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Protein

Xylose isomerase

Gene

xylA

Organism
Robiginitalea biformata (strain ATCC BAA-864 / HTCC2501 / KCTC 12146)
Status
Unreviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

Catalytic activityi

D-xylopyranose = D-xylulose.UniRule annotationSAAS annotation

Cofactori

Mg2+UniRule annotationNote: Binds 2 magnesium ions per subunit.UniRule annotation

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Active sitei106UniRule annotation1
Active sitei109UniRule annotation1
Metal bindingi237Magnesium 1UniRule annotation1
Metal bindingi273Magnesium 1UniRule annotation1
Metal bindingi273Magnesium 2UniRule annotation1
Metal bindingi276Magnesium 2UniRule annotation1
Metal bindingi301Magnesium 1UniRule annotation1
Metal bindingi312Magnesium 2UniRule annotation1
Metal bindingi314Magnesium 2UniRule annotation1
Metal bindingi344Magnesium 1UniRule annotation1

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Keywords - Molecular functioni

IsomeraseUniRule annotationSAAS annotationImported

Keywords - Biological processi

Carbohydrate metabolism, Pentose shuntUniRule annotationSAAS annotation, Xylose metabolismUniRule annotationSAAS annotation

Keywords - Ligandi

MagnesiumUniRule annotationSAAS annotation, Metal-bindingUniRule annotationSAAS annotation

Names & Taxonomyi

Protein namesi
Recommended name:
Xylose isomeraseUniRule annotationSAAS annotation (EC:5.3.1.5UniRule annotationSAAS annotation)
Gene namesi
Name:xylAUniRule annotation
Ordered Locus Names:RB2501_04540Imported
OrganismiRobiginitalea biformata (strain ATCC BAA-864 / HTCC2501 / KCTC 12146)Imported
Taxonomic identifieri313596 [NCBI]
Taxonomic lineageiBacteriaBacteroidetesFlavobacteriiaFlavobacterialesFlavobacteriaceaeRobiginitalea
Proteomesi
  • UP000009049 Componenti: Chromosome

Subcellular locationi

  • Cytoplasm UniRule annotationSAAS annotation

GO - Cellular componenti

Complete GO annotation...

Keywords - Cellular componenti

CytoplasmUniRule annotationSAAS annotation

Interactioni

Subunit structurei

Homotetramer.UniRule annotationSAAS annotation

Protein-protein interaction databases

STRINGi313596.RB2501_04540.

Structurei

3D structure databases

ProteinModelPortaliA4CGS8.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the xylose isomerase family.UniRule annotationSAAS annotation

Phylogenomic databases

eggNOGiENOG4105C93. Bacteria.
COG2115. LUCA.
HOGENOMiHOG000252293.
KOiK01805.
OMAiNQYILAD.
OrthoDBiPOG091H07LC.

Family and domain databases

Gene3Di3.20.20.150. 1 hit.
HAMAPiMF_00455. Xylose_isom_A. 1 hit.
InterProiIPR013022. Xyl_isomerase-like_TIM-brl.
IPR013452. Xylose_isom_bac.
IPR001998. Xylose_isomerase.
[Graphical view]
PRINTSiPR00688. XYLOSISMRASE.
SUPFAMiSSF51658. SSF51658. 1 hit.
TIGRFAMsiTIGR02630. xylose_isom_A. 1 hit.
PROSITEiPS51415. XYLOSE_ISOMERASE. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

A4CGS8-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MITTGDKEYF KNIGKIPFEG KESDNPLAFK YYDENQKVGD KTMKEHFRFA
60 70 80 90 100
VCYWHTFTGL GADPFGAPTQ QFPWLENSDP VQQAKDKMDA AFEFITKIGA
110 120 130 140 150
PYYCFHDYDL IAEGPTLAES ERRLDIITDY AREKMDASGV KLLWGTANCF
160 170 180 190 200
GNPRYMNGAA TNPDFKVLAA AGAQVKNALD ATIKLDGENY VFWGGREGYM
210 220 230 240 250
SLLNTDMKRE QDHMARFLHM ARDYARKQGF KGVFFIEPKP MEPTKHQYDF
260 270 280 290 300
DSATVLAFLS KYDLLDDFKL NIEVNHATLA QHTFEHELQV AADNGLLGSI
310 320 330 340 350
DANRGDYQNG WDTDQFPVDV YELTQAMLVI LEAGGFQGGG VNFDAKIRRN
360 370 380 390 400
STDLEDIFYA HIGGMDAFAR ALLAAHAVRT QSDFLKMRKD RYASFDSGKG
410 420 430 440
AEFEAGKLSL EDLHKFAGAN QEIPRTSGRQ ELYENIINQF I
Length:441
Mass (Da):49,844
Last modified:April 3, 2007 - v1
Checksum:i5F8537C7E025450B
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP001712 Genomic DNA. Translation: EAR16136.1.
RefSeqiWP_012813831.1. NC_013222.1.

Genome annotation databases

EnsemblBacteriaiEAR16136; EAR16136; RB2501_04540.
KEGGirbi:RB2501_04540.
PATRICi23331909. VBIRobBif55773_0239.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP001712 Genomic DNA. Translation: EAR16136.1.
RefSeqiWP_012813831.1. NC_013222.1.

3D structure databases

ProteinModelPortaliA4CGS8.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi313596.RB2501_04540.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiEAR16136; EAR16136; RB2501_04540.
KEGGirbi:RB2501_04540.
PATRICi23331909. VBIRobBif55773_0239.

Phylogenomic databases

eggNOGiENOG4105C93. Bacteria.
COG2115. LUCA.
HOGENOMiHOG000252293.
KOiK01805.
OMAiNQYILAD.
OrthoDBiPOG091H07LC.

Family and domain databases

Gene3Di3.20.20.150. 1 hit.
HAMAPiMF_00455. Xylose_isom_A. 1 hit.
InterProiIPR013022. Xyl_isomerase-like_TIM-brl.
IPR013452. Xylose_isom_bac.
IPR001998. Xylose_isomerase.
[Graphical view]
PRINTSiPR00688. XYLOSISMRASE.
SUPFAMiSSF51658. SSF51658. 1 hit.
TIGRFAMsiTIGR02630. xylose_isom_A. 1 hit.
PROSITEiPS51415. XYLOSE_ISOMERASE. 1 hit.
[Graphical view]
ProtoNetiSearch...

Entry informationi

Entry nameiA4CGS8_ROBBH
AccessioniPrimary (citable) accession number: A4CGS8
Entry historyi
Integrated into UniProtKB/TrEMBL: April 3, 2007
Last sequence update: April 3, 2007
Last modified: November 30, 2016
This is version 72 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.