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  1. 1
    "The sequence of the human genome."
    Venter J.C., Adams M.D., Myers E.W., Li P.W., Mural R.J., Sutton G.G., Smith H.O., Yandell M., Evans C.A., Holt R.A., Gocayne J.D., Amanatides P., Ballew R.M., Huson D.H., Wortman J.R., Zhang Q., Kodira C.D., Zheng X.H.
    , Chen L., Skupski M., Subramanian G., Thomas P.D., Zhang J., Gabor Miklos G.L., Nelson C., Broder S., Clark A.G., Nadeau J., McKusick V.A., Zinder N., Levine A.J., Roberts R.J., Simon M., Slayman C., Hunkapiller M., Bolanos R., Delcher A., Dew I., Fasulo D., Flanigan M., Florea L., Halpern A., Hannenhalli S., Kravitz S., Levy S., Mobarry C., Reinert K., Remington K., Abu-Threideh J., Beasley E., Biddick K., Bonazzi V., Brandon R., Cargill M., Chandramouliswaran I., Charlab R., Chaturvedi K., Deng Z., Di Francesco V., Dunn P., Eilbeck K., Evangelista C., Gabrielian A.E., Gan W., Ge W., Gong F., Gu Z., Guan P., Heiman T.J., Higgins M.E., Ji R.R., Ke Z., Ketchum K.A., Lai Z., Lei Y., Li Z., Li J., Liang Y., Lin X., Lu F., Merkulov G.V., Milshina N., Moore H.M., Naik A.K., Narayan V.A., Neelam B., Nusskern D., Rusch D.B., Salzberg S., Shao W., Shue B., Sun J., Wang Z., Wang A., Wang X., Wang J., Wei M., Wides R., Xiao C., Yan C., Yao A., Ye J., Zhan M., Zhang W., Zhang H., Zhao Q., Zheng L., Zhong F., Zhong W., Zhu S., Zhao S., Gilbert D., Baumhueter S., Spier G., Carter C., Cravchik A., Woodage T., Ali F., An H., Awe A., Baldwin D., Baden H., Barnstead M., Barrow I., Beeson K., Busam D., Carver A., Center A., Cheng M.L., Curry L., Danaher S., Davenport L., Desilets R., Dietz S., Dodson K., Doup L., Ferriera S., Garg N., Gluecksmann A., Hart B., Haynes J., Haynes C., Heiner C., Hladun S., Hostin D., Houck J., Howland T., Ibegwam C., Johnson J., Kalush F., Kline L., Koduru S., Love A., Mann F., May D., McCawley S., McIntosh T., McMullen I., Moy M., Moy L., Murphy B., Nelson K., Pfannkoch C., Pratts E., Puri V., Qureshi H., Reardon M., Rodriguez R., Rogers Y.H., Romblad D., Ruhfel B., Scott R., Sitter C., Smallwood M., Stewart E., Strong R., Suh E., Thomas R., Tint N.N., Tse S., Vech C., Wang G., Wetter J., Williams S., Williams M., Windsor S., Winn-Deen E., Wolfe K., Zaveri J., Zaveri K., Abril J.F., Guigo R., Campbell M.J., Sjolander K.V., Karlak B., Kejariwal A., Mi H., Lazareva B., Hatton T., Narechania A., Diemer K., Muruganujan A., Guo N., Sato S., Bafna V., Istrail S., Lippert R., Schwartz R., Walenz B., Yooseph S., Allen D., Basu A., Baxendale J., Blick L., Caminha M., Carnes-Stine J., Caulk P., Chiang Y.H., Coyne M., Dahlke C., Mays A., Dombroski M., Donnelly M., Ely D., Esparham S., Fosler C., Gire H., Glanowski S., Glasser K., Glodek A., Gorokhov M., Graham K., Gropman B., Harris M., Heil J., Henderson S., Hoover J., Jennings D., Jordan C., Jordan J., Kasha J., Kagan L., Kraft C., Levitsky A., Lewis M., Liu X., Lopez J., Ma D., Majoros W., McDaniel J., Murphy S., Newman M., Nguyen T., Nguyen N., Nodell M., Pan S., Peck J., Peterson M., Rowe W., Sanders R., Scott J., Simpson M., Smith T., Sprague A., Stockwell T., Turner R., Venter E., Wang M., Wen M., Wu D., Wu M., Xia A., Zandieh A., Zhu X.
    Science 291:1304-1351(2001) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Category: Sequences.
    Source: UniProtKB/TrEMBL (unreviewed).

    This publication is cited by 8179 other entries.

  2. 2
    Category: Sequences.
    Source: UniProtKB/TrEMBL (unreviewed).

    This publication is cited by 724 other entries.

  3. 3
    Category: Sequences.
    Source: UniProtKB/TrEMBL (unreviewed).
  4. 4
    Category: Sequences.
    Source: UniProtKB/TrEMBL (unreviewed).
  5. 5
    "Temporal and spatial gene expression patterns after experimental stroke in a rat model and characterization of PC4, a potential regulator of transcription."
    Roth A., Gill R., Certa U.
    Mol. Cell. Neurosci. 22:353-364(2003) [PubMed] [Europe PMC] [Abstract]
    Annotation: PC4/IFRD1 is able to potentiate the transcription of many genes and to inhibit the transcription of few others thus acting as regulator of transcription possibly involved in tissue regenerationImported.
    Source: GeneRIF:3475.

    This publication is mapped to 5 other entries.

  6. 6
    "PC4 coactivates MyoD by relieving the histone deacetylase 4-mediated inhibition of myocyte enhancer factor 2C."
    Micheli L., Leonardi L., Conti F., Buanne P., Canu N., Caruso M., Tirone F.
    Mol. Cell. Biol. 25:2242-2259(2005) [PubMed] [Europe PMC] [Abstract]
    Annotation: Identification of PC4/IFRD1 as a coactivator of MyoD a key master gene of muscle development; PC4/IFRD1 known to be required for muscle differentiation coactivates MyoD by relieving the HDAC4-mediated inhibition of MEF2C as a result of its ability to dose-dependently displace HDAC4 from MEF2C.Imported.
    Source: GeneRIF:3475.

    This publication is mapped to 39 other entries.

  7. 7
    "TIS7 regulation of the beta-catenin/Tcf-4 target gene osteopontin (OPN) is histone deacetylase-dependent."
    Vietor I., Kurzbauer R., Brosch G., Huber L.A.
    J. Biol. Chem. 280:39795-39801(2005) [PubMed] [Europe PMC] [Abstract]
    Annotation: TIS7 a negative regulator of transcriptional activity represses expression of OPN and beta-catenin/Tcf-4 target genesImported.
    Source: GeneRIF:3475.

    This publication is mapped to 76 other entries.

  8. 8
    Annotation: Observational study and genome-wide association study of gene-disease association. (HuGE Navigator); identification of IFRD1 as a modifier of cystic fibrosis lung disease severityImported.
    Source: GeneRIF:3475.

    This publication is mapped to 6 other entries.

  9. 9
    "IFRD1 is a candidate gene for SMNA on chromosome 7q22-q23."
    Brkanac Z., Spencer D., Shendure J., Robertson P.D., Matsushita M., Vu T., Bird T.D., Olson M.V., Raskind W.H.
    Am. J. Hum. Genet. 84:692-697(2009) [PubMed] [Europe PMC] [Abstract]
    Annotation: Sequence conservation animal models and protein structure evaluation support the involvement of IFRD1 in SMNAImported.
    Source: GeneRIF:3475.

    This publication is mapped to 5 other entries.

  10. 10
    "Stress-sensitive regulation of IFRD1 mRNA decay is mediated by an upstream open reading frame."
    Zhao C., Datta S., Mandal P., Xu S., Hamilton T.
    J. Biol. Chem. 285:8552-8562(2010) [PubMed] [Europe PMC] [Abstract]
    Annotation: IFRD1 mRNA decay stress-sensitive regulation is mediated by an upstream open reading frameImported.
    Source: GeneRIF:3475.

    This publication is mapped to 5 other entries.

  11. 11
    "Genomic variation associated with mortality among adults of European and African ancestry with heart failure: the cohorts for heart and aging research in genomic epidemiology consortium."
    Morrison A.C., Felix J.F., Cupples L.A., Glazer N.L., Loehr L.R., Dehghan A., Demissie S., Bis J.C., Rosamond W.D., Aulchenko Y.S., Wang Y.A., Haritunians T., Folsom A.R., Rivadeneira F., Benjamin E.J., Lumley T., Couper D., Stricker B.H.
    , O'Donnell C.J., Rice K.M., Chang P.P., Hofman A., Levy D., Rotter J.I., Fox E.R., Uitterlinden A.G., Wang T.J., Psaty B.M., Willerson J.T., van Duijn C.M., Boerwinkle E., Witteman J.C., Vasan R.S., Smith N.L.
    Circ Cardiovasc Genet 3:248-255(2010) [PubMed] [Europe PMC] [Abstract]
    Annotation: Meta-analysis and genome-wide association study of gene-disease association. (HuGE Navigator)Imported.
    Source: GeneRIF:3475.

    This publication is mapped to 19 other entries.

  12. 12
    "PC4/Tis7/IFRD1 stimulates skeletal muscle regeneration and is involved in myoblast differentiation as a regulator of MyoD and NF-kappaB."
    Micheli L., Leonardi L., Conti F., Maresca G., Colazingari S., Mattei E., Lira S.A., Farioli-Vecchioli S., Caruso M., Tirone F.
    J. Biol. Chem. 286:5691-5707(2011) [PubMed] [Europe PMC] [Abstract]
    Annotation: IFRD1 is an inducer of skeletal muscle regeneration and of satellite cell amplification by regulating MyoD and NF-kB.Imported.
    Source: GeneRIF:3475.

    This publication is mapped to 7 other entries.

  13. 13
    "The BTB and CNC homology 1 (BACH1) target genes are involved in the oxidative stress response and in control of the cell cycle."
    Warnatz H.J., Schmidt D., Manke T., Piccini I., Sultan M., Borodina T., Balzereit D., Wruck W., Soldatov A., Vingron M., Lehrach H., Yaspo M.L.
    J. Biol. Chem. 286:23521-23532(2011) [PubMed] [Europe PMC] [Abstract]
    Annotation: IFRD1 is a target gene of the BACH1 transcription factor according to ChIP-seq analysis in HEK 293 cells.Imported.
    Source: GeneRIF:3475.

    This publication is mapped to 199 other entries.

  14. 14
    "Reduced expression of Tis7/IFRD1 protein in murine and human cystic fibrosis airway epithelial cell models homozygous for the F508del-CFTR mutation."
    Blanchard E., Marie S., Riffault L., Bonora M., Tabary O., Clement A., Jacquot J.
    Biochem. Biophys. Res. Commun. 411:471-476(2011) [PubMed] [Europe PMC] [Abstract]
    Annotation: This work provides evidence for the first time of reduced level of IFRD1 protein in murine and human F508del-CFTR airway epithelial cell models.Imported.
    Source: GeneRIF:3475.

    This publication is mapped to 6 other entries.

  15. 15
    "Expression and regulation of interferon-related development regulator-1 in cystic fibrosis neutrophils."
    Hector A., Kormann M., Kammermeier J., Burdi S., Marcos V., Rieber N., Mays L., Illig T., Klopp N., Falkenstein F., Kappler M., Riethmueller J., Graepler-Mainka U., Stern M., Eickmeier O., Serve F., Zielen S., Doring G., Griese M., Hartl D.
    Am. J. Respir. Cell Mol. Biol. 48:71-77(2013) [PubMed] [Europe PMC] [Abstract]
    Annotation: IFRD1 expression is systemically up-regulated in CF neutrophils is linked to the production of ROS and is modulated by chemokines in CF airway fluids depending on the IFRD1 genotype.Imported.
    Source: GeneRIF:3475.

    This publication is mapped to 5 other entries.

  16. 16
    "Early gene regulation by nerve growth factor in PC12 cells: induction of an interferon-related gene."
    Tirone F., Shooter E.M.
    Proc. Natl. Acad. Sci. U.S.A. 86:2088-2092(1989) [PubMed] [Europe PMC] [Abstract]
    Annotation: This reference shows the cloning and the sequence of the original IFRD1 homolog isolated in rat as nerve growth factor-inducible immediate early gene (named PC4); This reference (Tirone and Shooter 1989) shows the cloning and the sequence of the original IFRD1 homolog isolated in rat as NGF-inducible immediate early gene (named PC4).Imported.
    Source: GeneRIF:3475.

    This publication is mapped to 5 other entries.

  17. 17
    "IFRD1 polymorphisms and gastric cancer risk in a Chinese population."
    Xu R., Peng C., Xiao S., Zhuang W.
    Med. Oncol. 31:135-135(2014) [PubMed] [Europe PMC] [Abstract]
    Annotation: Studied the association between IFRD1 polymorphisms and gastric cancer in a Chinese population.Imported.
    Source: GeneRIF:3475.

    This publication is mapped to 5 other entries.

  18. 18
    "Transcription cofactor PC4 plays essential roles in collaboration with the small subunit of general transcription factor TFIIE."
    Akimoto Y., Yamamoto S., Iida S., Hirose Y., Tanaka A., Hanaoka F., Ohkuma Y.
    Genes Cells 19:879-890(2014) [PubMed] [Europe PMC] [Abstract]
    Annotation: PC4 plays essential roles in the transition step from transcription initiation to elongation by binding to melted DNA in collaboration with TFIIEbeta.Imported.
    Source: GeneRIF:3475.

    This publication is mapped to 6 other entries.

  19. 19
    "Investigation of association between hip osteoarthritis susceptibility loci and radiographic proximal femur shape."
    arcOGEN Consortium
    Lindner C., Thiagarajah S., Wilkinson J.M., Panoutsopoulou K., Day-Williams A.G., Cootes T.F., Wallis G.A., Loughlin J., Arden N., Birrell F., Carr A., Chapman K., Deloukas P., Doherty M., McCaskie A., Ollier W.E., Rai A., Ralston S.H.
    , Spector T.D., Valdes A.M., Wallis G.A., Wilkinson J.M., Zeggini E.
    Arthritis Rheumatol 67:2076-2084(2015) [PubMed] [Europe PMC] [Abstract]
    Annotation: rs5009270 may contribute to hip OA susceptibility by altering proximal femur shape.Imported.
    Source: GeneRIF:3475.

    This publication is mapped to 16 other entries.

  20. 20
    "The interferon-related developmental regulator 1 is used by human papillomavirus to suppress NFkappaB activation."
    Tummers B., Goedemans R., Pelascini L.P., Jordanova E.S., van Esch E.M., Meyers C., Melief C.J., Boer J.M., van der Burg S.H.
    Nat Commun 6:6537-6537(2015) [PubMed] [Europe PMC] [Abstract]
    Annotation: study reveals an EGFR-IFRD1-mediated viral immune evasion mechanism which can also be exploited by cancer cellsImported.
    Source: GeneRIF:3475.

    This publication is mapped to 5 other entries.

  21. 21
    "IFRD1 gene polymorphisms are associated with nasal polyposis in cystic fibrosis patients."
    Baldan A., Lo Presti A.R., Belpinati F., Castellani C., Bettin M.D., Xumerle L., Pignatti P.R., Malerba G., Bombieri C.
    Rhinology 53:359-364(2015) [PubMed] [Europe PMC] [Abstract]
    Annotation: rs7817 polymorphism associated with nasal polyposis in cystic fibrosis patientsImported.
    Source: GeneRIF:3475.

    This publication is mapped to 5 other entries.

  22. 22
    "Uncovering potential key genes associated with the pathogenesis of asthma: A microarray analysis of asthma-relevant tissues."
    Guan Y., Jin X., Liu X., Huang Y., Wang M., Li X.
    Allergol Immunopathol (Madr) 45:152-159(2017) [PubMed] [Europe PMC] [Abstract]
    Annotation: this study shows that IFRD1 gene may be associated with pathogenesis of asthmaImported.
    Source: GeneRIF:3475.

    This publication is mapped to 31 other entries.

  23. 23
    "Characterization of TIS7, a gene induced in Swiss 3T3 cells by the tumor promoter tetradecanoyl phorbol acetate."
    Varnum B.C., Lim R.W., Herschman H.R.
    Oncogene 4:1263-1265(1989) [PubMed] [Europe PMC] [Abstract]
    Annotation: This reference shows the cloning and the sequence of the original IFRD1 homolog isolated in mouse as TPA-inducible immediate early gene (named Tis7).Imported.
    Source: GeneRIF:3475.

    This publication is mapped to 11 other entries.

  24. 24
    "Inhibition of differentiation in myoblasts deprived of the interferon-related protein PC4."
    Guardavaccaro D., Ciotti M.T., Schafer B.W., Montagnoli A., Tirone F.
    Cell Growth Differ. 6:159-169(1995) [PubMed] [Europe PMC] [Abstract]
    Annotation: In the absence of PC4/IFRD1 skeletal muscle differentiation is defective; Functional ablation of PC4/IFRD1 in myoblast cells by sense and antisense strategies as well as by microinjection of PC4/IFRD1 antibodies inhibits differentiation.Imported.
    Source: GeneRIF:3475.

    This publication is mapped to 6 other entries.

  25. 25
    "Cloning of the human interferon-related developmental regulator (IFRD1) gene coding for the PC4 protein, a member of a novel family of developmentally regulated genes."
    Buanne P., Incerti B., Guardavaccaro D., Avvantaggiato V., Simeone A., Tirone F.
    Genomics 51:233-242(1998) [PubMed] [Europe PMC] [Abstract]
    Annotation: Identification of the IFRD gene family comprising the two genes PC4 / Tis7 / IFRD1 and SKMc15 / IFRD2 and in situ-hybridization analysis of their expression during developmentsImported.
    Source: GeneRIF:3475.

    This publication is mapped to 21 other entries.

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