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A3U7G2

- A3U7G2_CROAH

UniProt

A3U7G2 - A3U7G2_CROAH

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Protein
Acetyltransferase component of pyruvate dehydrogenase complex
Gene
CA2559_05450
Organism
Croceibacter atlanticus (strain ATCC BAA-628 / HTCC2559 / KCTC 12090)
Status
Unreviewed - Annotation score: 2 out of 5 - Protein inferred from homologyi

Functioni

The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO2 By similarity.UniRule annotation

Catalytic activityi

Acetyl-CoA + enzyme N(6)-(dihydrolipoyl)lysine = CoA + enzyme N(6)-(S-acetyldihydrolipoyl)lysine.UniRule annotation

Cofactori

Binds 1 lipoyl cofactor covalently By similarity.UniRule annotation
Binds 2 lipoyl cofactors covalently By similarity.UniRule annotation
Binds 3 lipoyl cofactors covalently By similarity.UniRule annotation

GO - Molecular functioni

  1. dihydrolipoyllysine-residue acetyltransferase activity Source: InterPro

GO - Biological processi

  1. pyruvate metabolic process Source: InterPro
Complete GO annotation...

Keywords - Molecular functioni

AcyltransferaseUniRule annotation, Transferase

Keywords - Ligandi

PyruvateImported

Enzyme and pathway databases

BioCyciCATL216432:GHTE-1108-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
Acetyltransferase component of pyruvate dehydrogenase complexUniRule annotation (EC:2.3.1.12UniRule annotation)
Gene namesi
Ordered Locus Names:CA2559_05450Imported
OrganismiCroceibacter atlanticus (strain ATCC BAA-628 / HTCC2559 / KCTC 12090)Imported
Taxonomic identifieri216432 [NCBI]
Taxonomic lineageiBacteriaBacteroidetesFlavobacteriiaFlavobacterialesFlavobacteriaceaeCroceibacter
ProteomesiUP000002297: Chromosome

Subcellular locationi

GO - Cellular componenti

  1. pyruvate dehydrogenase complex Source: InterPro
Complete GO annotation...

Structurei

3D structure databases

ProteinModelPortaliA3U7G2.

Family & Domainsi

Sequence similaritiesi

Belongs to the 2-oxoacid dehydrogenase family.UniRule annotation
Contains 2 lipoyl-binding domains.UniRule annotation

Keywords - Domaini

LipoylUniRule annotationSAAS annotations

Phylogenomic databases

HOGENOMiHOG000281566.
KOiK00627.
OMAiPISNIRK.

Family and domain databases

Gene3Di3.30.559.10. 1 hit.
4.10.320.10. 1 hit.
InterProiIPR003016. 2-oxoA_DH_lipoyl-BS.
IPR001078. 2-oxoacid_DH_actylTfrase.
IPR000089. Biotin_lipoyl.
IPR023213. CAT-like_dom.
IPR004167. E3-bd.
IPR006257. LAT1.
IPR011053. Single_hybrid_motif.
[Graphical view]
PfamiPF00198. 2-oxoacid_dh. 1 hit.
PF00364. Biotin_lipoyl. 2 hits.
PF02817. E3_binding. 1 hit.
[Graphical view]
SUPFAMiSSF47005. SSF47005. 1 hit.
SSF51230. SSF51230. 2 hits.
TIGRFAMsiTIGR01349. PDHac_trf_mito. 1 hit.
PROSITEiPS50968. BIOTINYL_LIPOYL. 2 hits.
PS00189. LIPOYL. 2 hits.
[Graphical view]

Sequencei

Sequence statusi: Complete.

A3U7G2-1 [UniParc]FASTAAdd to Basket

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MAEVINMPRL SDTMEEGVVA KWLKQKGDKV EEGDILAEIE TDKATMEFES    50
FYEGVLLHIG VEEGETAPVD QLLAIIGEEG EDISDLLNGS SASGSKSDKE 100
DKKSSESDNE ESNDEEKTDE KEESSSDDSG IPEGVEIITM PRLSDTMEEG 150
TVATWLKQEG DTIEEGDILA EIETDKATME FESFYSGTLL KIGVAEGETA 200
KVDKLLAIIG PEGTDVSGIS GDSPKASKAE TKSSKEEKDA KADTDKEETS 250
SKSSTTSDGK RIFVSPLAKK MAEEKGIDLS EVNGSGDNGR IVKKDIENFK 300
PSATSKKDTA QAKESQTNEA PTIQPYVPAG EESFEETKNS QMRKTIAKRL 350
GESKFSAPHY YLTVEINMEH AMSSRSQINQ MPDVKVSYND MVIKAAAMAL 400
RKHPQVNSQW DGDKTKVANH IHMGVAVAVD EGLLVPVLKF ADQMSLTQIG 450
GNVKSLAGKA RNKKITPDEM SGSTFTVSNL GMFGITEFTS IINQPNSSIL 500
SIGAIVEKPV VKNGEIVVGH TMKVTMANDH RTVDGATGAQ FLQTFKTYME 550
NPVTMLA 557
Length:557
Mass (Da):60,325
Last modified:April 3, 2007 - v1
Checksum:i78C0A38C6A543D27
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
CP002046 Genomic DNA. Translation: EAP88179.1.
RefSeqiYP_003715853.1. NC_014230.1.

Genome annotation databases

EnsemblBacteriaiEAP88179; EAP88179; CA2559_05450.
GeneIDi9296583.
KEGGicat:CA2559_05450.
PATRICi38157766. VBICroAtl46233_1089.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
CP002046 Genomic DNA. Translation: EAP88179.1 .
RefSeqi YP_003715853.1. NC_014230.1.

3D structure databases

ProteinModelPortali A3U7G2.
ModBasei Search...
MobiDBi Search...

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblBacteriai EAP88179 ; EAP88179 ; CA2559_05450 .
GeneIDi 9296583.
KEGGi cat:CA2559_05450.
PATRICi 38157766. VBICroAtl46233_1089.

Phylogenomic databases

HOGENOMi HOG000281566.
KOi K00627.
OMAi PISNIRK.

Enzyme and pathway databases

BioCyci CATL216432:GHTE-1108-MONOMER.

Family and domain databases

Gene3Di 3.30.559.10. 1 hit.
4.10.320.10. 1 hit.
InterProi IPR003016. 2-oxoA_DH_lipoyl-BS.
IPR001078. 2-oxoacid_DH_actylTfrase.
IPR000089. Biotin_lipoyl.
IPR023213. CAT-like_dom.
IPR004167. E3-bd.
IPR006257. LAT1.
IPR011053. Single_hybrid_motif.
[Graphical view ]
Pfami PF00198. 2-oxoacid_dh. 1 hit.
PF00364. Biotin_lipoyl. 2 hits.
PF02817. E3_binding. 1 hit.
[Graphical view ]
SUPFAMi SSF47005. SSF47005. 1 hit.
SSF51230. SSF51230. 2 hits.
TIGRFAMsi TIGR01349. PDHac_trf_mito. 1 hit.
PROSITEi PS50968. BIOTINYL_LIPOYL. 2 hits.
PS00189. LIPOYL. 2 hits.
[Graphical view ]
ProtoNeti Search...

Publicationsi

  1. "Complete genome sequence of Croceibacter atlanticus HTCC2559T."
    Oh H.M., Kang I., Ferriera S., Giovannoni S.J., Cho J.C.
    J. Bacteriol. 192:4796-4797(2010) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: ATCC BAA-628 / HTCC2559 / KCTC 12090.

Entry informationi

Entry nameiA3U7G2_CROAH
AccessioniPrimary (citable) accession number: A3U7G2
Entry historyi
Integrated into UniProtKB/TrEMBL: April 3, 2007
Last sequence update: April 3, 2007
Last modified: July 9, 2014
This is version 43 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome

External Data

Dasty 3

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