A3XZN9 (A3XZN9_9VIBR) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Recommended name:
Malonyl-CoA O-methyltransferase BioC HAMAP-Rule MF_00835
EC=2.1.1.197 HAMAP-Rule MF_00835

Alternative name(s):
Biotin synthesis protein BioC HAMAP-Rule MF_00835

Gene names

Name:	bioC HAMAP-Rule MF_00835
ORF Names:	MED222_12343 EMBL EAQ53313.1

Organism

Vibrio sp. MED222 EMBL EAQ53313.1

Taxonomic identifier

314290 [NCBI]

Taxonomic lineage

cellular organisms › Bacteria › Proteobacteria › Gammaproteobacteria › Vibrionales › Vibrionaceae › Vibrio

Protein attributes

Sequence length	267 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Function	Converts the free carboxyl group of a malonyl-thioester to its methyl ester by transfer of a methyl group from S-adenosyl-L-methionine (SAM). It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway By similarity. HAMAP-Rule MF_00835
Catalytic activity	S-adenosyl-L-methionine + malonyl-CoA = S-adenosyl-L-homocysteine + malonyl-CoA methyl ester. HAMAP-Rule MF_00835 SAAS SAAS011814
Pathway	Cofactor biosynthesis; biotin biosynthesis. HAMAP-Rule MF_00835 SAAS SAAS011814
Sequence similarities	Belongs to the methyltransferase superfamily. HAMAP-Rule MF_00835
Caution	The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

Ontologies

Keywords
Biological process	Biotin biosynthesis HAMAP-Rule MF_00835 SAAS SAAS011814
Ligand	S-adenosyl-L-methionine HAMAP-Rule MF_00835 SAAS SAAS011814
Molecular function	Methyltransferase HAMAP-Rule MF_00835 SAAS SAAS011814 Transferase
Gene Ontology (GO)
Biological_process	biotin biosynthetic process Inferred from electronic annotation. Source: HAMAP
Molecular_function	carboxyl-O-methyltransferase activity Inferred from electronic annotation. Source: HAMAP
Complete GO annotation...

Sequences

	Sequence		Length	Mass (Da)
	A3XZN9 [UniParc]. Last modified April 3, 2007. Version 1. Checksum: 6C03306641B3AA11	FASTA	267	29,625
	10 20 30 40 50 60 MSQEAVVHNY VSQDKSAIAE AFGKAAATYD KHAEFQRDVG HRLLDKLPSD LSGLKVLDLG 70 80 90 100 110 120 CGTGYFSEQL VKRGAAVVCA DLSNGMLDEA KQRCGVSVSS YQQADAEQLP FEDGHFDIVF 130 140 150 160 170 180 SSLALQWCDD LSSPLREMKR VTAVGGRVIF STLLDGSLFE LKKSWSKIDA HQHVNHFITI 190 200 210 220 230 240 NQVKIALAQS SCTAHQLDLP TITVWYDTAF ELMRDLKGIG ANHVSGRSQG LTSRRMLQLV 250 260 EREYREFKNH QGFLPATYQV CLGVIQL

References

[1]	Pinhassi J., Pedros-Alio C., Ferriera S., Johnson J., Kravitz S., Halpern A., Remington K., Beeson K., Tran B., Rogers Y.-H., Friedman R., Venter J.C. Submitted (JAN-2006) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE. Strain: MED222 EMBL EAQ53313.1.

Cross-references

Sequence databases
EMBL GenBank DDBJ	AAND01000016 Genomic DNA. Translation: EAQ53313.1.
3D structure databases
ProteinModelPortal	A3XZN9.
ModBase	Search...
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
EnsemblBacteria	EAQ53313; EAQ53313; MED222_12343.
PATRIC	28414399. VBIVibSp50596_3987.
Enzyme and pathway databases
UniPathway	UPA00078.
Family and domain databases
HAMAP	MF_00835. BioC.
InterPro	IPR011814. BioC. IPR013216. Methyltransf_11. [Graphical view]
Pfam	PF08241. Methyltransf_11. 1 hit. [Graphical view]
TIGRFAMs	TIGR02072. BioC. 1 hit.
ProtoNet	Search...

Entry information

Entry name

A3XZN9_9VIBR

Accession

Primary (citable) accession number: A3XZN9

Entry history

Integrated into UniProtKB/TrEMBL:	April 3, 2007
Last sequence update:	April 3, 2007
Last modified:	April 3, 2013
This is version 16 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)