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Protein

Thymidine kinase

Gene

tdk

Organism
Croceibacter atlanticus (strain ATCC BAA-628 / HTCC2559 / KCTC 12090)
Status
Unreviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

Catalytic activityi

ATP + thymidine = ADP + thymidine 5'-phosphate.UniRule annotation

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Active sitei94Proton acceptorUniRule annotation1

Regions

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Nucleotide bindingi21 – 28ATPUniRule annotation8
Nucleotide bindingi93 – 96ATPUniRule annotation4

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionKinaseUniRule annotationImported, Transferase
Biological processDNA synthesisUniRule annotation
LigandATP-bindingUniRule annotation, Nucleotide-binding

Names & Taxonomyi

Protein namesi
Recommended name:
Thymidine kinaseUniRule annotation (EC:2.7.1.21UniRule annotation)
Gene namesi
Name:tdkUniRule annotation
Ordered Locus Names:CA2559_02415Imported
OrganismiCroceibacter atlanticus (strain ATCC BAA-628 / HTCC2559 / KCTC 12090)Imported
Taxonomic identifieri216432 [NCBI]
Taxonomic lineageiBacteriaBacteroidetesFlavobacteriiaFlavobacterialesFlavobacteriaceaeCroceibacter
Proteomesi
  • UP000002297 Componenti: Chromosome

Subcellular locationi

  • Cytoplasm UniRule annotation

GO - Cellular componenti

Keywords - Cellular componenti

CytoplasmUniRule annotation

Interactioni

Subunit structurei

Homotetramer.UniRule annotation

Protein-protein interaction databases

STRINGi216432.CA2559_02415.

Structurei

3D structure databases

ProteinModelPortaliA3U5Q5.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the thymidine kinase family.UniRule annotation

Phylogenomic databases

eggNOGiENOG4107T8J. Bacteria.
COG1435. LUCA.
HOGENOMiHOG000076390.
KOiK00857.
OMAiKEQFGWI.
OrthoDBiPOG091H0659.

Family and domain databases

HAMAPiMF_00124. Thymidine_kinase. 1 hit.
InterProiView protein in InterPro
IPR027417. P-loop_NTPase.
IPR001267. Thymidine_kinase.
PANTHERiPTHR11441. PTHR11441. 1 hit.
PfamiView protein in Pfam
PF00265. TK. 1 hit.
PIRSFiPIRSF035805. TK_cell. 1 hit.
SUPFAMiSSF52540. SSF52540. 1 hit.

Sequencei

Sequence statusi: Complete.

A3U5Q5-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MFLENTVNHK EQFGWIEVIC GSMFSGKTEE LIRRLKRAKF ARQKVEIFKP
60 70 80 90 100
AIDVRYDEDM VVSHDANEIR STPVPAAANI RLLADGCDVV GIDEAQFFDD
110 120 130 140 150
EIVAVCNDLA NKGIRVIVAG LDMDFKGNPF GPMPNLMATA EYVTKVHAVC
160 170 180 190 200
TRTGNLAQYS FRKSENDKLV MLGETEEYEP LSRAAYFKAR LREKLKTMPV
210
KEAQELEAKK TPNN
Length:214
Mass (Da):24,152
Last modified:April 3, 2007 - v1
Checksum:i5409C47B2E6395D2
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP002046 Genomic DNA. Translation: EAP87572.1.
RefSeqiWP_013186250.1. NC_014230.1.

Genome annotation databases

EnsemblBacteriaiEAP87572; EAP87572; CA2559_02415.
KEGGicat:CA2559_02415.

Similar proteinsi

Entry informationi

Entry nameiA3U5Q5_CROAH
AccessioniPrimary (citable) accession number: A3U5Q5
Entry historyiIntegrated into UniProtKB/TrEMBL: April 3, 2007
Last sequence update: April 3, 2007
Last modified: September 27, 2017
This is version 68 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Caution

Lacks conserved residue(s) required for the propagation of feature annotation.UniRule annotation

Keywords - Technical termi

Complete proteome, Reference proteomeImported