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A3U7G2

- A3U7G2_CROAH

UniProt

A3U7G2 - A3U7G2_CROAH

Protein

Acetyltransferase component of pyruvate dehydrogenase complex

Gene

CA2559_05450

Organism
Croceibacter atlanticus (strain ATCC BAA-628 / HTCC2559 / KCTC 12090)
Status
Unreviewed - Annotation score: 2 out of 5- Protein inferred from homologyi
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    • History
      Entry version 44 (01 Oct 2014)
      Sequence version 1 (03 Apr 2007)
      Previous versions | rss
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    Functioni

    The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO2.UniRule annotation

    Catalytic activityi

    Acetyl-CoA + enzyme N(6)-(dihydrolipoyl)lysine = CoA + enzyme N(6)-(S-acetyldihydrolipoyl)lysine.

    Cofactori

    Binds 1 lipoyl cofactor covalently.UniRule annotation
    Binds 2 lipoyl cofactors covalently.UniRule annotation
    Binds 3 lipoyl cofactors covalently.UniRule annotation

    GO - Molecular functioni

    1. dihydrolipoyllysine-residue acetyltransferase activity Source: UniProtKB-EC

    GO - Biological processi

    1. pyruvate metabolic process Source: InterPro

    Keywords - Molecular functioni

    AcyltransferaseUniRule annotation, Transferase

    Keywords - Ligandi

    PyruvateImported

    Enzyme and pathway databases

    BioCyciCATL216432:GHTE-1108-MONOMER.

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    Acetyltransferase component of pyruvate dehydrogenase complexUniRule annotation (EC:2.3.1.12UniRule annotation)
    Gene namesi
    Ordered Locus Names:CA2559_05450Imported
    OrganismiCroceibacter atlanticus (strain ATCC BAA-628 / HTCC2559 / KCTC 12090)Imported
    Taxonomic identifieri216432 [NCBI]
    Taxonomic lineageiBacteriaBacteroidetesFlavobacteriiaFlavobacterialesFlavobacteriaceaeCroceibacter
    ProteomesiUP000002297: Chromosome

    Subcellular locationi

    GO - Cellular componenti

    1. pyruvate dehydrogenase complex Source: InterPro

    Structurei

    3D structure databases

    ProteinModelPortaliA3U7G2.
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Sequence similaritiesi

    Contains 2 lipoyl-binding domains.UniRule annotation

    Keywords - Domaini

    LipoylUniRule annotationSAAS annotation

    Phylogenomic databases

    HOGENOMiHOG000281566.
    KOiK00627.
    OMAiPISNIRK.

    Family and domain databases

    Gene3Di3.30.559.10. 1 hit.
    4.10.320.10. 1 hit.
    InterProiIPR003016. 2-oxoA_DH_lipoyl-BS.
    IPR001078. 2-oxoacid_DH_actylTfrase.
    IPR000089. Biotin_lipoyl.
    IPR023213. CAT-like_dom.
    IPR004167. E3-bd.
    IPR006257. LAT1.
    IPR011053. Single_hybrid_motif.
    [Graphical view]
    PfamiPF00198. 2-oxoacid_dh. 1 hit.
    PF00364. Biotin_lipoyl. 2 hits.
    PF02817. E3_binding. 1 hit.
    [Graphical view]
    SUPFAMiSSF47005. SSF47005. 1 hit.
    SSF51230. SSF51230. 2 hits.
    TIGRFAMsiTIGR01349. PDHac_trf_mito. 1 hit.
    PROSITEiPS50968. BIOTINYL_LIPOYL. 2 hits.
    PS00189. LIPOYL. 2 hits.
    [Graphical view]

    Sequencei

    Sequence statusi: Complete.

    A3U7G2-1 [UniParc]FASTAAdd to Basket

    « Hide

    MAEVINMPRL SDTMEEGVVA KWLKQKGDKV EEGDILAEIE TDKATMEFES    50
    FYEGVLLHIG VEEGETAPVD QLLAIIGEEG EDISDLLNGS SASGSKSDKE 100
    DKKSSESDNE ESNDEEKTDE KEESSSDDSG IPEGVEIITM PRLSDTMEEG 150
    TVATWLKQEG DTIEEGDILA EIETDKATME FESFYSGTLL KIGVAEGETA 200
    KVDKLLAIIG PEGTDVSGIS GDSPKASKAE TKSSKEEKDA KADTDKEETS 250
    SKSSTTSDGK RIFVSPLAKK MAEEKGIDLS EVNGSGDNGR IVKKDIENFK 300
    PSATSKKDTA QAKESQTNEA PTIQPYVPAG EESFEETKNS QMRKTIAKRL 350
    GESKFSAPHY YLTVEINMEH AMSSRSQINQ MPDVKVSYND MVIKAAAMAL 400
    RKHPQVNSQW DGDKTKVANH IHMGVAVAVD EGLLVPVLKF ADQMSLTQIG 450
    GNVKSLAGKA RNKKITPDEM SGSTFTVSNL GMFGITEFTS IINQPNSSIL 500
    SIGAIVEKPV VKNGEIVVGH TMKVTMANDH RTVDGATGAQ FLQTFKTYME 550
    NPVTMLA 557
    Length:557
    Mass (Da):60,325
    Last modified:April 3, 2007 - v1
    Checksum:i78C0A38C6A543D27
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    CP002046 Genomic DNA. Translation: EAP88179.1.
    RefSeqiYP_003715853.1. NC_014230.1.

    Genome annotation databases

    EnsemblBacteriaiEAP88179; EAP88179; CA2559_05450.
    GeneIDi9296583.
    KEGGicat:CA2559_05450.
    PATRICi38157766. VBICroAtl46233_1089.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    CP002046 Genomic DNA. Translation: EAP88179.1 .
    RefSeqi YP_003715853.1. NC_014230.1.

    3D structure databases

    ProteinModelPortali A3U7G2.
    ModBasei Search...
    MobiDBi Search...

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    EnsemblBacteriai EAP88179 ; EAP88179 ; CA2559_05450 .
    GeneIDi 9296583.
    KEGGi cat:CA2559_05450.
    PATRICi 38157766. VBICroAtl46233_1089.

    Phylogenomic databases

    HOGENOMi HOG000281566.
    KOi K00627.
    OMAi PISNIRK.

    Enzyme and pathway databases

    BioCyci CATL216432:GHTE-1108-MONOMER.

    Family and domain databases

    Gene3Di 3.30.559.10. 1 hit.
    4.10.320.10. 1 hit.
    InterProi IPR003016. 2-oxoA_DH_lipoyl-BS.
    IPR001078. 2-oxoacid_DH_actylTfrase.
    IPR000089. Biotin_lipoyl.
    IPR023213. CAT-like_dom.
    IPR004167. E3-bd.
    IPR006257. LAT1.
    IPR011053. Single_hybrid_motif.
    [Graphical view ]
    Pfami PF00198. 2-oxoacid_dh. 1 hit.
    PF00364. Biotin_lipoyl. 2 hits.
    PF02817. E3_binding. 1 hit.
    [Graphical view ]
    SUPFAMi SSF47005. SSF47005. 1 hit.
    SSF51230. SSF51230. 2 hits.
    TIGRFAMsi TIGR01349. PDHac_trf_mito. 1 hit.
    PROSITEi PS50968. BIOTINYL_LIPOYL. 2 hits.
    PS00189. LIPOYL. 2 hits.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. "The complete genome sequence of Croceibacter atlanticus HTCC2559T."
      Oh H.M., Kang I., Ferriera S., Giovannoni S.J., Cho J.C.
      J. Bacteriol. 192:4796-4797(2010) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: ATCC BAA-628 / HTCC2559 / KCTC 12090Imported.

    Entry informationi

    Entry nameiA3U7G2_CROAH
    AccessioniPrimary (citable) accession number: A3U7G2
    Entry historyi
    Integrated into UniProtKB/TrEMBL: April 3, 2007
    Last sequence update: April 3, 2007
    Last modified: October 1, 2014
    This is version 44 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiUnreviewed (UniProtKB/TrEMBL)

    Miscellaneousi

    Keywords - Technical termi

    Complete proteome, Reference proteomeImported

    External Data

    Dasty 3