A4AU92 (A4AU92_MARSH) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Submitted name:
Bifunctional phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase EMBL EAR00543.1

Gene names

Ordered Locus Names:

FB2170_08559 EMBL EAR00543.1

Organism

Maribacter sp. (strain HTCC2170 / KCCM 42371) [Complete proteome] [HAMAP]

Taxonomic identifier

313603 [NCBI]

Taxonomic lineage

cellular organisms › Bacteria › Bacteroidetes/Chlorobi group › Bacteroidetes › Flavobacteriia › Flavobacteriales › Flavobacteriaceae › Maribacter

Protein attributes

Sequence length	509 AA.
Sequence status	Complete.
Protein existence	Predicted

General annotation (Comments)

Catalytic activity	10-formyltetrahydrofolate + 5-amino-1-(5-phospho-D-ribosyl)imidazole-4-carboxamide = tetrahydrofolate + 5-formamido-1-(5-phospho-D-ribosyl)imidazole-4-carboxamide. SAAS SAAS024051 IMP + H2O = 5-formamido-1-(5-phospho-D-ribosyl)imidazole-4-carboxamide. SAAS SAAS024051
Pathway	Purine metabolism; IMP biosynthesis via de novo pathway; 5-formamido-1-(5-phospho-D-ribosyl)imidazole-4-carboxamide from 5-amino-1-(5-phospho-D-ribosyl)imidazole-4-carboxamide (10-formyl THF route): step 1/1. SAAS SAAS024051 Purine metabolism; IMP biosynthesis via de novo pathway; IMP from 5-formamido-1-(5-phospho-D-ribosyl)imidazole-4-carboxamide: step 1/1. SAAS SAAS024051

Ontologies

Keywords
Biological process	Purine biosynthesis SAAS SAAS024051
Molecular function	Hydrolase SAAS SAAS024051 EMBL EAR00543.1 Transferase SAAS SAAS024051 EMBL EAR00543.1
Technical term	Complete proteome Multifunctional enzyme SAAS SAAS024051
Gene Ontology (GO)
Biological_process	'de novo' IMP biosynthetic process Inferred from electronic annotation. Source: UniProtKB-UniPathway
Molecular_function	IMP cyclohydrolase activity Inferred from electronic annotation. Source: InterPro phosphoribosylaminoimidazolecarboxamide formyltransferase activity Inferred from electronic annotation. Source: InterPro
Complete GO annotation...

Sequences

	Sequence		Length	Mass (Da)
	A4AU92 [UniParc]. Last modified April 3, 2007. Version 1. Checksum: 2992A50C4C2D78AA	FASTA	509	56,113
	10 20 30 40 50 60 MSTKKATSAL ISVFHKDGLE PIVKKFNELG ITIYSTGGTE KFIKDLGIDV VPVEDVTSYP 70 80 90 100 110 120 SILGGRVKTL HPKVFGGILN RQDHDGDVAQ LEEFEIPQLD IVIVDLYPFE KTMASGASEQ 130 140 150 160 170 180 DIIEKIDIGG ISLIRAAAKN FKDVLCVSSM EDYAEVLELI TNGNGSTTIE DRKRFATKSF 190 200 210 220 230 240 NVSSHYDSAI FNYFNANHEE AALKISETKG KVLRYGENPH QKGFFFGDFD AMFNKLHGKE 250 260 270 280 290 300 LSYNNLLDVD AAVNLMNEFK NDDPTFAILK HNNACGLAMR DTLHQAYVDA LAGDPVSAFG 310 320 330 340 350 360 GVLISNKEID KATAEEIHKL FCEVVIAPSY ADDALEILKG KKNRIILIQN DVELPHNQVR 370 380 390 400 410 420 TCLNGVLLQD KDHKTDSLED LNTATNNSPS QREVEDLIFA SKLCKHTKSN TIVLAKNKQL 430 440 450 460 470 480 CASGTGQTSR VDALNQAIHK AKSFNFDLQD AVMASDAFFP FPDCVEIAHK SGITSVIQPG 490 500 GSIKDQLSID YCNENNIAMV MTGTRHFKH

References

[1]

"Complete genome sequence of strain HTCC2170, a novel member of the genus Maribacter in the family Flavobacteriaceae." Oh H.M., Kang I., Yang S.J., Jang Y., Vergin K.L., Giovannoni S.J., Cho J.C. J. Bacteriol. 193:303-304(2011) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: HTCC2170 / KCCM 42371.

Cross-references

Sequence databases
EMBL GenBank DDBJ	CP002157 Genomic DNA. Translation: EAR00543.1.
RefSeq	YP_003862601.1. NC_014472.1.
3D structure databases
ProteinModelPortal	A4AU92.
ModBase	Search...
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
EnsemblBacteria	EAR00543; EAR00543; FB2170_08559.
GeneID	9719324.
KEGG	fbc:FB2170_08559.
PATRIC	42333459. VBIFlaBac16383_1986.
Organism-specific databases
CMR	Search...
Phylogenomic databases
HOGENOM	HOG000230373.
KO	K00602.
ProtClustDB	PRK00881.
Enzyme and pathway databases
BioCyc	MSP313603:GH3X-1968-MONOMER.
UniPathway	UPA00074; UER00133. UPA00074; UER00135.
Family and domain databases
Gene3D	3.40.140.20. 2 hits. 3.40.50.1380. 1 hit.
InterPro	IPR024051. AICAR_Tfase_dom. IPR002695. AICARFT_IMPCHas. IPR016193. Cytidine_deaminase-like. IPR011607. MGS-like_dom. [Graphical view]
PANTHER	PTHR11692. PTHR11692. 1 hit.
Pfam	PF01808. AICARFT_IMPCHas. 1 hit. PF02142. MGS. 1 hit. [Graphical view]
PIRSF	PIRSF000414. AICARFT_IMPCHas. 1 hit.
SMART	SM00798. AICARFT_IMPCHas. 1 hit. SM00851. MGS. 1 hit. [Graphical view]
SUPFAM	SSF53927. Cytidine_deaminase-like. 1 hit. SSF52335. MGS-like_dom. 1 hit.
ProtoNet	Search...

Entry information

Entry name

A4AU92_MARSH

Accession

Primary (citable) accession number: A4AU92

Entry history

Integrated into UniProtKB/TrEMBL:	April 3, 2007
Last sequence update:	April 3, 2007
Last modified:	May 1, 2013
This is version 45 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)