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A3U5Q5

- A3U5Q5_CROAH

UniProt

A3U5Q5 - A3U5Q5_CROAH

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Protein
Thymidine kinase
Gene
tdk, CA2559_02415
Organism
Croceibacter atlanticus (strain ATCC BAA-628 / HTCC2559 / KCTC 12090)
Status
Unreviewed - Annotation score: 2 out of 5 - Protein inferred from homologyi

Functioni

Catalytic activityi

ATP + thymidine = ADP + thymidine 5'-phosphate.UniRule annotationSAAS annotations

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Active sitei94 – 941Proton acceptor By similarityUniRule annotation

Regions

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Nucleotide bindingi21 – 288ATP By similarityUniRule annotation
Nucleotide bindingi93 – 964ATP By similarityUniRule annotation

GO - Molecular functioni

  1. ATP binding Source: UniProtKB-HAMAP
  2. thymidine kinase activity Source: UniProtKB-HAMAP

GO - Biological processi

  1. DNA replication Source: UniProtKB-KW
Complete GO annotation...

Keywords - Molecular functioni

KinaseUniRule annotationSAAS annotationsImported, Transferase

Keywords - Biological processi

DNA synthesisUniRule annotationSAAS annotations

Keywords - Ligandi

ATP-bindingUniRule annotationSAAS annotations, Nucleotide-binding

Enzyme and pathway databases

BioCyciCATL216432:GHTE-493-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
Thymidine kinaseUniRule annotation (EC:2.7.1.21UniRule annotation)
Gene namesi
Name:tdkUniRule annotation
Ordered Locus Names:CA2559_02415Imported
OrganismiCroceibacter atlanticus (strain ATCC BAA-628 / HTCC2559 / KCTC 12090)Imported
Taxonomic identifieri216432 [NCBI]
Taxonomic lineageiBacteriaBacteroidetesFlavobacteriiaFlavobacterialesFlavobacteriaceaeCroceibacter
ProteomesiUP000002297: Chromosome

Subcellular locationi

Cytoplasm By similarity UniRule annotation

GO - Cellular componenti

  1. cytoplasm Source: UniProtKB-SubCell
Complete GO annotation...

Keywords - Cellular componenti

CytoplasmUniRule annotation

Interactioni

Subunit structurei

Homotetramer By similarity.UniRule annotation

Structurei

3D structure databases

ProteinModelPortaliA3U5Q5.

Family & Domainsi

Sequence similaritiesi

Phylogenomic databases

HOGENOMiHOG000076390.
KOiK00857.
OMAiQAICLSC.

Family and domain databases

HAMAPiMF_00124. Thymidine_kinase.
InterProiIPR027417. P-loop_NTPase.
IPR001267. Thymidine_kinase.
IPR020634. Thymidine_kinase_subgr.
[Graphical view]
PANTHERiPTHR11441. PTHR11441. 1 hit.
PfamiPF00265. TK. 1 hit.
[Graphical view]
PIRSFiPIRSF035805. TK_cell. 1 hit.
SUPFAMiSSF52540. SSF52540. 1 hit.

Sequencei

Sequence statusi: Complete.

A3U5Q5-1 [UniParc]FASTAAdd to Basket

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MFLENTVNHK EQFGWIEVIC GSMFSGKTEE LIRRLKRAKF ARQKVEIFKP    50
AIDVRYDEDM VVSHDANEIR STPVPAAANI RLLADGCDVV GIDEAQFFDD 100
EIVAVCNDLA NKGIRVIVAG LDMDFKGNPF GPMPNLMATA EYVTKVHAVC 150
TRTGNLAQYS FRKSENDKLV MLGETEEYEP LSRAAYFKAR LREKLKTMPV 200
KEAQELEAKK TPNN 214
Length:214
Mass (Da):24,152
Last modified:April 3, 2007 - v1
Checksum:i5409C47B2E6395D2
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
CP002046 Genomic DNA. Translation: EAP87572.1.
RefSeqiYP_003715249.1. NC_014230.1.

Genome annotation databases

EnsemblBacteriaiEAP87572; EAP87572; CA2559_02415.
GeneIDi9295968.
KEGGicat:CA2559_02415.
PATRICi38156522. VBICroAtl46233_0478.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
CP002046 Genomic DNA. Translation: EAP87572.1 .
RefSeqi YP_003715249.1. NC_014230.1.

3D structure databases

ProteinModelPortali A3U5Q5.
ModBasei Search...
MobiDBi Search...

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblBacteriai EAP87572 ; EAP87572 ; CA2559_02415 .
GeneIDi 9295968.
KEGGi cat:CA2559_02415.
PATRICi 38156522. VBICroAtl46233_0478.

Phylogenomic databases

HOGENOMi HOG000076390.
KOi K00857.
OMAi QAICLSC.

Enzyme and pathway databases

BioCyci CATL216432:GHTE-493-MONOMER.

Family and domain databases

HAMAPi MF_00124. Thymidine_kinase.
InterProi IPR027417. P-loop_NTPase.
IPR001267. Thymidine_kinase.
IPR020634. Thymidine_kinase_subgr.
[Graphical view ]
PANTHERi PTHR11441. PTHR11441. 1 hit.
Pfami PF00265. TK. 1 hit.
[Graphical view ]
PIRSFi PIRSF035805. TK_cell. 1 hit.
SUPFAMi SSF52540. SSF52540. 1 hit.
ProtoNeti Search...

Publicationsi

  1. "Complete genome sequence of Croceibacter atlanticus HTCC2559T."
    Oh H.M., Kang I., Ferriera S., Giovannoni S.J., Cho J.C.
    J. Bacteriol. 192:4796-4797(2010) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: ATCC BAA-628 / HTCC2559 / KCTC 12090.

Entry informationi

Entry nameiA3U5Q5_CROAH
AccessioniPrimary (citable) accession number: A3U5Q5
Entry historyi
Integrated into UniProtKB/TrEMBL: April 3, 2007
Last sequence update: April 3, 2007
Last modified: June 11, 2014
This is version 49 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome

External Data

Dasty 3

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