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A4AFX2

- A4AFX2_9ACTN

UniProt

A4AFX2 - A4AFX2_9ACTN

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Protein
Submitted name:

Mandelate racemase/muconate lactonizing enzyme

Gene

A20C1_08358

Organism
marine actinobacterium PHSC20C1
Status
Unreviewed - Annotation score: 1 out of 5- Experimental evidence at protein leveli

Functioni

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Metal bindingi215 – 2151MagnesiumImported
Metal bindingi241 – 2411MagnesiumImported
Metal bindingi268 – 2681MagnesiumImported

GO - Molecular functioni

  1. catalytic activity Source: InterPro
  2. metal ion binding Source: UniProtKB-KW
Complete GO annotation...

Keywords - Ligandi

MagnesiumImported, Metal-bindingSAAS annotationImported

Names & Taxonomyi

Protein namesi
Submitted name:
Mandelate racemase/muconate lactonizing enzymeImported
Gene namesi
ORF Names:A20C1_08358Imported
Organismimarine actinobacterium PHSC20C1Imported
Taxonomic identifieri312284 [NCBI]
Taxonomic lineageiBacteriaActinobacteria

Structurei

3D structure databases

Select the link destinations:
PDBei
RCSB PDBi
PDBji
Links Updated
EntryMethodResolution (Å)ChainPositionsPDBsum
3MSYX-ray2.50A/B/C/D/E/F20-388[»]
3NO1X-ray2.16A/B/C/D/E/F2-388[»]
4H83X-ray2.09A/B/C/D/E/F1-388[»]
ProteinModelPortaliA4AFX2.
ModBaseiSearch...
MobiDBiSearch...

Miscellaneous databases

EvolutionaryTraceiA4AFX2.

Family & Domainsi

Family and domain databases

Gene3Di3.20.20.120. 1 hit.
3.30.390.10. 1 hit.
InterProiIPR029065. Enolase_C-like.
IPR029017. Enolase_N_like.
IPR013342. Mandelate_racemase_C.
IPR013341. Mandelate_racemase_N_dom.
IPR001354. MR/MLE/MAL.
[Graphical view]
PANTHERiPTHR13794. PTHR13794. 1 hit.
PfamiPF01188. MR_MLE. 1 hit.
PF02746. MR_MLE_N. 1 hit.
[Graphical view]
SMARTiSM00922. MR_MLE. 1 hit.
[Graphical view]
SUPFAMiSSF51604. SSF51604. 1 hit.
SSF54826. SSF54826. 1 hit.

Sequencei

Sequence statusi: Complete.

A4AFX2-1 [UniParc]FASTAAdd to Basket

« Hide

        10         20         30         40         50
MHDQRVHAER DPLDPQAHGL TITRIETIPM VAPLAREFRG SHYHMTHRAT
60 70 80 90 100
IVTRVHTDAG IIGEAYTGDE HETMFDIDRI IHEELAPTLI GQDAMAIERL
110 120 130 140 150
WDSGYKVTFD ILRDRRLGLV ALAAVNTAIW DAVGKALKMP LWKLWGGYRN
160 170 180 190 200
ELPMIAIGGY YGEPLGSIAD EMHNYQELGL AGVKFKVGGL SAAEDAARIT
210 220 230 240 250
AAREAAGDDF IICIDANQGY KPAVAVDLSR RIADLNIRWF EEPVEWHNDK
260 270 280 290 300
RSMRDVRYQG SVPVCAGQTE FSASGCRDLM ETGAIDVCNF DSSWSGGPTA
310 320 330 340 350
WLRTAAIATS YDVQMGHHEE PQVSTHLLAS QPHGTIAECF HPDRDPFWWN
360 370 380
MITNRPKLNN GTLTLSDRPG LGWDLNWDYI DQYRVSKD
Length:388
Mass (Da):43,439
Last modified:April 3, 2007 - v1
Checksum:i32F2FB2DF83FCE2C
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AAOB01000002 Genomic DNA. Translation: EAR25878.1.
RefSeqiWP_009773310.1. NZ_CH672415.1.

Genome annotation databases

EnsemblBacteriaiEAR25878; EAR25878; A20C1_08358.
PATRICi25922165. VBIMarAct105506_0948.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AAOB01000002 Genomic DNA. Translation: EAR25878.1 .
RefSeqi WP_009773310.1. NZ_CH672415.1.

3D structure databases

Select the link destinations:
PDBei
RCSB PDBi
PDBji
Links Updated
Entry Method Resolution (Å) Chain Positions PDBsum
3MSY X-ray 2.50 A/B/C/D/E/F 20-388 [» ]
3NO1 X-ray 2.16 A/B/C/D/E/F 2-388 [» ]
4H83 X-ray 2.09 A/B/C/D/E/F 1-388 [» ]
ProteinModelPortali A4AFX2.
ModBasei Search...
MobiDBi Search...

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblBacteriai EAR25878 ; EAR25878 ; A20C1_08358 .
PATRICi 25922165. VBIMarAct105506_0948.

Miscellaneous databases

EvolutionaryTracei A4AFX2.

Family and domain databases

Gene3Di 3.20.20.120. 1 hit.
3.30.390.10. 1 hit.
InterProi IPR029065. Enolase_C-like.
IPR029017. Enolase_N_like.
IPR013342. Mandelate_racemase_C.
IPR013341. Mandelate_racemase_N_dom.
IPR001354. MR/MLE/MAL.
[Graphical view ]
PANTHERi PTHR13794. PTHR13794. 1 hit.
Pfami PF01188. MR_MLE. 1 hit.
PF02746. MR_MLE_N. 1 hit.
[Graphical view ]
SMARTi SM00922. MR_MLE. 1 hit.
[Graphical view ]
SUPFAMi SSF51604. SSF51604. 1 hit.
SSF54826. SSF54826. 1 hit.
ProtoNeti Search...

Publicationsi

  1. Murray A., Ferriera S., Johnson J., Kravitz S., Halpern A., Remington K., Beeson K., Tran B., Rogers Y.-H., Friedman R., Venter J.C.
    Submitted (FEB-2006) to the EMBL/GenBank/DDBJ databases
    Cited for: NUCLEOTIDE SEQUENCE.
    Strain: PHSC20C1Imported.
  2. "Crystal Structure of Mandelate racemase/muconate lactonizing enzyme from a Marine actinobacterium."
    Satyanarayana L., Burley S.K., Swaminathan S.
    Submitted (APR-2010) to the PDB data bank
    Cited for: X-RAY CRYSTALLOGRAPHY (2.50 ANGSTROMS) OF 20-388.
  3. "Crystal Structure of Mandelate racemase/muconate lactonizing enzyme from a Marine actinobacterium in complex with magnesium."
    Satyanarayana L., Burley S.K., Swaminathan S.
    Submitted (JUN-2010) to the PDB data bank
    Cited for: X-RAY CRYSTALLOGRAPHY (2.16 ANGSTROMS) OF 2-388 IN COMPLEX WITH MAGNESIUM.
  4. "Crystal structure of Mandelate racemase/muconate lactonizing enzyme."
    Kim J., Toro R., Bhosle R., Al Obaidi N.F., Morisco L.L., Wasserman S.R., Sojitra S., Washington E., Scott Glenn A., Chowdhury S., Evans B., Hammonds J., Stead M., Hillerich B., Love J., Seidel R.D., Imker H.J., Gerlt J.A., Almo S.C.
    Submitted (SEP-2012) to the PDB data bank
    Cited for: X-RAY CRYSTALLOGRAPHY (2.09 ANGSTROMS).

Entry informationi

Entry nameiA4AFX2_9ACTN
AccessioniPrimary (citable) accession number: A4AFX2
Entry historyi
Integrated into UniProtKB/TrEMBL: April 3, 2007
Last sequence update: April 3, 2007
Last modified: November 26, 2014
This is version 29 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Caution

The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.Imported

Keywords - Technical termi

3D-structureImported

External Data

Dasty 3