A3RL32 (A3RL32_MOUSE) Unreviewed, UniProtKB/TrEMBL
Last modified
April 3, 2013.
Version 40.
History...
Names·Attributes·General annotation·Ontologies·Sequences·References·Cross-refs·Entry infoCustomize order
Names·Attributes·General annotation·Ontologies·Sequences·References·Cross-refs·Entry infoCustomize orderNames and origin
| Protein names | Recommended name: Interferon gamma PIRNR PIRNR001936 Short name=IFN-gamma PIRNR PIRNR001936 | ||
| Gene names |
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| Organism | Mus musculus (Mouse) EMBL ABN80441.1 | ||
| Taxonomic identifier | 10090 [NCBI] | ||
| Taxonomic lineage | Eukaryota › Metazoa › Chordata › Craniata › Vertebrata › Euteleostomi › Mammalia › Eutheria › Euarchontoglires › Glires › Rodentia › Sciurognathi › Muroidea › Muridae › Murinae › Mus › Mus![]() |
Protein attributes
| Sequence length | 155 AA. |
| Sequence status | Complete. |
| Protein existence | Evidence at transcript level |
General annotation (Comments)
| Function | Produced by lymphocytes activated by specific antigens or mitogens. IFN-gamma, in addition to having antiviral activity, has important immunoregulatory functions. It is a potent activator of macrophages, it has antiproliferative effects on transformed cells and it can potentiate the antiviral and antitumor effects of the type I interferons By similarity. PIRNR PIRNR001936 |
| Subunit structure | Homodimer By similarity. PIRNR PIRNR001936 |
| Subcellular location | Secreted By similarity PIRNR PIRNR001936. |
| Sequence similarities | Belongs to the type II (or gamma) interferon family. PIRNR PIRNR001936 |
Ontologies
Sequences
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References
| [1] | "Cloning and expression of a 468 bp cDNA fragment encoding 17.9 kDa gamma interferon of Mus musculus in eukaryotic bicistronic vector." Kadam M., Goswami P.P., Chakravarthy S., Tiwari V., Prasad N.S., Chandra Sekar S. Submitted (FEB-2007) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE. Strain: Swiss Albino EMBL ABN80441.1. |
| + | Additional computationally mapped references. |
Cross-references
Sequence databases | |
|---|---|
| EMBL GenBank DDBJ | EF423643 mRNA. Translation: ABN80441.1. |
| IPI | IPI00136892. |
| UniGene | Mm.240327. |
3D structure databases | |
| ProteinModelPortal | A3RL32. |
| ModBase | Search... |
Protocols and materials databases | |
| StructuralBiologyKnowledgebase | Search... |
Organism-specific databases | |
| MGI | MGI:107656. Ifng. |
Phylogenomic databases | |
| HOVERGEN | HBG056912. |
| InParanoid | A3RL32. |
Gene expression databases | |
| Genevestigator | A3RL32. |
Family and domain databases | |
| Gene3D | 1.20.1250.10. 1 hit. |
| InterPro | IPR009079. 4_helix_cytokine-like_core. IPR012351. 4_helix_cytokine_core. IPR002069. Interferon_gamma. [Graphical view] |
| PANTHER | PTHR11419. PTHR11419. 1 hit. |
| Pfam | PF00714. IFN-gamma. 1 hit. [Graphical view] |
| PIRSF | PIRSF001936. IFN-gamma. 1 hit. |
| ProDom | PD002435. Interferon_gamma. 1 hit. [Graphical view] [Entries sharing at least one domain] |
| SUPFAM | SSF47266. 4_helix_cytokine. 1 hit. |
| ProtoNet | Search... |
Other | |
| NextBio | 35544732. |
| SOURCE | Search... |
Entry information
| Entry name | A3RL32_MOUSE | ||||||||
| Accession | Primary (citable) accession number: A3RL32 | ||||||||
| Entry history |
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| Entry status | Unreviewed (UniProtKB/TrEMBL) | ||||||||

Clusters with
