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Protein
Submitted name:

Ubiquitin-conjugating enzyme E2H (UBC8 homolog, yeast)

Gene

UBE2H

Organism
Homo sapiens (Human)
Status
Unreviewed-Annotation score: Annotation score: 1 out of 5-Experimental evidence at transcript leveli

Functioni

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Active sitei87Glycyl thioester intermediatePROSITE-ProRule annotation1

GO - Molecular functioni

GO - Biological processi

Keywordsi

Biological processUbl conjugation pathwayUniRule annotationSAAS annotation
LigandATP-bindingUniRule annotation, Nucleotide-binding

Names & Taxonomyi

Protein namesi
Submitted name:
Ubiquitin-conjugating enzyme E2H (UBC8 homolog, yeast)Imported
Submitted name:
Ubiquitin-conjugating enzyme E2H (UBC8 homolog, yeast), isoform CRA_bImported
Submitted name:
Ubiquitin-conjugating enzyme E2H isoform 1Imported
Submitted name:
Ubiquitin-conjugating enzyme E2H isoform AImported
Gene namesi
Name:UBE2HImported
ORF Names:hCG_18056Imported, tcag7.352Imported
OrganismiHomo sapiens (Human)Imported
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo

Organism-specific databases

EuPathDBiHostDB:ENSG00000186591.11.

Pathology & Biotechi

Organism-specific databases

PharmGKBiPA37133.

Expressioni

Gene expression databases

BgeeiENSG00000186591.

Interactioni

Protein-protein interaction databases

IntActiA4D1L5. 1 interactor.

Structurei

3D structure databases

SMRiA4D1L5.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini31 – 139UBIQUITIN_CONJUGAT_2InterPro annotationAdd BLAST109

Sequence similaritiesi

Belongs to the ubiquitin-conjugating enzyme family.PROSITE-ProRule annotationSAAS annotation

Phylogenomic databases

eggNOGiKOG0416. Eukaryota.
ENOG410XRC5. LUCA.
HOVERGENiHBG063308.
KOiK10576.
OMAiMRHPKEY.
OrthoDBiEOG091G0RI1.

Family and domain databases

CDDicd00195. UBCc. 1 hit.
Gene3Di3.10.110.10. 1 hit.
InterProiView protein in InterPro
IPR000608. UBQ-conjugat_E2.
IPR023313. UBQ-conjugating_AS.
IPR016135. UBQ-conjugating_enzyme/RWD.
PfamiView protein in Pfam
PF00179. UQ_con. 1 hit.
SUPFAMiSSF54495. SSF54495. 1 hit.
PROSITEiView protein in PROSITE
PS00183. UBIQUITIN_CONJUGAT_1. 1 hit.
PS50127. UBIQUITIN_CONJUGAT_2. 1 hit.

Sequencei

Sequence statusi: Complete.

A4D1L5-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MSSPSPGKRR MDTDVVKLIE SKHEVTILGG LNEFVVKFYG PQGTPYEGGV
60 70 80 90 100
WKVRVDLPDK YPFKSPSIGF MNKIFHPNID EASGTVCLDV INQTWTALYD
110 120 130 140 150
LTNIFESFLP QLLAYPNPID PLNGDAAAMY LHRPEEYKQK IKEYIQKYAT
160 170 180
EEALKEQEEG TGDSSSESSM SDFSEDEAQD MEL
Length:183
Mass (Da):20,655
Last modified:April 3, 2007 - v1
Checksum:i3DD5D365945F708C
GO

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Non-terminal residuei183Imported1

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
KJ534959 mRNA. Translation: AHW56599.1.
AB451490 mRNA. Translation: BAG70304.1.
CH236950 Genomic DNA. Translation: EAL24098.1.
CH471070 Genomic DNA. Translation: EAW83734.1.
CH471070 Genomic DNA. Translation: EAW83735.1.
CH471070 Genomic DNA. Translation: EAW83737.1.
RefSeqiNP_003335.1. NM_003344.3.
UniGeneiHs.643548.

Genome annotation databases

GeneIDi7328.
KEGGihsa:7328.

Similar proteinsi

Entry informationi

Entry nameiA4D1L5_HUMAN
AccessioniPrimary (citable) accession number: A4D1L5
Entry historyiIntegrated into UniProtKB/TrEMBL: April 3, 2007
Last sequence update: April 3, 2007
Last modified: November 22, 2017
This is version 99 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.