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A4CIF1

- A4CIF1_ROBBH

UniProt

A4CIF1 - A4CIF1_ROBBH

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Protein
Thymidine kinase
Gene
tdk, RB2501_07405
Organism
Robiginitalea biformata (strain ATCC BAA-864 / HTCC2501 / KCTC 12146)
Status
Unreviewed - Annotation score: 2 out of 5 - Protein inferred from homologyi

Functioni

Catalytic activityi

ATP + thymidine = ADP + thymidine 5'-phosphate.UniRule annotationSAAS annotations

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Active sitei94 – 941Proton acceptor By similarityUniRule annotation

Regions

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Nucleotide bindingi21 – 288ATP By similarityUniRule annotation
Nucleotide bindingi93 – 964ATP By similarityUniRule annotation

GO - Molecular functioni

  1. ATP binding Source: UniProtKB-HAMAP
  2. thymidine kinase activity Source: UniProtKB-HAMAP
Complete GO annotation...

GO - Biological processi

  1. DNA replication Source: UniProtKB-KW
Complete GO annotation...

Keywords - Molecular functioni

KinaseUniRule annotationSAAS annotationsImported, Transferase

Keywords - Biological processi

DNA synthesisUniRule annotationSAAS annotations

Keywords - Ligandi

ATP-bindingUniRule annotationSAAS annotations, Nucleotide-binding

Enzyme and pathway databases

BioCyciRBIF313596:GH7G-830-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
Thymidine kinaseUniRule annotation (EC:2.7.1.21UniRule annotation)
Gene namesi
Name:tdkUniRule annotation
Ordered Locus Names:RB2501_07405Imported
OrganismiRobiginitalea biformata (strain ATCC BAA-864 / HTCC2501 / KCTC 12146)Imported
Taxonomic identifieri313596 [NCBI]
Taxonomic lineageiBacteriaBacteroidetesFlavobacteriiaFlavobacterialesFlavobacteriaceaeRobiginitalea
ProteomesiUP000009049: Chromosome

Subcellular locationi

Cytoplasm By similarity UniRule annotation

GO - Cellular componenti

  1. cytoplasm Source: UniProtKB-SubCell
Complete GO annotation...

Keywords - Cellular componenti

CytoplasmUniRule annotation

Interactioni

Subunit structurei

Homotetramer By similarity.UniRule annotation

Protein-protein interaction databases

STRINGi313596.RB2501_07405.

Structurei

3D structure databases

ProteinModelPortaliA4CIF1.

Family & Domainsi

Sequence similaritiesi

Belongs to the thymidine kinase family.UniRule annotation

Phylogenomic databases

eggNOGiCOG1435.
HOGENOMiHOG000076390.
KOiK00857.
OrthoDBiEOG69D3J2.

Family and domain databases

HAMAPiMF_00124. Thymidine_kinase.
InterProiIPR027417. P-loop_NTPase.
IPR001267. Thymidine_kinase.
IPR020634. Thymidine_kinase_subgr.
[Graphical view]
PANTHERiPTHR11441. PTHR11441. 1 hit.
PfamiPF00265. TK. 1 hit.
[Graphical view]
PIRSFiPIRSF035805. TK_cell. 1 hit.
SUPFAMiSSF52540. SSF52540. 1 hit.

Sequencei

Sequence statusi: Complete.

A4CIF1-1 [UniParc]FASTAAdd to Basket

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MFLENTVNPK EQFGWIEVIC GSMFSGKTEE LIRRLRRAQF ARQKVEIFKP    50
IVDTRYHEDY VVSHDENEIR STPVPAAANI RLLADNCDVV GIDEAQFFDD 100
EIVTVCNDLA NKGVRVVVAG LDMDFKGNPF GPMPALMATA EYVTKVHAIC 150
TRTGNLANYS YRKSRNDRLV LLGETEEYEP LSRGAFYKAM LTEKISKLEV 200
NEPEVLPSKK SENASKP 217
Length:217
Mass (Da):24,511
Last modified:April 3, 2007 - v1
Checksum:iC3E7A7A3AA7A9D73
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
CP001712 Genomic DNA. Translation: EAR16709.1.
RefSeqiYP_003194488.1. NC_013222.1.

Genome annotation databases

EnsemblBacteriaiEAR16709; EAR16709; RB2501_07405.
GeneIDi8455182.
KEGGirbi:RB2501_07405.
PATRICi23332997. VBIRobBif55773_0777.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
CP001712 Genomic DNA. Translation: EAR16709.1 .
RefSeqi YP_003194488.1. NC_013222.1.

3D structure databases

ProteinModelPortali A4CIF1.
ModBasei Search...

Protein-protein interaction databases

STRINGi 313596.RB2501_07405.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblBacteriai EAR16709 ; EAR16709 ; RB2501_07405 .
GeneIDi 8455182.
KEGGi rbi:RB2501_07405.
PATRICi 23332997. VBIRobBif55773_0777.

Phylogenomic databases

eggNOGi COG1435.
HOGENOMi HOG000076390.
KOi K00857.
OrthoDBi EOG69D3J2.

Enzyme and pathway databases

BioCyci RBIF313596:GH7G-830-MONOMER.

Family and domain databases

HAMAPi MF_00124. Thymidine_kinase.
InterProi IPR027417. P-loop_NTPase.
IPR001267. Thymidine_kinase.
IPR020634. Thymidine_kinase_subgr.
[Graphical view ]
PANTHERi PTHR11441. PTHR11441. 1 hit.
Pfami PF00265. TK. 1 hit.
[Graphical view ]
PIRSFi PIRSF035805. TK_cell. 1 hit.
SUPFAMi SSF52540. SSF52540. 1 hit.
ProtoNeti Search...

Publicationsi

  1. "Complete genome sequence of Robiginitalea biformata HTCC2501."
    Oh H.M., Giovannoni S.J., Lee K., Ferriera S., Johnson J., Cho J.C.
    J. Bacteriol. 191:7144-7145(2009) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: ATCC BAA-864 / HTCC2501 / KCTC 12146.

Entry informationi

Entry nameiA4CIF1_ROBBH
AccessioniPrimary (citable) accession number: A4CIF1
Entry historyi
Integrated into UniProtKB/TrEMBL: April 3, 2007
Last sequence update: April 3, 2007
Last modified: June 11, 2014
This is version 54 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome

External Data

Dasty 3

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