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Protein
Submitted name:

Fibrinogen-like 2

Gene

FGL2

Organism
Homo sapiens (Human)
Status
Unreviewed-Annotation score: -Experimental evidence at transcript leveli

Functioni

GO - Molecular functioni

Names & Taxonomyi

Protein namesi
Submitted name:
Fibrinogen-like 2Imported
Submitted name:
cDNA, FLJ93065, Homo sapiens fibrinogen-like 2 (FGL2), mRNAImported
Gene namesi
Name:FGL2Imported
ORF Names:hCG_39113Imported, tcag7.1277Imported
OrganismiHomo sapiens (Human)Imported
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo

Organism-specific databases

EuPathDBiHostDB:ENSG00000127951.5

Pathology & Biotechi

Organism-specific databases

PharmGKBiPA28134

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Signal peptidei1 – 23Sequence analysisAdd BLAST23
ChainiPRO_501429687024 – 439Sequence analysisAdd BLAST416

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Disulfide bondi213 ↔ 242PROSITE-ProRule annotation
Disulfide bondi371 ↔ 384PROSITE-ProRule annotation

Keywords - PTMi

Disulfide bondPROSITE-ProRule annotationSAAS annotation

Proteomic databases

PRIDEiA4D1B8

Expressioni

Gene expression databases

BgeeiENSG00000127951
ExpressionAtlasiA4D1B8 baseline and differential

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini204 – 436Fibrinogen C-terminalInterPro annotationAdd BLAST233

Coiled coil

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Coiled coili75 – 102Sequence analysisAdd BLAST28
Coiled coili130 – 164Sequence analysisAdd BLAST35

Keywords - Domaini

Coiled coilSequence analysis, SignalSequence analysis

Phylogenomic databases

eggNOGiKOG2579 Eukaryota
ENOG410ZYS4 LUCA
HOVERGENiHBG105002
OMAiFYVANEF
OrthoDBiEOG091G03M1

Family and domain databases

CDDicd00087 FReD, 1 hit
InterProiView protein in InterPro
IPR033083 Fgl2
IPR036056 Fibrinogen-like_C
IPR002181 Fibrinogen_a/b/g_C_dom
IPR020837 Fibrinogen_CS
PANTHERiPTHR19143:SF189 PTHR19143:SF189, 1 hit
PfamiView protein in Pfam
PF00147 Fibrinogen_C, 1 hit
SMARTiView protein in SMART
SM00186 FBG, 1 hit
SUPFAMiSSF56496 SSF56496, 1 hit
PROSITEiView protein in PROSITE
PS00514 FIBRINOGEN_C_1, 1 hit
PS51406 FIBRINOGEN_C_2, 1 hit

Sequencei

Sequence statusi: Complete.

A4D1B8-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MKLANWYWLS SAVLATYGFL VVANNETEEI KDERAKDVCP VRLESRGKCE
60 70 80 90 100
EAGECPYQVS LPPLTIQLPK QFSRIEEVFK EVQNLKEIVN SLKKSCQDCK
110 120 130 140 150
LQADDNGDPG RNGLLLPSTG APGEVGDNRV RELESEVNKL SSELKNAKEE
160 170 180 190 200
INVLHGRLEK LNLVNMNNIE NYVDSKVANL TFVVNSLDGK CSKCPSQEQI
210 220 230 240 250
QSRPVQHLIY KDCSDYYAIG KRSSETYRVT PDPKNSSFEV YCDMETMGGG
260 270 280 290 300
WTVLQARLDG STNFTRTWQD YKAGFGNLRR EFWLGNDKIH LLTKSKEMIL
310 320 330 340 350
RIDLEDFNGV ELYALYDQFY VANEFLKYRL HVGNYNGTAG DALRFNKHYN
360 370 380 390 400
HDLKFFTTPD KDNDRYPSGN CGLYYSSGWW FDACLSANLN GKYYHQKYRG
410 420 430
VRNGIFWGTW PGVSEAHPGG YKSSFKEAKM MIRPKHFKP
Length:439
Mass (Da):50,229
Last modified:April 3, 2007 - v1
Checksum:iDF34656288E49E68
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AK312672 mRNA Translation: BAG35554.1
CH236949 Genomic DNA Translation: EAL24202.1
CH471091 Genomic DNA Translation: EAW77045.1
RefSeqiNP_006673.1, NM_006682.2
UniGeneiHs.520989

Genome annotation databases

GeneIDi10875
KEGGihsa:10875

Similar proteinsi

Entry informationi

Entry nameiA4D1B8_HUMAN
AccessioniPrimary (citable) accession number: A4D1B8
Entry historyiIntegrated into UniProtKB/TrEMBL: April 3, 2007
Last sequence update: April 3, 2007
Last modified: May 23, 2018
This is version 100 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

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