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A3U7G2 (A3U7G2_CROAH) Unreviewed, UniProtKB/TrEMBL

Last modified July 9, 2014. Version 43. Feed History...

Clusters with 100%, 90%, 50% identity | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein namesRecommended name:
Acetyltransferase component of pyruvate dehydrogenase complex RuleBase RU361137

EC=2.3.1.12 RuleBase RU361137
Gene names
Ordered Locus Names:CA2559_05450 EMBL EAP88179.1
OrganismCroceibacter atlanticus (strain ATCC BAA-628 / HTCC2559 / KCTC 12090) [Complete proteome] [HAMAP] EMBL EAP88179.1
Taxonomic identifier216432 [NCBI]
Taxonomic lineageBacteriaBacteroidetesFlavobacteriiaFlavobacterialesFlavobacteriaceaeCroceibacter

Protein attributes

Sequence length557 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO2 By similarity. RuleBase RU361137

Catalytic activity

Acetyl-CoA + enzyme N(6)-(dihydrolipoyl)lysine = CoA + enzyme N(6)-(S-acetyldihydrolipoyl)lysine. RuleBase RU361137

Cofactor

Binds 1 lipoyl cofactor covalently By similarity. RuleBase RU361137

Binds 2 lipoyl cofactors covalently By similarity. RuleBase RU361137

Binds 3 lipoyl cofactors covalently By similarity. RuleBase RU361137

Sequence similarities

Belongs to the 2-oxoacid dehydrogenase family. RuleBase RU361137

Contains 2 lipoyl-binding domains. RuleBase RU361137

Sequences

Sequence LengthMass (Da)Tools
A3U7G2 [UniParc].

Last modified April 3, 2007. Version 1.
Checksum: 78C0A38C6A543D27

FASTA55760,325
        10         20         30         40         50         60 
MAEVINMPRL SDTMEEGVVA KWLKQKGDKV EEGDILAEIE TDKATMEFES FYEGVLLHIG 

        70         80         90        100        110        120 
VEEGETAPVD QLLAIIGEEG EDISDLLNGS SASGSKSDKE DKKSSESDNE ESNDEEKTDE 

       130        140        150        160        170        180 
KEESSSDDSG IPEGVEIITM PRLSDTMEEG TVATWLKQEG DTIEEGDILA EIETDKATME 

       190        200        210        220        230        240 
FESFYSGTLL KIGVAEGETA KVDKLLAIIG PEGTDVSGIS GDSPKASKAE TKSSKEEKDA 

       250        260        270        280        290        300 
KADTDKEETS SKSSTTSDGK RIFVSPLAKK MAEEKGIDLS EVNGSGDNGR IVKKDIENFK 

       310        320        330        340        350        360 
PSATSKKDTA QAKESQTNEA PTIQPYVPAG EESFEETKNS QMRKTIAKRL GESKFSAPHY 

       370        380        390        400        410        420 
YLTVEINMEH AMSSRSQINQ MPDVKVSYND MVIKAAAMAL RKHPQVNSQW DGDKTKVANH 

       430        440        450        460        470        480 
IHMGVAVAVD EGLLVPVLKF ADQMSLTQIG GNVKSLAGKA RNKKITPDEM SGSTFTVSNL 

       490        500        510        520        530        540 
GMFGITEFTS IINQPNSSIL SIGAIVEKPV VKNGEIVVGH TMKVTMANDH RTVDGATGAQ 

       550 
FLQTFKTYME NPVTMLA 

« Hide

References

[1]"Complete genome sequence of Croceibacter atlanticus HTCC2559T."
Oh H.M., Kang I., Ferriera S., Giovannoni S.J., Cho J.C.
J. Bacteriol. 192:4796-4797(2010) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: ATCC BAA-628 / HTCC2559 / KCTC 12090.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
CP002046 Genomic DNA. Translation: EAP88179.1.
RefSeqYP_003715853.1. NC_014230.1.

3D structure databases

ProteinModelPortalA3U7G2.
ModBaseSearch...
MobiDBSearch...

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaEAP88179; EAP88179; CA2559_05450.
GeneID9296583.
KEGGcat:CA2559_05450.
PATRIC38157766. VBICroAtl46233_1089.

Organism-specific databases

CMRSearch...

Phylogenomic databases

HOGENOMHOG000281566.
KOK00627.
OMAPISNIRK.

Enzyme and pathway databases

BioCycCATL216432:GHTE-1108-MONOMER.

Family and domain databases

Gene3D3.30.559.10. 1 hit.
4.10.320.10. 1 hit.
InterProIPR003016. 2-oxoA_DH_lipoyl-BS.
IPR001078. 2-oxoacid_DH_actylTfrase.
IPR000089. Biotin_lipoyl.
IPR023213. CAT-like_dom.
IPR004167. E3-bd.
IPR006257. LAT1.
IPR011053. Single_hybrid_motif.
[Graphical view]
PfamPF00198. 2-oxoacid_dh. 1 hit.
PF00364. Biotin_lipoyl. 2 hits.
PF02817. E3_binding. 1 hit.
[Graphical view]
SUPFAMSSF47005. SSF47005. 1 hit.
SSF51230. SSF51230. 2 hits.
TIGRFAMsTIGR01349. PDHac_trf_mito. 1 hit.
PROSITEPS50968. BIOTINYL_LIPOYL. 2 hits.
PS00189. LIPOYL. 2 hits.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameA3U7G2_CROAH
AccessionPrimary (citable) accession number: A3U7G2
Entry history
Integrated into UniProtKB/TrEMBL: April 3, 2007
Last sequence update: April 3, 2007
Last modified: July 9, 2014
This is version 43 of the entry and version 1 of the sequence. [Complete history]
Entry statusUnreviewed (UniProtKB/TrEMBL)