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A4ATE1 (A4ATE1_MARSH) Unreviewed, UniProtKB/TrEMBL

Last modified February 19, 2014. Version 37. Feed History...

Clusters with 100%, 90%, 50% identity | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein namesRecommended name:
Kynurenine 3-monooxygenase HAMAP-Rule MF_01971

EC=1.14.13.9 HAMAP-Rule MF_01971
Alternative name(s):
Kynurenine 3-hydroxylase HAMAP-Rule MF_01971
Gene names
Name:kmo HAMAP-Rule MF_01971
Ordered Locus Names:FB2170_16541 EMBL EAR00711.1
OrganismMaribacter sp. (strain HTCC2170 / KCCM 42371) [Complete proteome] [HAMAP] EMBL EAR00711.1
Taxonomic identifier313603 [NCBI]
Taxonomic lineageBacteriaBacteroidetesFlavobacteriiaFlavobacterialesFlavobacteriaceaeMaribacter

Protein attributes

Sequence length447 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

Catalyzes the hydroxylation of L-kynurenine (L-Kyn) to form 3-hydroxy-L-kynurenine (L-3OHKyn). Required for synthesis of quinolinic acid By similarity. HAMAP-Rule MF_01971

Catalytic activity

L-kynurenine + NADPH + O2 = 3-hydroxy-L-kynurenine + NADP+ + H2O. HAMAP-Rule MF_01971

Cofactor

FAD By similarity. HAMAP-Rule MF_01971

Pathway

Cofactor biosynthesis; NAD(+) biosynthesis; quinolinate from L-kynurenine: step 1/3. HAMAP-Rule MF_01971

Sequence similarities

Belongs to the aromatic-ring hydroxylase family. KMO subfamily. HAMAP-Rule MF_01971

Sequences

Sequence LengthMass (Da)Tools
A4ATE1 [UniParc].

Last modified April 3, 2007. Version 1.
Checksum: C9FE092A7DF82B8C

FASTA44751,706
        10         20         30         40         50         60 
MSQTSKNIAI VGSGLVGSLL AIYLRKLGHA ITVFDRRPDI RTIEFSGRSI NLAMSNRGWR 

        70         80         90        100        110        120 
ALDEIGIEEE IKKIAIPLDK RAMHVVGKPM YFQHYGEEGE AIWSISRGVL NRKMIDLAEE 

       130        140        150        160        170        180 
AGVKFKFEEK VWDVDLPAAK LQTGETEKGE WKEYAYDLIF GCDGAFSRIR HKMQRRSRFD 

       190        200        210        220        230        240 
YSQDFIDVGY KELTIPANSD GSHKLDANSF HIWPRGRFMF IAMPNIDGSF TCTLFMPFEG 

       250        260        270        280        290        300 
DISFESIRTH EEARTFFRTH FPSVDQEIEN LAHDFFKNPT SAMVTMKCYP WTYWDKVALV 

       310        320        330        340        350        360 
GDSAHAIVPF YGQGMNAGFE DIFVLNKIIK EEGDNWEAIF QQYQKKRKPN ADAIAELSYR 

       370        380        390        400        410        420 
NFMEMSSKTA DPKFLMQKKI EKRFAQKYPD KWVPLYSRVT FSHRPYSEAL AIGNAQEKIM 

       430        440 
SQIMDFPDIE KKWDSDEIEQ EILNMLP 

« Hide

References

[1]"Complete genome sequence of strain HTCC2170, a novel member of the genus Maribacter in the family Flavobacteriaceae."
Oh H.M., Kang I., Yang S.J., Jang Y., Vergin K.L., Giovannoni S.J., Cho J.C.
J. Bacteriol. 193:303-304(2011) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: HTCC2170 / KCCM 42371.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
CP002157 Genomic DNA. Translation: EAR00711.1.
RefSeqYP_003860745.1. NC_014472.1.

3D structure databases

ProteinModelPortalA4ATE1.
ModBaseSearch...
MobiDBSearch...

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaEAR00711; EAR00711; FB2170_16541.
GeneID9717443.
KEGGfbc:FB2170_16541.
PATRIC42329605. VBIFlaBac16383_0082.

Organism-specific databases

CMRSearch...

Phylogenomic databases

HOGENOMHOG000251788.
KOK00486.
OMAQPMISVK.
ProtClustDBCLSK903475.

Enzyme and pathway databases

BioCycMSP313603:GH3X-87-MONOMER.
UniPathwayUPA00253; UER00328.

Family and domain databases

HAMAPMF_01971. Kynurenine_monooxygenase.
InterProIPR027545. Kynurenine_monooxygenase.
IPR002938. mOase_FAD-bd.
IPR003042. Rng_hydrolase-like.
[Graphical view]
PfamPF01494. FAD_binding_3. 1 hit.
[Graphical view]
PRINTSPR00420. RNGMNOXGNASE.
ProtoNetSearch...

Entry information

Entry nameA4ATE1_MARSH
AccessionPrimary (citable) accession number: A4ATE1
Entry history
Integrated into UniProtKB/TrEMBL: April 3, 2007
Last sequence update: April 3, 2007
Last modified: February 19, 2014
This is version 37 of the entry and version 1 of the sequence. [Complete history]
Entry statusUnreviewed (UniProtKB/TrEMBL)