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A4CP91 (A4CP91_ROBBH) Unreviewed, UniProtKB/TrEMBL

Last modified June 11, 2014. Version 59. Feed History...

Clusters with 100%, 90%, 50% identity | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein namesRecommended name:
D-alanine--D-alanine ligase HAMAP-Rule MF_00047

EC=6.3.2.4 HAMAP-Rule MF_00047
Alternative name(s):
D-Ala-D-Ala ligase HAMAP-Rule MF_00047
D-alanylalanine synthetase HAMAP-Rule MF_00047
Gene names
Name:ddl HAMAP-Rule MF_00047
Ordered Locus Names:RB2501_02270 EMBL EAR14212.1
OrganismRobiginitalea biformata (strain ATCC BAA-864 / HTCC2501 / KCTC 12146) [Complete proteome] [HAMAP] EMBL EAR14212.1
Taxonomic identifier313596 [NCBI]
Taxonomic lineageBacteriaBacteroidetesFlavobacteriiaFlavobacterialesFlavobacteriaceaeRobiginitalea

Protein attributes

Sequence length329 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

Cell wall formation By similarity. HAMAP-Rule MF_00047 SAAS SAAS011095

Catalytic activity

ATP + 2 D-alanine = ADP + phosphate + D-alanyl-D-alanine. HAMAP-Rule MF_00047 SAAS SAAS011095

Cofactor

Binds 2 magnesium or manganese ions per subunit By similarity. HAMAP-Rule MF_00047 SAAS SAAS011095

Pathway

Cell wall biogenesis; peptidoglycan biosynthesis. HAMAP-Rule MF_00047 SAAS SAAS011095

Subcellular location

Cytoplasm By similarity HAMAP-Rule MF_00047 SAAS SAAS011095.

Sequence similarities

Belongs to the D-alanine--D-alanine ligase family. HAMAP-Rule MF_00047

Contains 1 ATP-grasp domain. HAMAP-Rule MF_00047

Contains ATP-grasp domain. SAAS SAAS011095

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Regions

Domain123 – 322200ATP-grasp By similarity HAMAP-Rule MF_00047
Nucleotide binding151 – 20656ATP By similarity HAMAP-Rule MF_00047

Sites

Metal binding2771Magnesium or manganese 1 By similarity HAMAP-Rule MF_00047
Metal binding2891Magnesium or manganese 1 By similarity HAMAP-Rule MF_00047
Metal binding2891Magnesium or manganese 2 By similarity HAMAP-Rule MF_00047
Metal binding2911Magnesium or manganese 2 By similarity HAMAP-Rule MF_00047

Sequences

Sequence LengthMass (Da)Tools
A4CP91 [UniParc].

Last modified April 3, 2007. Version 1.
Checksum: 668C4C03D8BAC8E7

FASTA32936,164
        10         20         30         40         50         60 
MGSTKKIAVI MGGYSSEYEI SLKSGEVVCK WLDRDQYDPY RILIRRDKWV MLGDSGREYP 

        70         80         90        100        110        120 
VSRHDFSVEL EDGTLRFDCV FNAIHGTPGE NGLMQAYFEL IGMPQTSCGF YQAAVTFNKR 

       130        140        150        160        170        180 
DLLGILKSAG VPAARSYHLD RGQELNQQAI LDAVGLPCFV KANRAGSSFG VSLVREASGL 

       190        200        210        220        230        240 
QAAVENALKE DDEILIEAAL QGTEVSVGVI RYQGATRVLP ITEIVSENDF FDYQAKYEGK 

       250        260        270        280        290        300 
SREITPARIP EDTAEKVREL AARIYDRLRM TGYSRSEFIL VDGEPHLLEV NTTPGLTEAS 

       310        320 
ILPQQAACAG ISLTELFGSA IADALDKNG 

« Hide

References

[1]"Complete genome sequence of Robiginitalea biformata HTCC2501."
Oh H.M., Giovannoni S.J., Lee K., Ferriera S., Johnson J., Cho J.C.
J. Bacteriol. 191:7144-7145(2009) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: ATCC BAA-864 / HTCC2501 / KCTC 12146.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
CP001712 Genomic DNA. Translation: EAR14212.1.
RefSeqYP_003196674.1. NC_013222.1.

3D structure databases

ProteinModelPortalA4CP91.
ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

STRING313596.RB2501_02270.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaEAR14212; EAR14212; RB2501_02270.
GeneID8457402.
KEGGrbi:RB2501_02270.
PATRIC23337403. VBIRobBif55773_2946.

Organism-specific databases

CMRSearch...

Phylogenomic databases

eggNOGCOG1181.
HOGENOMHOG000011592.
KOK01921.
OrthoDBEOG6ND0KB.

Enzyme and pathway databases

BioCycRBIF313596:GH7G-3050-MONOMER.
UniPathwayUPA00219.

Family and domain databases

Gene3D3.30.1490.20. 1 hit.
3.30.470.20. 1 hit.
3.40.50.20. 1 hit.
HAMAPMF_00047. Dala_Dala_lig.
InterProIPR011761. ATP-grasp.
IPR013815. ATP_grasp_subdomain_1.
IPR013816. ATP_grasp_subdomain_2.
IPR000291. D-Ala_lig_Van_CS.
IPR005905. D_ala_D_ala.
IPR011095. Dala_Dala_lig_C.
IPR011127. Dala_Dala_lig_N.
IPR016185. PreATP-grasp_dom.
[Graphical view]
PANTHERPTHR23132. PTHR23132. 1 hit.
PfamPF07478. Dala_Dala_lig_C. 1 hit.
PF01820. Dala_Dala_lig_N. 1 hit.
[Graphical view]
SUPFAMSSF52440. SSF52440. 1 hit.
TIGRFAMsTIGR01205. D_ala_D_alaTIGR. 1 hit.
PROSITEPS50975. ATP_GRASP. 1 hit.
PS00843. DALA_DALA_LIGASE_1. 1 hit.
PS00844. DALA_DALA_LIGASE_2. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameA4CP91_ROBBH
AccessionPrimary (citable) accession number: A4CP91
Entry history
Integrated into UniProtKB/TrEMBL: April 3, 2007
Last sequence update: April 3, 2007
Last modified: June 11, 2014
This is version 59 of the entry and version 1 of the sequence. [Complete history]
Entry statusUnreviewed (UniProtKB/TrEMBL)