Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Protein

Catalase-peroxidase

Gene

katG

Organism
Synechococcus sp. (strain WH7805)
Status
Unreviewed-Annotation score: Annotation score: 3 out of 5-Protein inferred from homologyi

Functioni

Bifunctional enzyme with both catalase and broad-spectrum peroxidase activity.UniRule annotationSAAS annotation

Catalytic activityi

2 H2O2 = O2 + 2 H2O.UniRule annotationSAAS annotation
Donor + H2O2 = oxidized donor + 2 H2O.UniRule annotationSAAS annotation

Cofactori

heme bUniRule annotation

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Sitei92Transition state stabilizerUniRule annotation1
Active sitei96Proton acceptorUniRule annotation1
Metal bindingi259Iron (heme axial ligand)UniRule annotation1

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Keywords - Molecular functioni

Oxidoreductase, Peroxidase

Keywords - Biological processi

Hydrogen peroxideUniRule annotationSAAS annotation

Keywords - Ligandi

HemeUniRule annotationSAAS annotation, Iron, Metal-binding

Protein family/group databases

PeroxiBasei6251. SspCP01_WH7805.

Names & Taxonomyi

Protein namesi
Recommended name:
Catalase-peroxidaseUniRule annotation (EC:1.11.1.21UniRule annotation)
Short name:
CPUniRule annotation
Alternative name(s):
Peroxidase/catalaseUniRule annotation
Gene namesi
Name:katGUniRule annotation
ORF Names:WH7805_00345Imported
OrganismiSynechococcus sp. (strain WH7805)Imported
Taxonomic identifieri59931 [NCBI]
Taxonomic lineageiBacteriaCyanobacteriaSynechococcalesSynechococcaceaeSynechococcus
Proteomesi
  • UP000001224 Componenti: Unassembled WGS sequence

PTM / Processingi

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Cross-linki95 ↔ 218Tryptophyl-tyrosyl-methioninium (Trp-Tyr) (with M-244)UniRule annotation
Cross-linki218 ↔ 244Tryptophyl-tyrosyl-methioninium (Tyr-Met) (with W-95)UniRule annotation

Post-translational modificationi

The covalent Trp-Tyr-Met adduct is important for the catalase, but not the peroxidase activity of the enzyme.UniRule annotation

Interactioni

Protein-protein interaction databases

STRINGi59931.WH7805_00345.

Structurei

3D structure databases

ProteinModelPortaliA4CXI4.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini129 – 426PEROXIDASE_4InterPro annotationAdd BLAST298
Domaini453 – 731PEROXIDASE_4InterPro annotationAdd BLAST279

Sequence similaritiesi

Belongs to the peroxidase family. Peroxidase/catalase subfamily.UniRule annotationSAAS annotation

Phylogenomic databases

eggNOGiENOG4105C1X. Bacteria.
COG0376. LUCA.
OrthoDBiPOG091H05R1.
PhylomeDBiA4CXI4.

Family and domain databases

HAMAPiMF_01961. Catal_peroxid. 1 hit.
InterProiIPR000763. Catalase_peroxidase.
IPR010255. Haem_peroxidase.
IPR002016. Haem_peroxidase_pln/fun/bac.
IPR019794. Peroxidases_AS.
IPR019793. Peroxidases_heam-ligand_BS.
[Graphical view]
PfamiPF00141. peroxidase. 2 hits.
[Graphical view]
PRINTSiPR00460. BPEROXIDASE.
PR00458. PEROXIDASE.
SUPFAMiSSF48113. SSF48113. 2 hits.
TIGRFAMsiTIGR00198. cat_per_HPI. 1 hit.
PROSITEiPS00435. PEROXIDASE_1. 1 hit.
PS00436. PEROXIDASE_2. 1 hit.
PS50873. PEROXIDASE_4. 2 hits.
[Graphical view]

Sequencei

Sequence statusi: Complete.

A4CXI4-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MSDLKCPFSG HTGAVTPAGR TDNSDWWPNQ IDLGILHQHH PASNPLGDDF
60 70 80 90 100
DYPSAFTALD YSALKADLQA LMTDSQDWWP ADWGHYGALF IRLAWHSAGT
110 120 130 140 150
YRTGDGRGGA GHGNQRFAPL NSWPDNTNLD KARRLLWPVK RKYGNAISWA
160 170 180 190 200
DLIILSGNVA LESMGFRTFG FAGGRVDIWQ PEEDVFWGTE TGWLSDERHN
210 220 230 240 250
EKGELEQPLA AVQMGLIYVN PEGPGGEPDP VASGRDVRET FARMGMTVEE
260 270 280 290 300
TVALVAGGHT FGKCHGAAPD SNLGAEPEGA ALHEQGLGWR NSYETGKGEH
310 320 330 340 350
TISSGIEGAW KPNPTRWDQG YFQMMFTYDW ELTKSPAGAW QWTAKDVKPE
360 370 380 390 400
HMVPDAHVAG KSSAPIMTTA DLSLRHDAIM EPVARRFYQD QEAFADAFAR
410 420 430 440 450
AWFKLTHRDL GPRALYLGQE VPEEVQIWQD PIPDVNHALI DDADISNLKQ
460 470 480 490 500
QILASGQSMS ALVATAWASA STFRGSDRRG GANGGRIRLL PQRTWEVNEP
510 520 530 540 550
EQLNGVLAAL ETIQSEFNSS RTDGKSVSIA DLVVLGGCAA VEKAAADGGQ
560 570 580 590 600
SVMVPFSPGR TDAGPEQTDT ASFNVLKPLA DGFRNWKRSG LPLRAEELLI
610 620 630 640 650
DQAQLLTLSA PEMTVLLAGL RVLGANTGGN RQGVFTTNVG VLSNDFCVNL
660 670 680 690 700
LDMTTRWTPT NEAQDAYVGH DSASGAERWS ASRADLVFGS NSQLRAIVEV
710 720 730
YAQNDGSSRF VADFVKAWVK VMELDRFDLH G
Length:731
Mass (Da):79,793
Last modified:April 3, 2007 - v1
Checksum:iF6B8DFD2C8278632
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AAOK01000006 Genomic DNA. Translation: EAR17517.1.
RefSeqiWP_006040885.1. NZ_CH724168.1.

Genome annotation databases

EnsemblBacteriaiEAR17517; EAR17517; WH7805_00345.
PATRICi29899796. VBISynSp124776_0066.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AAOK01000006 Genomic DNA. Translation: EAR17517.1.
RefSeqiWP_006040885.1. NZ_CH724168.1.

3D structure databases

ProteinModelPortaliA4CXI4.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi59931.WH7805_00345.

Protein family/group databases

PeroxiBasei6251. SspCP01_WH7805.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiEAR17517; EAR17517; WH7805_00345.
PATRICi29899796. VBISynSp124776_0066.

Phylogenomic databases

eggNOGiENOG4105C1X. Bacteria.
COG0376. LUCA.
OrthoDBiPOG091H05R1.
PhylomeDBiA4CXI4.

Family and domain databases

HAMAPiMF_01961. Catal_peroxid. 1 hit.
InterProiIPR000763. Catalase_peroxidase.
IPR010255. Haem_peroxidase.
IPR002016. Haem_peroxidase_pln/fun/bac.
IPR019794. Peroxidases_AS.
IPR019793. Peroxidases_heam-ligand_BS.
[Graphical view]
PfamiPF00141. peroxidase. 2 hits.
[Graphical view]
PRINTSiPR00460. BPEROXIDASE.
PR00458. PEROXIDASE.
SUPFAMiSSF48113. SSF48113. 2 hits.
TIGRFAMsiTIGR00198. cat_per_HPI. 1 hit.
PROSITEiPS00435. PEROXIDASE_1. 1 hit.
PS00436. PEROXIDASE_2. 1 hit.
PS50873. PEROXIDASE_4. 2 hits.
[Graphical view]
ProtoNetiSearch...

Entry informationi

Entry nameiA4CXI4_SYNPV
AccessioniPrimary (citable) accession number: A4CXI4
Entry historyi
Integrated into UniProtKB/TrEMBL: April 3, 2007
Last sequence update: April 3, 2007
Last modified: November 30, 2016
This is version 68 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Caution

The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.Imported

Keywords - Technical termi

Complete proteome, Reference proteomeImported

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.