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Protein
Submitted name:

Neuropeptide Y

Gene

NPY

Organism
Homo sapiens (Human)
Status
Unreviewed-Annotation score: Annotation score: 2 out of 5-Experimental evidence at transcript leveli

Functioni

GO - Biological processi

Keywordsi

Molecular functionNeuropeptideImported

Names & Taxonomyi

Protein namesi
Submitted name:
Neuropeptide YImported
Submitted name:
cDNA, FLJ92442, Homo sapiens neuropeptide Y (NPY), mRNAImported
Gene namesi
Name:NPYImported
ORF Names:hCG_37313Imported, tcag7.159Imported
OrganismiHomo sapiens (Human)
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo

Subcellular locationi

  • Secreted SAAS annotation

GO - Cellular componenti

Keywords - Cellular componenti

SecretedSAAS annotation

Pathology & Biotechi

Organism-specific databases

PharmGKBiPA255.

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Signal peptidei1 – 28Sequence analysisAdd BLAST28
ChainiPRO_500875444729 – 97Sequence analysisAdd BLAST69

Expressioni

Gene expression databases

BgeeiENSG00000122585.
ExpressionAtlasiA4D158. baseline and differential.

Interactioni

Protein-protein interaction databases

STRINGi9606.ENSP00000242152.

Structurei

3D structure databases

SMRiA4D158.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the NPY family.UniRule annotationSAAS annotation

Keywords - Domaini

SignalSequence analysis

Phylogenomic databases

eggNOGiENOG410J0KC. Eukaryota.
ENOG41128I2. LUCA.
HOVERGENiHBG006485.
KOiK05232.
OMAiFEDPSMW.
OrthoDBiEOG091G0ZRE.
PhylomeDBiA4D158.

Family and domain databases

CDDicd00126. PAH. 1 hit.
InterProiView protein in InterPro
IPR001955. Pancreatic_hormone-like.
IPR020392. Pancreatic_hormone-like_CS.
PANTHERiPTHR10533. PTHR10533. 1 hit.
PfamiView protein in Pfam
PF00159. Hormone_3. 1 hit.
PRINTSiPR00278. PANCHORMONE.
ProDomiView protein in ProDom or Entries sharing at least one domain
PD001267. Pancreatic_hormone-like. 1 hit.
SMARTiView protein in SMART
SM00309. PAH. 1 hit.
PROSITEiView protein in PROSITE
PS00265. PANCREATIC_HORMONE_1. 1 hit.
PS50276. PANCREATIC_HORMONE_2. 1 hit.

Sequencei

Sequence statusi: Complete.

A4D158-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MLGNKRLGLS GLTLALSLLV CLGALAEAYP SKPDNPGEDA PAEDMARYYS
60 70 80 90
ALRHYINLIT RQRYGKRSSP ETLISDLLMR ESTENVPRTR LEDPAMW
Length:97
Mass (Da):10,851
Last modified:April 3, 2007 - v1
Checksum:i832CF124321718F2
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AK312156 mRNA. Translation: BAG35090.1.
CH236948 Genomic DNA. Translation: EAL24248.1.
CH471073 Genomic DNA. Translation: EAW93807.1.
RefSeqiNP_000896.1. NM_000905.3.
UniGeneiHs.1832.

Genome annotation databases

GeneIDi4852.
KEGGihsa:4852.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AK312156 mRNA. Translation: BAG35090.1.
CH236948 Genomic DNA. Translation: EAL24248.1.
CH471073 Genomic DNA. Translation: EAW93807.1.
RefSeqiNP_000896.1. NM_000905.3.
UniGeneiHs.1832.

3D structure databases

SMRiA4D158.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi9606.ENSP00000242152.

Protocols and materials databases

DNASUi4852.
Structural Biology KnowledgebaseSearch...

Genome annotation databases

GeneIDi4852.
KEGGihsa:4852.

Organism-specific databases

CTDi4852.
PharmGKBiPA255.

Phylogenomic databases

eggNOGiENOG410J0KC. Eukaryota.
ENOG41128I2. LUCA.
HOVERGENiHBG006485.
KOiK05232.
OMAiFEDPSMW.
OrthoDBiEOG091G0ZRE.
PhylomeDBiA4D158.

Miscellaneous databases

ChiTaRSiNPY. human.
GenomeRNAii4852.

Gene expression databases

BgeeiENSG00000122585.
ExpressionAtlasiA4D158. baseline and differential.

Family and domain databases

CDDicd00126. PAH. 1 hit.
InterProiView protein in InterPro
IPR001955. Pancreatic_hormone-like.
IPR020392. Pancreatic_hormone-like_CS.
PANTHERiPTHR10533. PTHR10533. 1 hit.
PfamiView protein in Pfam
PF00159. Hormone_3. 1 hit.
PRINTSiPR00278. PANCHORMONE.
ProDomiView protein in ProDom or Entries sharing at least one domain
PD001267. Pancreatic_hormone-like. 1 hit.
SMARTiView protein in SMART
SM00309. PAH. 1 hit.
PROSITEiView protein in PROSITE
PS00265. PANCREATIC_HORMONE_1. 1 hit.
PS50276. PANCREATIC_HORMONE_2. 1 hit.
ProtoNetiSearch...

Entry informationi

Entry nameiA4D158_HUMAN
AccessioniPrimary (citable) accession number: A4D158
Entry historyiIntegrated into UniProtKB/TrEMBL: April 3, 2007
Last sequence update: April 3, 2007
Last modified: January 18, 2017
This is version 90 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.