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Protein

Thymidine kinase

Gene

tdk

Organism
Croceibacter atlanticus (strain ATCC BAA-628 / HTCC2559 / KCTC 12090)
Status
Unreviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

Catalytic activityi

ATP + thymidine = ADP + thymidine 5'-phosphate.UniRule annotation

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Active sitei94 – 941Proton acceptorUniRule annotation

Regions

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Nucleotide bindingi21 – 288ATPUniRule annotation
Nucleotide bindingi93 – 964ATPUniRule annotation

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Keywords - Molecular functioni

KinaseUniRule annotation, Transferase

Keywords - Biological processi

DNA synthesisUniRule annotation

Keywords - Ligandi

ATP-bindingUniRule annotation, Nucleotide-binding

Enzyme and pathway databases

BioCyciCATL216432:GHTE-493-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
Thymidine kinaseUniRule annotation (EC:2.7.1.21UniRule annotation)
Gene namesi
Name:tdkUniRule annotation
Ordered Locus Names:CA2559_02415Imported
OrganismiCroceibacter atlanticus (strain ATCC BAA-628 / HTCC2559 / KCTC 12090)Imported
Taxonomic identifieri216432 [NCBI]
Taxonomic lineageiBacteriaBacteroidetesFlavobacteriiaFlavobacterialesFlavobacteriaceaeCroceibacter
ProteomesiUP000002297 Componenti: Chromosome

Subcellular locationi

  • Cytoplasm UniRule annotation

GO - Cellular componenti

Complete GO annotation...

Keywords - Cellular componenti

CytoplasmUniRule annotation

Interactioni

Subunit structurei

Homotetramer.UniRule annotation

Protein-protein interaction databases

STRINGi216432.CA2559_02415.

Structurei

3D structure databases

ProteinModelPortaliA3U5Q5.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the thymidine kinase family.UniRule annotation

Phylogenomic databases

HOGENOMiHOG000076390.
KOiK00857.
OMAiVTKVHAI.

Family and domain databases

HAMAPiMF_00124. Thymidine_kinase.
InterProiIPR027417. P-loop_NTPase.
IPR001267. Thymidine_kinase.
[Graphical view]
PANTHERiPTHR11441. PTHR11441. 1 hit.
PfamiPF00265. TK. 1 hit.
[Graphical view]
PIRSFiPIRSF035805. TK_cell. 1 hit.
SUPFAMiSSF52540. SSF52540. 1 hit.

Sequencei

Sequence statusi: Complete.

A3U5Q5-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MFLENTVNHK EQFGWIEVIC GSMFSGKTEE LIRRLKRAKF ARQKVEIFKP
60 70 80 90 100
AIDVRYDEDM VVSHDANEIR STPVPAAANI RLLADGCDVV GIDEAQFFDD
110 120 130 140 150
EIVAVCNDLA NKGIRVIVAG LDMDFKGNPF GPMPNLMATA EYVTKVHAVC
160 170 180 190 200
TRTGNLAQYS FRKSENDKLV MLGETEEYEP LSRAAYFKAR LREKLKTMPV
210
KEAQELEAKK TPNN
Length:214
Mass (Da):24,152
Last modified:April 3, 2007 - v1
Checksum:i5409C47B2E6395D2
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP002046 Genomic DNA. Translation: EAP87572.1.
RefSeqiWP_013186250.1. NC_014230.1.

Genome annotation databases

EnsemblBacteriaiEAP87572; EAP87572; CA2559_02415.
KEGGicat:CA2559_02415.
PATRICi38156522. VBICroAtl46233_0478.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP002046 Genomic DNA. Translation: EAP87572.1.
RefSeqiWP_013186250.1. NC_014230.1.

3D structure databases

ProteinModelPortaliA3U5Q5.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi216432.CA2559_02415.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiEAP87572; EAP87572; CA2559_02415.
KEGGicat:CA2559_02415.
PATRICi38156522. VBICroAtl46233_0478.

Phylogenomic databases

HOGENOMiHOG000076390.
KOiK00857.
OMAiVTKVHAI.

Enzyme and pathway databases

BioCyciCATL216432:GHTE-493-MONOMER.

Family and domain databases

HAMAPiMF_00124. Thymidine_kinase.
InterProiIPR027417. P-loop_NTPase.
IPR001267. Thymidine_kinase.
[Graphical view]
PANTHERiPTHR11441. PTHR11441. 1 hit.
PfamiPF00265. TK. 1 hit.
[Graphical view]
PIRSFiPIRSF035805. TK_cell. 1 hit.
SUPFAMiSSF52540. SSF52540. 1 hit.
ProtoNetiSearch...

Publicationsi

  1. "The complete genome sequence of Croceibacter atlanticus HTCC2559T."
    Oh H.M., Kang I., Ferriera S., Giovannoni S.J., Cho J.C.
    J. Bacteriol. 192:4796-4797(2010) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: ATCC BAA-628 / HTCC2559 / KCTC 12090Imported.

Entry informationi

Entry nameiA3U5Q5_CROAH
AccessioniPrimary (citable) accession number: A3U5Q5
Entry historyi
Integrated into UniProtKB/TrEMBL: April 3, 2007
Last sequence update: April 3, 2007
Last modified: July 22, 2015
This is version 58 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported

External Data

Dasty 3

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into Uniref entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.