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A4AU92

- A4AU92_MARSH

UniProt

A4AU92 - A4AU92_MARSH

Protein
Submitted name:

Bifunctional phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase

Gene

FB2170_08559

Organism
Maribacter sp. (strain HTCC2170 / KCCM 42371)
Status
Unreviewed - Annotation score: 1 out of 5- Protein predictedi
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    • History
      Entry version 50 (01 Oct 2014)
      Sequence version 1 (03 Apr 2007)
      Previous versions | rss
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    Functioni

    Catalytic activityi

    10-formyltetrahydrofolate + 5-amino-1-(5-phospho-D-ribosyl)imidazole-4-carboxamide = tetrahydrofolate + 5-formamido-1-(5-phospho-D-ribosyl)imidazole-4-carboxamide.SAAS annotation
    IMP + H2O = 5-formamido-1-(5-phospho-D-ribosyl)imidazole-4-carboxamide.SAAS annotation

    Pathwayi

    GO - Molecular functioni

    1. IMP cyclohydrolase activity Source: InterPro
    2. phosphoribosylaminoimidazolecarboxamide formyltransferase activity Source: InterPro

    GO - Biological processi

    1. 'de novo' IMP biosynthetic process Source: UniProtKB-UniPathway

    Keywords - Molecular functioni

    HydrolaseSAAS annotationImported, TransferaseSAAS annotationImported

    Keywords - Biological processi

    Purine biosynthesisSAAS annotation

    Enzyme and pathway databases

    BioCyciMSP313603:GH3X-1970-MONOMER.
    UniPathwayiUPA00074; UER00133.
    UPA00074; UER00135.

    Names & Taxonomyi

    Protein namesi
    Submitted name:
    Bifunctional phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolaseImported
    Gene namesi
    Ordered Locus Names:FB2170_08559Imported
    OrganismiMaribacter sp. (strain HTCC2170 / KCCM 42371)Imported
    Taxonomic identifieri313603 [NCBI]
    Taxonomic lineageiBacteriaBacteroidetesFlavobacteriiaFlavobacterialesFlavobacteriaceaeMaribacter
    ProteomesiUP000001602: Chromosome

    Structurei

    3D structure databases

    ProteinModelPortaliA4AU92.
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Phylogenomic databases

    HOGENOMiHOG000230373.
    KOiK00602.
    OMAiIRASSKN.

    Family and domain databases

    Gene3Di3.40.140.20. 2 hits.
    3.40.50.1380. 1 hit.
    InterProiIPR024051. AICAR_Tfase_dom.
    IPR002695. AICARFT_IMPCHas.
    IPR016193. Cytidine_deaminase-like.
    IPR011607. MGS-like_dom.
    [Graphical view]
    PANTHERiPTHR11692. PTHR11692. 1 hit.
    PfamiPF01808. AICARFT_IMPCHas. 1 hit.
    PF02142. MGS. 1 hit.
    [Graphical view]
    PIRSFiPIRSF000414. AICARFT_IMPCHas. 1 hit.
    SMARTiSM00798. AICARFT_IMPCHas. 1 hit.
    SM00851. MGS. 1 hit.
    [Graphical view]
    SUPFAMiSSF52335. SSF52335. 1 hit.
    SSF53927. SSF53927. 1 hit.

    Sequencei

    Sequence statusi: Complete.

    A4AU92-1 [UniParc]FASTAAdd to Basket

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    MSTKKATSAL ISVFHKDGLE PIVKKFNELG ITIYSTGGTE KFIKDLGIDV    50
    VPVEDVTSYP SILGGRVKTL HPKVFGGILN RQDHDGDVAQ LEEFEIPQLD 100
    IVIVDLYPFE KTMASGASEQ DIIEKIDIGG ISLIRAAAKN FKDVLCVSSM 150
    EDYAEVLELI TNGNGSTTIE DRKRFATKSF NVSSHYDSAI FNYFNANHEE 200
    AALKISETKG KVLRYGENPH QKGFFFGDFD AMFNKLHGKE LSYNNLLDVD 250
    AAVNLMNEFK NDDPTFAILK HNNACGLAMR DTLHQAYVDA LAGDPVSAFG 300
    GVLISNKEID KATAEEIHKL FCEVVIAPSY ADDALEILKG KKNRIILIQN 350
    DVELPHNQVR TCLNGVLLQD KDHKTDSLED LNTATNNSPS QREVEDLIFA 400
    SKLCKHTKSN TIVLAKNKQL CASGTGQTSR VDALNQAIHK AKSFNFDLQD 450
    AVMASDAFFP FPDCVEIAHK SGITSVIQPG GSIKDQLSID YCNENNIAMV 500
    MTGTRHFKH 509
    Length:509
    Mass (Da):56,113
    Last modified:April 3, 2007 - v1
    Checksum:i2992A50C4C2D78AA
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    CP002157 Genomic DNA. Translation: EAR00543.1.
    RefSeqiWP_013306368.1. NC_014472.1.
    YP_003862601.1. NC_014472.1.

    Genome annotation databases

    EnsemblBacteriaiEAR00543; EAR00543; FB2170_08559.
    GeneIDi9719324.
    KEGGifbc:FB2170_08559.
    PATRICi42333459. VBIFlaBac16383_1986.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    CP002157 Genomic DNA. Translation: EAR00543.1 .
    RefSeqi WP_013306368.1. NC_014472.1.
    YP_003862601.1. NC_014472.1.

    3D structure databases

    ProteinModelPortali A4AU92.
    ModBasei Search...
    MobiDBi Search...

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    EnsemblBacteriai EAR00543 ; EAR00543 ; FB2170_08559 .
    GeneIDi 9719324.
    KEGGi fbc:FB2170_08559.
    PATRICi 42333459. VBIFlaBac16383_1986.

    Phylogenomic databases

    HOGENOMi HOG000230373.
    KOi K00602.
    OMAi IRASSKN.

    Enzyme and pathway databases

    UniPathwayi UPA00074 ; UER00133 .
    UPA00074 ; UER00135 .
    BioCyci MSP313603:GH3X-1970-MONOMER.

    Family and domain databases

    Gene3Di 3.40.140.20. 2 hits.
    3.40.50.1380. 1 hit.
    InterProi IPR024051. AICAR_Tfase_dom.
    IPR002695. AICARFT_IMPCHas.
    IPR016193. Cytidine_deaminase-like.
    IPR011607. MGS-like_dom.
    [Graphical view ]
    PANTHERi PTHR11692. PTHR11692. 1 hit.
    Pfami PF01808. AICARFT_IMPCHas. 1 hit.
    PF02142. MGS. 1 hit.
    [Graphical view ]
    PIRSFi PIRSF000414. AICARFT_IMPCHas. 1 hit.
    SMARTi SM00798. AICARFT_IMPCHas. 1 hit.
    SM00851. MGS. 1 hit.
    [Graphical view ]
    SUPFAMi SSF52335. SSF52335. 1 hit.
    SSF53927. SSF53927. 1 hit.
    ProtoNeti Search...

    Publicationsi

    1. "Complete genome sequence of strain HTCC2170, a novel member of the genus Maribacter in the family Flavobacteriaceae."
      Oh H.M., Kang I., Yang S.J., Jang Y., Vergin K.L., Giovannoni S.J., Cho J.C.
      J. Bacteriol. 193:303-304(2011) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: HTCC2170 / KCCM 42371Imported.

    Entry informationi

    Entry nameiA4AU92_MARSH
    AccessioniPrimary (citable) accession number: A4AU92
    Entry historyi
    Integrated into UniProtKB/TrEMBL: April 3, 2007
    Last sequence update: April 3, 2007
    Last modified: October 1, 2014
    This is version 50 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiUnreviewed (UniProtKB/TrEMBL)

    Miscellaneousi

    Keywords - Technical termi

    Complete proteome, Multifunctional enzymeSAAS annotation, Reference proteomeImported

    External Data

    Dasty 3