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Protein
Submitted name:

Ubiquitin-conjugating enzyme E2H (UBC8 homolog, yeast)

Gene

UBE2H

Organism
Homo sapiens (Human)
Status
Unreviewed-Annotation score: Annotation score: 1 out of 5-Experimental evidence at transcript leveli

Functioni

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Keywords - Biological processi

Ubl conjugation pathwayUniRule annotationSAAS annotation

Keywords - Ligandi

ATP-bindingUniRule annotation, Nucleotide-binding

Names & Taxonomyi

Protein namesi
Submitted name:
Ubiquitin-conjugating enzyme E2H (UBC8 homolog, yeast)Imported
Submitted name:
Ubiquitin-conjugating enzyme E2H (UBC8 homolog, yeast), isoform CRA_bImported
Submitted name:
Ubiquitin-conjugating enzyme E2H isoform 1Imported
Submitted name:
Ubiquitin-conjugating enzyme E2H isoform AImported
Gene namesi
Name:UBE2HImported
ORF Names:hCG_18056Imported, tcag7.352Imported
OrganismiHomo sapiens (Human)Imported
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo

Pathology & Biotechi

Organism-specific databases

PharmGKBiPA37133.

Expressioni

Gene expression databases

BgeeiENSG00000186591.

Interactioni

Protein-protein interaction databases

STRINGi9606.ENSP00000347836.

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini31 – 139UBIQUITIN_CONJUGAT_2InterPro annotationAdd BLAST109

Sequence similaritiesi

Belongs to the ubiquitin-conjugating enzyme family.UniRule annotationSAAS annotation

Phylogenomic databases

eggNOGiKOG0416. Eukaryota.
ENOG410XRC5. LUCA.
HOVERGENiHBG063308.
KOiK10576.
OMAiVWKVRVH.
OrthoDBiEOG091G0RI1.

Family and domain databases

Gene3Di3.10.110.10. 1 hit.
InterProiIPR000608. UBQ-conjugat_E2.
IPR023313. UBQ-conjugating_AS.
IPR016135. UBQ-conjugating_enzyme/RWD.
[Graphical view]
PfamiPF00179. UQ_con. 1 hit.
[Graphical view]
SUPFAMiSSF54495. SSF54495. 1 hit.
PROSITEiPS00183. UBIQUITIN_CONJUGAT_1. 1 hit.
PS50127. UBIQUITIN_CONJUGAT_2. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

A4D1L5-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MSSPSPGKRR MDTDVVKLIE SKHEVTILGG LNEFVVKFYG PQGTPYEGGV
60 70 80 90 100
WKVRVDLPDK YPFKSPSIGF MNKIFHPNID EASGTVCLDV INQTWTALYD
110 120 130 140 150
LTNIFESFLP QLLAYPNPID PLNGDAAAMY LHRPEEYKQK IKEYIQKYAT
160 170 180
EEALKEQEEG TGDSSSESSM SDFSEDEAQD MEL
Length:183
Mass (Da):20,655
Last modified:April 3, 2007 - v1
Checksum:i3DD5D365945F708C
GO

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Non-terminal residuei183Imported1

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
KJ534959 mRNA. Translation: AHW56599.1.
AB451490 mRNA. Translation: BAG70304.1.
CH236950 Genomic DNA. Translation: EAL24098.1.
CH471070 Genomic DNA. Translation: EAW83734.1.
CH471070 Genomic DNA. Translation: EAW83735.1.
CH471070 Genomic DNA. Translation: EAW83737.1.
RefSeqiNP_003335.1. NM_003344.3.
UniGeneiHs.643548.

Genome annotation databases

GeneIDi7328.
KEGGihsa:7328.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
KJ534959 mRNA. Translation: AHW56599.1.
AB451490 mRNA. Translation: BAG70304.1.
CH236950 Genomic DNA. Translation: EAL24098.1.
CH471070 Genomic DNA. Translation: EAW83734.1.
CH471070 Genomic DNA. Translation: EAW83735.1.
CH471070 Genomic DNA. Translation: EAW83737.1.
RefSeqiNP_003335.1. NM_003344.3.
UniGeneiHs.643548.

3D structure databases

ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi9606.ENSP00000347836.

Protocols and materials databases

DNASUi7328.
Structural Biology KnowledgebaseSearch...

Genome annotation databases

GeneIDi7328.
KEGGihsa:7328.

Organism-specific databases

CTDi7328.
PharmGKBiPA37133.

Phylogenomic databases

eggNOGiKOG0416. Eukaryota.
ENOG410XRC5. LUCA.
HOVERGENiHBG063308.
KOiK10576.
OMAiVWKVRVH.
OrthoDBiEOG091G0RI1.

Miscellaneous databases

ChiTaRSiUBE2H. human.
GenomeRNAii7328.

Gene expression databases

BgeeiENSG00000186591.

Family and domain databases

Gene3Di3.10.110.10. 1 hit.
InterProiIPR000608. UBQ-conjugat_E2.
IPR023313. UBQ-conjugating_AS.
IPR016135. UBQ-conjugating_enzyme/RWD.
[Graphical view]
PfamiPF00179. UQ_con. 1 hit.
[Graphical view]
SUPFAMiSSF54495. SSF54495. 1 hit.
PROSITEiPS00183. UBIQUITIN_CONJUGAT_1. 1 hit.
PS50127. UBIQUITIN_CONJUGAT_2. 1 hit.
[Graphical view]
ProtoNetiSearch...

Entry informationi

Entry nameiA4D1L5_HUMAN
AccessioniPrimary (citable) accession number: A4D1L5
Entry historyi
Integrated into UniProtKB/TrEMBL: April 3, 2007
Last sequence update: April 3, 2007
Last modified: November 30, 2016
This is version 90 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.