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A4APG3

- A4APG3_MARSH

UniProt

A4APG3 - A4APG3_MARSH

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Protein
Thymidine kinase
Gene
tdk, FB2170_06340
Organism
Maribacter sp. (strain HTCC2170 / KCCM 42371)
Status
Unreviewed - Annotation score: 2 out of 5 - Protein inferred from homologyi

Functioni

Catalytic activityi

ATP + thymidine = ADP + thymidine 5'-phosphate.UniRule annotationSAAS annotations

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Active sitei94 – 941Proton acceptor By similarityUniRule annotation

Regions

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Nucleotide bindingi21 – 288ATP By similarityUniRule annotation
Nucleotide bindingi93 – 964ATP By similarityUniRule annotation

GO - Molecular functioni

  1. ATP binding Source: UniProtKB-HAMAP
  2. thymidine kinase activity Source: UniProtKB-HAMAP

GO - Biological processi

  1. DNA replication Source: UniProtKB-KW
Complete GO annotation...

Keywords - Molecular functioni

KinaseUniRule annotationSAAS annotationsImported, Transferase

Keywords - Biological processi

DNA synthesisUniRule annotationSAAS annotations

Keywords - Ligandi

ATP-bindingUniRule annotationSAAS annotations, Nucleotide-binding

Enzyme and pathway databases

BioCyciMSP313603:GH3X-1532-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
Thymidine kinaseUniRule annotation (EC:2.7.1.21UniRule annotation)
Gene namesi
Name:tdkUniRule annotation
Ordered Locus Names:FB2170_06340Imported
OrganismiMaribacter sp. (strain HTCC2170 / KCCM 42371)Imported
Taxonomic identifieri313603 [NCBI]
Taxonomic lineageiBacteriaBacteroidetesFlavobacteriiaFlavobacterialesFlavobacteriaceaeMaribacter
ProteomesiUP000001602: Chromosome

Subcellular locationi

Cytoplasm By similarity UniRule annotation

GO - Cellular componenti

  1. cytoplasm Source: UniProtKB-SubCell
Complete GO annotation...

Keywords - Cellular componenti

CytoplasmUniRule annotation

Interactioni

Subunit structurei

Homotetramer By similarity.UniRule annotation

Structurei

3D structure databases

ProteinModelPortaliA4APG3.

Family & Domainsi

Sequence similaritiesi

Phylogenomic databases

HOGENOMiHOG000076390.
KOiK00857.
OMAiDHISEST.

Family and domain databases

HAMAPiMF_00124. Thymidine_kinase.
InterProiIPR027417. P-loop_NTPase.
IPR001267. Thymidine_kinase.
IPR020634. Thymidine_kinase_subgr.
[Graphical view]
PANTHERiPTHR11441. PTHR11441. 1 hit.
PfamiPF00265. TK. 1 hit.
[Graphical view]
PIRSFiPIRSF035805. TK_cell. 1 hit.
SUPFAMiSSF52540. SSF52540. 1 hit.

Sequencei

Sequence statusi: Complete.

A4APG3-1 [UniParc]FASTAAdd to Basket

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MFLENTVNHK EQFGWIEVIC GSMFSGKTEE LIRRLKRAQF AKQKVEIFKP    50
MVDKRYHEEM VVSHDANEIR STPVPAAANI RILADTCDVI GIDEAQFFDD 100
EIVTVCNDLA NRGVRVIVAG LDMDFKGNPF GPMPALMATA EYVTKVHAVC 150
TRTGNLANYS FRKAHNDDLV LLGETGEYEP LSRAAYYKAM LKERVKEIDV 200
DVEEISKAKK DVNG 214
Length:214
Mass (Da):24,106
Last modified:April 3, 2007 - v1
Checksum:i6AD3BB7C42B54ED5
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
CP002157 Genomic DNA. Translation: EAR02885.1.
RefSeqiWP_013305933.1. NC_014472.1.
YP_003862165.1. NC_014472.1.

Genome annotation databases

EnsemblBacteriaiEAR02885; EAR02885; FB2170_06340.
GeneIDi9718888.
KEGGifbc:FB2170_06340.
PATRICi42332573. VBIFlaBac16383_1545.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
CP002157 Genomic DNA. Translation: EAR02885.1 .
RefSeqi WP_013305933.1. NC_014472.1.
YP_003862165.1. NC_014472.1.

3D structure databases

ProteinModelPortali A4APG3.
ModBasei Search...
MobiDBi Search...

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblBacteriai EAR02885 ; EAR02885 ; FB2170_06340 .
GeneIDi 9718888.
KEGGi fbc:FB2170_06340.
PATRICi 42332573. VBIFlaBac16383_1545.

Phylogenomic databases

HOGENOMi HOG000076390.
KOi K00857.
OMAi DHISEST.

Enzyme and pathway databases

BioCyci MSP313603:GH3X-1532-MONOMER.

Family and domain databases

HAMAPi MF_00124. Thymidine_kinase.
InterProi IPR027417. P-loop_NTPase.
IPR001267. Thymidine_kinase.
IPR020634. Thymidine_kinase_subgr.
[Graphical view ]
PANTHERi PTHR11441. PTHR11441. 1 hit.
Pfami PF00265. TK. 1 hit.
[Graphical view ]
PIRSFi PIRSF035805. TK_cell. 1 hit.
SUPFAMi SSF52540. SSF52540. 1 hit.
ProtoNeti Search...

Publicationsi

  1. "Complete genome sequence of strain HTCC2170, a novel member of the genus Maribacter in the family Flavobacteriaceae."
    Oh H.M., Kang I., Yang S.J., Jang Y., Vergin K.L., Giovannoni S.J., Cho J.C.
    J. Bacteriol. 193:303-304(2011) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: HTCC2170 / KCCM 42371.

Entry informationi

Entry nameiA4APG3_MARSH
AccessioniPrimary (citable) accession number: A4APG3
Entry historyi
Integrated into UniProtKB/TrEMBL: April 3, 2007
Last sequence update: April 3, 2007
Last modified: September 3, 2014
This is version 54 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome

External Data

Dasty 3

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