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Protein

Xylose isomerase

Gene

xylA

Organism
Robiginitalea biformata (strain ATCC BAA-864 / HTCC2501 / KCTC 12146)
Status
Unreviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

Catalytic activityi

D-xylopyranose = D-xylulose.UniRule annotationSAAS annotation

Cofactori

Mg2+UniRule annotationNote: Binds 2 magnesium ions per subunit.UniRule annotation

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Active sitei106 – 1061UniRule annotation
Active sitei109 – 1091UniRule annotation
Metal bindingi237 – 2371Magnesium 1UniRule annotation
Metal bindingi273 – 2731Magnesium 1UniRule annotation
Metal bindingi273 – 2731Magnesium 2UniRule annotation
Metal bindingi276 – 2761Magnesium 2UniRule annotation
Metal bindingi301 – 3011Magnesium 1UniRule annotation
Metal bindingi312 – 3121Magnesium 2UniRule annotation
Metal bindingi314 – 3141Magnesium 2UniRule annotation
Metal bindingi344 – 3441Magnesium 1UniRule annotation

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Keywords - Molecular functioni

IsomeraseUniRule annotation

Keywords - Biological processi

Carbohydrate metabolism, Pentose shuntUniRule annotation, Xylose metabolismUniRule annotation

Keywords - Ligandi

MagnesiumUniRule annotationSAAS annotation, Metal-bindingUniRule annotation

Enzyme and pathway databases

BioCyciRBIF313596:GH7G-252-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
Xylose isomeraseUniRule annotation (EC:5.3.1.5UniRule annotation)
Gene namesi
Name:xylAUniRule annotation
Ordered Locus Names:RB2501_04540Imported
OrganismiRobiginitalea biformata (strain ATCC BAA-864 / HTCC2501 / KCTC 12146)Imported
Taxonomic identifieri313596 [NCBI]
Taxonomic lineageiBacteriaBacteroidetesFlavobacteriiaFlavobacterialesFlavobacteriaceaeRobiginitalea
ProteomesiUP000009049 Componenti: Chromosome

Subcellular locationi

  • Cytoplasm UniRule annotationSAAS annotation

GO - Cellular componenti

Complete GO annotation...

Keywords - Cellular componenti

CytoplasmUniRule annotationSAAS annotation

Interactioni

Subunit structurei

Homotetramer.UniRule annotationSAAS annotation

Protein-protein interaction databases

STRINGi313596.RB2501_04540.

Structurei

3D structure databases

ProteinModelPortaliA4CGS8.
SMRiA4CGS8. Positions 7-441.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the xylose isomerase family.UniRule annotation

Phylogenomic databases

eggNOGiCOG2115.
HOGENOMiHOG000252293.
KOiK01805.
OrthoDBiEOG62NX4R.

Family and domain databases

Gene3Di3.20.20.150. 1 hit.
HAMAPiMF_00455. Xylose_isom_A.
InterProiIPR013022. Xyl_isomerase-like_TIM-brl.
IPR013452. Xylose_isom_bac.
IPR001998. Xylose_isomerase.
[Graphical view]
PfamiPF01261. AP_endonuc_2. 1 hit.
[Graphical view]
PRINTSiPR00688. XYLOSISMRASE.
SUPFAMiSSF51658. SSF51658. 1 hit.
TIGRFAMsiTIGR02630. xylose_isom_A. 1 hit.
PROSITEiPS51415. XYLOSE_ISOMERASE. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

A4CGS8-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MITTGDKEYF KNIGKIPFEG KESDNPLAFK YYDENQKVGD KTMKEHFRFA
60 70 80 90 100
VCYWHTFTGL GADPFGAPTQ QFPWLENSDP VQQAKDKMDA AFEFITKIGA
110 120 130 140 150
PYYCFHDYDL IAEGPTLAES ERRLDIITDY AREKMDASGV KLLWGTANCF
160 170 180 190 200
GNPRYMNGAA TNPDFKVLAA AGAQVKNALD ATIKLDGENY VFWGGREGYM
210 220 230 240 250
SLLNTDMKRE QDHMARFLHM ARDYARKQGF KGVFFIEPKP MEPTKHQYDF
260 270 280 290 300
DSATVLAFLS KYDLLDDFKL NIEVNHATLA QHTFEHELQV AADNGLLGSI
310 320 330 340 350
DANRGDYQNG WDTDQFPVDV YELTQAMLVI LEAGGFQGGG VNFDAKIRRN
360 370 380 390 400
STDLEDIFYA HIGGMDAFAR ALLAAHAVRT QSDFLKMRKD RYASFDSGKG
410 420 430 440
AEFEAGKLSL EDLHKFAGAN QEIPRTSGRQ ELYENIINQF I
Length:441
Mass (Da):49,844
Last modified:April 3, 2007 - v1
Checksum:i5F8537C7E025450B
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP001712 Genomic DNA. Translation: EAR16136.1.
RefSeqiWP_012813831.1. NC_013222.1.
YP_003193917.1. NC_013222.1.

Genome annotation databases

EnsemblBacteriaiEAR16136; EAR16136; RB2501_04540.
KEGGirbi:RB2501_04540.
PATRICi23331909. VBIRobBif55773_0239.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP001712 Genomic DNA. Translation: EAR16136.1.
RefSeqiWP_012813831.1. NC_013222.1.
YP_003193917.1. NC_013222.1.

3D structure databases

ProteinModelPortaliA4CGS8.
SMRiA4CGS8. Positions 7-441.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi313596.RB2501_04540.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiEAR16136; EAR16136; RB2501_04540.
KEGGirbi:RB2501_04540.
PATRICi23331909. VBIRobBif55773_0239.

Phylogenomic databases

eggNOGiCOG2115.
HOGENOMiHOG000252293.
KOiK01805.
OrthoDBiEOG62NX4R.

Enzyme and pathway databases

BioCyciRBIF313596:GH7G-252-MONOMER.

Family and domain databases

Gene3Di3.20.20.150. 1 hit.
HAMAPiMF_00455. Xylose_isom_A.
InterProiIPR013022. Xyl_isomerase-like_TIM-brl.
IPR013452. Xylose_isom_bac.
IPR001998. Xylose_isomerase.
[Graphical view]
PfamiPF01261. AP_endonuc_2. 1 hit.
[Graphical view]
PRINTSiPR00688. XYLOSISMRASE.
SUPFAMiSSF51658. SSF51658. 1 hit.
TIGRFAMsiTIGR02630. xylose_isom_A. 1 hit.
PROSITEiPS51415. XYLOSE_ISOMERASE. 1 hit.
[Graphical view]
ProtoNetiSearch...

Publicationsi

  1. "Complete genome sequence of Robiginitalea biformata HTCC2501."
    Oh H.M., Giovannoni S.J., Lee K., Ferriera S., Johnson J., Cho J.C.
    J. Bacteriol. 191:7144-7145(2009) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: ATCC BAA-864 / HTCC2501 / KCTC 12146Imported.

Entry informationi

Entry nameiA4CGS8_ROBBH
AccessioniPrimary (citable) accession number: A4CGS8
Entry historyi
Integrated into UniProtKB/TrEMBL: April 3, 2007
Last sequence update: April 3, 2007
Last modified: May 27, 2015
This is version 60 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported

External Data

Dasty 3

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into Uniref entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.