AC083862 Genomic DNA. No translation available.
CH236950 Genomic DNA. Translation: EAL24062.1.
BC009939 mRNA. Translation: AAH09939.2.
BC017246 mRNA. Translation: AAH17246.1.
BC063394 mRNA. Translation: AAH63394.1.
AL136940 mRNA. Translation: CAB66874.2.
CR533561 mRNA. Translation: CAG38592.1.
CCDSiCCDS34758.1. [A4D1P6-1]
RefSeqiNP_054868.3. NM_014149.3. [A4D1P6-1]
UniGeneiHs.459858.

Genome annotation databases

EnsembliENST00000354475; ENSP00000346466; ENSG00000105875. [A4D1P6-1]
GeneIDi29062.
KEGGihsa:29062.
UCSCiuc003vsp.3. human. [A4D1P6-1]

Keywords - Coding sequence diversityi

Alternative splicing, Polymorphism

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AF161534 mRNA. Translation: AAF29021.1. Frameshift.
AK001606 mRNA. Translation: BAA91785.1.
AK022935 mRNA. Translation: BAB14316.1.
BX640957 mRNA. Translation: CAE45977.1.
AC009542 Genomic DNA. No translation available.
AC083862 Genomic DNA. No translation available.
CH236950 Genomic DNA. Translation: EAL24062.1.
BC009939 mRNA. Translation: AAH09939.2.
BC017246 mRNA. Translation: AAH17246.1.
BC063394 mRNA. Translation: AAH63394.1.
AL136940 mRNA. Translation: CAB66874.2.
CR533561 mRNA. Translation: CAG38592.1.
CCDSiCCDS34758.1. [A4D1P6-1]
RefSeqiNP_054868.3. NM_014149.3. [A4D1P6-1]
UniGeneiHs.459858.

3D structure databases

ProteinModelPortaliA4D1P6.
SMRiA4D1P6. Positions 65-119, 424-660.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

BioGridi118837. 14 interactions.
IntActiA4D1P6. 6 interactions.
MINTiMINT-4716115.
STRINGi9606.ENSP00000346466.

PTM databases

iPTMnetiA4D1P6.

Polymorphism and mutation databases

BioMutaiWDR91.

Proteomic databases

EPDiA4D1P6.
MaxQBiA4D1P6.
PaxDbiA4D1P6.
PeptideAtlasiA4D1P6.
PRIDEiA4D1P6.

Protocols and materials databases

DNASUi29062.
Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENST00000354475; ENSP00000346466; ENSG00000105875. [A4D1P6-1]
GeneIDi29062.
KEGGihsa:29062.
UCSCiuc003vsp.3. human. [A4D1P6-1]

Organism-specific databases

CTDi29062.
GeneCardsiWDR91.
H-InvDBHIX0167835.
HGNCiHGNC:24997. WDR91.
HPAiHPA024260.
neXtProtiNX_A4D1P6.
PharmGKBiPA162409166.
GenAtlasiSearch...

Phylogenomic databases

eggNOGiKOG1333. Eukaryota.
ENOG410XQIX. LUCA.
GeneTreeiENSGT00390000001566.
HOVERGENiHBG057115.
InParanoidiA4D1P6.
OMAiINDDMPR.
PhylomeDBiA4D1P6.
TreeFamiTF317339.

Enzyme and pathway databases

SignaLinkiA4D1P6.

Miscellaneous databases

ChiTaRSiWDR91. human.
GenomeRNAii29062.
PROiA4D1P6.

Gene expression databases

BgeeiA4D1P6.
CleanExiHS_WDR91.
ExpressionAtlasiA4D1P6. baseline and differential.
GenevisibleiA4D1P6. HS.

Family and domain databases

Gene3Di2.130.10.10. 2 hits.
InterProiIPR015943. WD40/YVTN_repeat-like_dom.
IPR001680. WD40_repeat.
IPR017986. WD40_repeat_dom.
[Graphical view]
PfamiPF00400. WD40. 1 hit.
[Graphical view]
SMARTiSM00320. WD40. 5 hits.
[Graphical view]
SUPFAMiSSF50978. SSF50978. 1 hit.
PROSITEiPS50082. WD_REPEATS_2. 2 hits.
PS50294. WD_REPEATS_REGION. 2 hits.
[Graphical view]
ProtoNetiSearch...

Publicationsi

  1. "Cloning and functional analysis of cDNAs with open reading frames for 300 previously undefined genes expressed in CD34+ hematopoietic stem/progenitor cells."
    Zhang Q.-H., Ye M., Wu X.-Y., Ren S.-X., Zhao M., Zhao C.-J., Fu G., Shen Y., Fan H.-Y., Lu G., Zhong M., Xu X.-R., Han Z.-G., Zhang J.-W., Tao J., Huang Q.-H., Zhou J., Hu G.-X.
    , Gu J., Chen S.-J., Chen Z.
    Genome Res. 10:1546-1560(2000) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 1), VARIANT LEU-257.
    Tissue: Blood.
  2. "Complete sequencing and characterization of 21,243 full-length human cDNAs."
    Ota T., Suzuki Y., Nishikawa T., Otsuki T., Sugiyama T., Irie R., Wakamatsu A., Hayashi K., Sato H., Nagai K., Kimura K., Makita H., Sekine M., Obayashi M., Nishi T., Shibahara T., Tanaka T., Ishii S.
    , Yamamoto J., Saito K., Kawai Y., Isono Y., Nakamura Y., Nagahari K., Murakami K., Yasuda T., Iwayanagi T., Wagatsuma M., Shiratori A., Sudo H., Hosoiri T., Kaku Y., Kodaira H., Kondo H., Sugawara M., Takahashi M., Kanda K., Yokoi T., Furuya T., Kikkawa E., Omura Y., Abe K., Kamihara K., Katsuta N., Sato K., Tanikawa M., Yamazaki M., Ninomiya K., Ishibashi T., Yamashita H., Murakawa K., Fujimori K., Tanai H., Kimata M., Watanabe M., Hiraoka S., Chiba Y., Ishida S., Ono Y., Takiguchi S., Watanabe S., Yosida M., Hotuta T., Kusano J., Kanehori K., Takahashi-Fujii A., Hara H., Tanase T.-O., Nomura Y., Togiya S., Komai F., Hara R., Takeuchi K., Arita M., Imose N., Musashino K., Yuuki H., Oshima A., Sasaki N., Aotsuka S., Yoshikawa Y., Matsunawa H., Ichihara T., Shiohata N., Sano S., Moriya S., Momiyama H., Satoh N., Takami S., Terashima Y., Suzuki O., Nakagawa S., Senoh A., Mizoguchi H., Goto Y., Shimizu F., Wakebe H., Hishigaki H., Watanabe T., Sugiyama A., Takemoto M., Kawakami B., Yamazaki M., Watanabe K., Kumagai A., Itakura S., Fukuzumi Y., Fujimori Y., Komiyama M., Tashiro H., Tanigami A., Fujiwara T., Ono T., Yamada K., Fujii Y., Ozaki K., Hirao M., Ohmori Y., Kawabata A., Hikiji T., Kobatake N., Inagaki H., Ikema Y., Okamoto S., Okitani R., Kawakami T., Noguchi S., Itoh T., Shigeta K., Senba T., Matsumura K., Nakajima Y., Mizuno T., Morinaga M., Sasaki M., Togashi T., Oyama M., Hata H., Watanabe M., Komatsu T., Mizushima-Sugano J., Satoh T., Shirai Y., Takahashi Y., Nakagawa K., Okumura K., Nagase T., Nomura N., Kikuchi H., Masuho Y., Yamashita R., Nakai K., Yada T., Nakamura Y., Ohara O., Isogai T., Sugano S.
    Nat. Genet. 36:40-45(2004) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORMS 1 AND 2).
    Tissue: Teratocarcinoma.
  3. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 3), VARIANT LEU-257.
    Tissue: Uterus.
  4. "The DNA sequence of human chromosome 7."
    Hillier L.W., Fulton R.S., Fulton L.A., Graves T.A., Pepin K.H., Wagner-McPherson C., Layman D., Maas J., Jaeger S., Walker R., Wylie K., Sekhon M., Becker M.C., O'Laughlin M.D., Schaller M.E., Fewell G.A., Delehaunty K.D., Miner T.L.
    , Nash W.E., Cordes M., Du H., Sun H., Edwards J., Bradshaw-Cordum H., Ali J., Andrews S., Isak A., Vanbrunt A., Nguyen C., Du F., Lamar B., Courtney L., Kalicki J., Ozersky P., Bielicki L., Scott K., Holmes A., Harkins R., Harris A., Strong C.M., Hou S., Tomlinson C., Dauphin-Kohlberg S., Kozlowicz-Reilly A., Leonard S., Rohlfing T., Rock S.M., Tin-Wollam A.-M., Abbott A., Minx P., Maupin R., Strowmatt C., Latreille P., Miller N., Johnson D., Murray J., Woessner J.P., Wendl M.C., Yang S.-P., Schultz B.R., Wallis J.W., Spieth J., Bieri T.A., Nelson J.O., Berkowicz N., Wohldmann P.E., Cook L.L., Hickenbotham M.T., Eldred J., Williams D., Bedell J.A., Mardis E.R., Clifton S.W., Chissoe S.L., Marra M.A., Raymond C., Haugen E., Gillett W., Zhou Y., James R., Phelps K., Iadanoto S., Bubb K., Simms E., Levy R., Clendenning J., Kaul R., Kent W.J., Furey T.S., Baertsch R.A., Brent M.R., Keibler E., Flicek P., Bork P., Suyama M., Bailey J.A., Portnoy M.E., Torrents D., Chinwalla A.T., Gish W.R., Eddy S.R., McPherson J.D., Olson M.V., Eichler E.E., Green E.D., Waterston R.H., Wilson R.K.
    Nature 424:157-164(2003) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
  5. "Human chromosome 7: DNA sequence and biology."
    Scherer S.W., Cheung J., MacDonald J.R., Osborne L.R., Nakabayashi K., Herbrick J.-A., Carson A.R., Parker-Katiraee L., Skaug J., Khaja R., Zhang J., Hudek A.K., Li M., Haddad M., Duggan G.E., Fernandez B.A., Kanematsu E., Gentles S.
    , Christopoulos C.C., Choufani S., Kwasnicka D., Zheng X.H., Lai Z., Nusskern D.R., Zhang Q., Gu Z., Lu F., Zeesman S., Nowaczyk M.J., Teshima I., Chitayat D., Shuman C., Weksberg R., Zackai E.H., Grebe T.A., Cox S.R., Kirkpatrick S.J., Rahman N., Friedman J.M., Heng H.H.Q., Pelicci P.G., Lo-Coco F., Belloni E., Shaffer L.G., Pober B., Morton C.C., Gusella J.F., Bruns G.A.P., Korf B.R., Quade B.J., Ligon A.H., Ferguson H., Higgins A.W., Leach N.T., Herrick S.R., Lemyre E., Farra C.G., Kim H.-G., Summers A.M., Gripp K.W., Roberts W., Szatmari P., Winsor E.J.T., Grzeschik K.-H., Teebi A., Minassian B.A., Kere J., Armengol L., Pujana M.A., Estivill X., Wilson M.D., Koop B.F., Tosi S., Moore G.E., Boright A.P., Zlotorynski E., Kerem B., Kroisel P.M., Petek E., Oscier D.G., Mould S.J., Doehner H., Doehner K., Rommens J.M., Vincent J.B., Venter J.C., Li P.W., Mural R.J., Adams M.D., Tsui L.-C.
    Science 300:767-772(2003) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA], VARIANT LEU-257.
  6. "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
    The MGC Project Team
    Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 1), VARIANT LEU-257.
    Tissue: Brain, Colon and Uterus.
  7. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] OF 30-747 (ISOFORM 1), VARIANT LEU-257.
    Tissue: Uterus.
  8. "Cloning of human full open reading frames in Gateway(TM) system entry vector (pDONR201)."
    Ebert L., Schick M., Neubert P., Schatten R., Henze S., Korn B.
    Submitted (JUN-2004) to the EMBL/GenBank/DDBJ databases
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] OF 53-747 (ISOFORM 1), VARIANT LEU-257.
  9. "A probability-based approach for high-throughput protein phosphorylation analysis and site localization."
    Beausoleil S.A., Villen J., Gerber S.A., Rush J., Gygi S.P.
    Nat. Biotechnol. 24:1285-1292(2006) [PubMed] [Europe PMC] [Abstract]
    Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-256, IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].
    Tissue: Cervix carcinoma.
  10. Cited for: IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].
  11. "Toward a comprehensive characterization of a human cancer cell phosphoproteome."
    Zhou H., Di Palma S., Preisinger C., Peng M., Polat A.N., Heck A.J., Mohammed S.
    J. Proteome Res. 12:260-271(2013) [PubMed] [Europe PMC] [Abstract]
    Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-288, IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].
    Tissue: Erythroleukemia.

Entry informationi

Entry nameiWDR91_HUMAN
AccessioniPrimary (citable) accession number: A4D1P6
Secondary accession number(s): A6NK54
, C9JMI4, Q6FI65, Q6MZQ1, Q6P4I1, Q96AE5, Q96G63, Q9H062, Q9H9B6, Q9NVG7, Q9NZY6
Entry historyi
Integrated into UniProtKB/Swiss-Prot: July 24, 2007
Last sequence update: November 30, 2010
Last modified: July 6, 2016
This is version 86 of the entry and version 2 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Human chromosome 7
    Human chromosome 7: entries, gene names and cross-references to MIM
  2. Human entries with polymorphisms or disease mutations
    List of human entries with polymorphisms or disease mutations
  3. Human polymorphisms and disease mutations
    Index of human polymorphisms and disease mutations
  4. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.