Reviewed, UniProtKB/Swiss-Prot A3QJG1 (UBIC_SHELP)

Names and origin

Protein names

Recommended name:
    Probable chorismate--pyruvate lyase
      Short name=CL
      Short name=CPL
    EC=4.1.3.40

Gene names

Name:	ubiC
Ordered Locus Names:	Shew_3743

Organism

Shewanella loihica (strain ATCC BAA-1088 / PV-4) [Complete proteome] [HAMAP]

Taxonomic identifier

323850 [NCBI]

Taxonomic lineage

Bacteria › Proteobacteria › Gammaproteobacteria › Alteromonadales › Shewanellaceae › Shewanella

Protein attributes

Sequence length	188 AA.
Sequence status	Complete.
Sequence processing	The displayed sequence is not processed.
Protein existence	Inferred from homology.

General annotation (Comments)

Function	Removes the pyruvyl group from chorismate, with concomitant aromatization of the ring, to provide 4-hydroxybenzoate (4HB) for the ubiquinone pathway By similarity.
Catalytic activity	Chorismate = 4-hydroxybenzoate + pyruvate. HAMAP MF_01632
Pathway	Cofactor biosynthesis; ubiquinone biosynthesis. HAMAP MF_01632
Subcellular location	Cytoplasm By similarity.
Sequence similarities	Belongs to the ubiC family.

Ontologies

Keywords
Biological process	Ubiquinone biosynthesis
Cellular component	Cytoplasm
Ligand	Pyruvate
Molecular function	Lyase
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	pyruvate biosynthetic process Inferred from electronic annotation. Source: HAMAP ubiquinone biosynthetic process Inferred from electronic annotation. Source: HAMAP
Cellular component	cytoplasm Inferred from electronic annotation. Source: UniProtKB-SubCell
Molecular function	chorismate lyase activity Inferred from electronic annotation. Source: HAMAP
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 188	188	Probable chorismate--pyruvate lyase HAMAP MF_01632		PRO_0000292079
Sites
	Binding site	77	1	Substrate By similarity
	Binding site	115	1	Substrate; via amide nitrogen By similarity

Sequences

	Sequence		Length	Mass (Da)
	A3QJG1-1 [UniParc]. Last modified April 17, 2007. Version 1. Checksum: 2B591DFBA0192771	FASTA	188	21,151
	10 20 30 40 50 60 MSVTRLSFPY GESIQWHSPD QIPQLPPSPF REWLLASGSL TQKLKSHCNQ FEVKVLGEAM 70 80 90 100 110 120 LPPFPGELPH QGQAWIREVL LCLDGIPWVF ARTLVPGAMM DSAQDNFLSL GTRPLGELLF 130 140 150 160 170 180 TSGDFTPGKI EVGEFTACDS LAKLIDSLEQ ESHHPLWGRR RYFSHGDQQL IVSEIFLPKA RQLIDRLA

References

[1]

"Complete sequence of Shewanella loihica PV-4." Copeland A., Lucas S., Lapidus A., Barry K., Detter J.C., Glavina del Rio T., Hammon N., Israni S., Dalin E., Tice H., Pitluck S., Chain P., Malfatti S., Shin M., Vergez L., Schmutz J., Larimer F., Land M. , Hauser L., Kyrpides N., Mikhailova N., Romine M.F., Serres G., Fredrickson J., Tiedje J., Richardson P. Submitted (MAR-2007) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].

Cross-references

Sequence databases
EMBLGenBankDDBJ	CP000606 Genomic DNA. Translation: ABO25609.1.
RefSeq	YP_001095868.1.
3D structure databases
ModBase	Search...
Protein-protein interaction databases
STRING	A3QJG1.
Genome annotation databases
GeneID	4920918.
GenomeReviews	Gene locus Shew_3743 in contig CP000606_GR.
KEGG	slo:Shew_3743.
NMPDR	fig|323850.3.peg.1677.
Organism-specific databases
CMR	Search...
Phylogenomic databases
OMA	WGRRSRF.
Family and domain databases
HAMAP	MF_01632. [Tree]
InterPro	IPR007440. Chorismate--pyruvate_lyase. [Graphical view]
Pfam	PF04345. Chor_lyase. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

UBIC_SHELP

Accession

Primary (citable) accession number: A3QJG1

Entry history

Integrated into UniProtKB/Swiss-Prot:	June 26, 2007
Last sequence update:	April 17, 2007
Last modified:	November 3, 2009
This is version 18 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation project

HAMAP (High-quality Automated and Manual Annotation of microbial Proteomes)