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Protein
Submitted name:

Neuropeptide Y

Gene

NPY

Organism
Homo sapiens (Human)
Status
Unreviewed-Annotation score: Annotation score: 2 out of 5-Experimental evidence at transcript leveli

Functioni

GO - Biological processi

Complete GO annotation...

Keywords - Molecular functioni

NeuropeptideImported

Names & Taxonomyi

Protein namesi
Submitted name:
Neuropeptide YImported
Submitted name:
cDNA, FLJ92442, Homo sapiens neuropeptide Y (NPY), mRNAImported
Gene namesi
Name:NPYImported
ORF Names:hCG_37313Imported, tcag7.159Imported
OrganismiHomo sapiens (Human)
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo

Subcellular locationi

  • Secreted SAAS annotation

GO - Cellular componenti

Complete GO annotation...

Keywords - Cellular componenti

SecretedSAAS annotation

Pathology & Biotechi

Organism-specific databases

PharmGKBiPA255.

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Signal peptidei1 – 2828Sequence analysisAdd
BLAST
Chaini29 – 9769Sequence analysisPRO_5007634698Add
BLAST

Expressioni

Gene expression databases

BgeeiENSG00000122585.

Interactioni

Protein-protein interaction databases

STRINGi9606.ENSP00000242152.

Structurei

3D structure databases

SMRiA4D158. Positions 29-64.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the NPY family.UniRule annotationSAAS annotation

Keywords - Domaini

SignalSequence analysis

Phylogenomic databases

eggNOGiENOG410J0KC. Eukaryota.
ENOG41128I2. LUCA.
HOVERGENiHBG006485.
KOiK05232.
OMAiFEDPSMW.
OrthoDBiEOG091G0ZRE.
PhylomeDBiA4D158.

Family and domain databases

CDDicd00126. PAH. 1 hit.
InterProiIPR001955. Pancreatic_hormone-like.
IPR020392. Pancreatic_hormone-like_CS.
[Graphical view]
PANTHERiPTHR10533. PTHR10533. 1 hit.
PfamiPF00159. Hormone_3. 1 hit.
[Graphical view]
PRINTSiPR00278. PANCHORMONE.
ProDomiPD001267. Pancreatic_hormone-like. 1 hit.
[Graphical view] [Entries sharing at least one domain]
SMARTiSM00309. PAH. 1 hit.
[Graphical view]
PROSITEiPS00265. PANCREATIC_HORMONE_1. 1 hit.
PS50276. PANCREATIC_HORMONE_2. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

A4D158-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MLGNKRLGLS GLTLALSLLV CLGALAEAYP SKPDNPGEDA PAEDMARYYS
60 70 80 90
ALRHYINLIT RQRYGKRSSP ETLISDLLMR ESTENVPRTR LEDPAMW
Length:97
Mass (Da):10,851
Last modified:April 3, 2007 - v1
Checksum:i832CF124321718F2
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AK312156 mRNA. Translation: BAG35090.1.
CH236948 Genomic DNA. Translation: EAL24248.1.
CH471073 Genomic DNA. Translation: EAW93807.1.
RefSeqiNP_000896.1. NM_000905.3.
UniGeneiHs.1832.

Genome annotation databases

GeneIDi4852.
KEGGihsa:4852.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AK312156 mRNA. Translation: BAG35090.1.
CH236948 Genomic DNA. Translation: EAL24248.1.
CH471073 Genomic DNA. Translation: EAW93807.1.
RefSeqiNP_000896.1. NM_000905.3.
UniGeneiHs.1832.

3D structure databases

SMRiA4D158. Positions 29-64.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi9606.ENSP00000242152.

Protocols and materials databases

DNASUi4852.
Structural Biology KnowledgebaseSearch...

Genome annotation databases

GeneIDi4852.
KEGGihsa:4852.

Organism-specific databases

CTDi4852.
PharmGKBiPA255.

Phylogenomic databases

eggNOGiENOG410J0KC. Eukaryota.
ENOG41128I2. LUCA.
HOVERGENiHBG006485.
KOiK05232.
OMAiFEDPSMW.
OrthoDBiEOG091G0ZRE.
PhylomeDBiA4D158.

Miscellaneous databases

ChiTaRSiNPY. human.
GenomeRNAii4852.

Gene expression databases

BgeeiENSG00000122585.

Family and domain databases

CDDicd00126. PAH. 1 hit.
InterProiIPR001955. Pancreatic_hormone-like.
IPR020392. Pancreatic_hormone-like_CS.
[Graphical view]
PANTHERiPTHR10533. PTHR10533. 1 hit.
PfamiPF00159. Hormone_3. 1 hit.
[Graphical view]
PRINTSiPR00278. PANCHORMONE.
ProDomiPD001267. Pancreatic_hormone-like. 1 hit.
[Graphical view] [Entries sharing at least one domain]
SMARTiSM00309. PAH. 1 hit.
[Graphical view]
PROSITEiPS00265. PANCREATIC_HORMONE_1. 1 hit.
PS50276. PANCREATIC_HORMONE_2. 1 hit.
[Graphical view]
ProtoNetiSearch...

Entry informationi

Entry nameiA4D158_HUMAN
AccessioniPrimary (citable) accession number: A4D158
Entry historyi
Integrated into UniProtKB/TrEMBL: April 3, 2007
Last sequence update: April 3, 2007
Last modified: September 7, 2016
This is version 86 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.