SubmitCancel

Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.

A3QHI0

- GCSP_SHELP

UniProt

A3QHI0 - GCSP_SHELP

(max 400 entries)x

Your basket is currently empty.

Select item(s) and click on "Add to basket" to create your own collection here
(400 entries max)

Protein

Glycine dehydrogenase (decarboxylating)

Gene
gcvP, Shew_3062
Organism
Shewanella loihica (strain ATCC BAA-1088 / PV-4)
Status
Reviewed - Annotation score: 3 out of 5 - Protein inferred from homologyi

Functioni

The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO2 is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein By similarity.UniRule annotation

Catalytic activityi

Glycine + [glycine-cleavage complex H protein]-N(6)-lipoyl-L-lysine = [glycine-cleavage complex H protein]-S-aminomethyl-N(6)-dihydrolipoyl-L-lysine + CO2.UniRule annotation

Cofactori

Pyridoxal phosphate By similarity.UniRule annotation

GO - Molecular functioni

  1. glycine dehydrogenase (decarboxylating) activity Source: UniProtKB-EC
  2. pyridoxal phosphate binding Source: InterPro

GO - Biological processi

  1. glycine decarboxylation via glycine cleavage system Source: UniProtKB-HAMAP
Complete GO annotation...

Keywords - Molecular functioni

Oxidoreductase

Keywords - Ligandi

Pyridoxal phosphate

Enzyme and pathway databases

BioCyciSLOI323850:GHQJ-3167-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
Glycine dehydrogenase (decarboxylating) (EC:1.4.4.2)
Alternative name(s):
Glycine cleavage system P-protein
Glycine decarboxylase
Glycine dehydrogenase (aminomethyl-transferring)
Gene namesi
Name:gcvP
Ordered Locus Names:Shew_3062
OrganismiShewanella loihica (strain ATCC BAA-1088 / PV-4)
Taxonomic identifieri323850 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaAlteromonadalesShewanellaceaeShewanella
ProteomesiUP000001558: Chromosome

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 962962Glycine dehydrogenase (decarboxylating)UniRule annotationPRO_1000045610Add
BLAST

Amino acid modifications

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Modified residuei709 – 7091N6-(pyridoxal phosphate)lysine By similarity

Interactioni

Subunit structurei

The glycine cleavage system is composed of four proteins: P, T, L and H By similarity.

Protein-protein interaction databases

STRINGi323850.Shew_3062.

Structurei

3D structure databases

ProteinModelPortaliA3QHI0.

Family & Domainsi

Sequence similaritiesi

Belongs to the GcvP family.

Phylogenomic databases

eggNOGiCOG1003.
HOGENOMiHOG000239369.
KOiK00281.
OMAiFDSRPYS.
OrthoDBiEOG6HMXDX.

Family and domain databases

Gene3Di3.40.640.10. 2 hits.
HAMAPiMF_00711. GcvP.
InterProiIPR020580. GDC-P_N.
IPR020581. GDC_P.
IPR003437. GDC_P_homo.
IPR015424. PyrdxlP-dep_Trfase.
IPR015421. PyrdxlP-dep_Trfase_major_sub1.
[Graphical view]
PANTHERiPTHR11773. PTHR11773. 1 hit.
PfamiPF02347. GDC-P. 2 hits.
[Graphical view]
SUPFAMiSSF53383. SSF53383. 3 hits.
TIGRFAMsiTIGR00461. gcvP. 1 hit.

Sequencei

Sequence statusi: Complete.

A3QHI0-1 [UniParc]FASTAAdd to Basket

« Hide

MTTETLTQLE QHELFIRRHI GPDSADQQEM LNFVGAESLE DLTQQIVPES    50
IRLGRDLAVG SACGEAEGLA SIRKYADKNK VFKSYIGMGY YGTIVPSVIQ 100
RNVFENPGWY TAYTPYQPEI AQGRLEAILN FQQLSMDLTG LDLASASLLD 150
EATAAAEAMA LAKRVSKAKK ANIFFIADDV FPQTIDVVKT RAECFGFEIV 200
VGPASEAVNY ELFGALFQYT NHYGQITDFT ELFAALQEKK AVVTVAADIM 250
SLVSLKSPGS MGADVVFGSA QRFGVPMGFG GPHAAFFVTR DQHKRSLPGR 300
IIGVSQDTRG NRALRMAMQT REQHIRREKA NSNICTAQVL LANMASFYAV 350
FHGPQGLKII ADRIHRLADI FAAGLKAKGV ELVNNTWFDT VSFKVADSAA 400
AQARAIAGEV NLRIDSDGIL GVAMAETTTR EDVAQLFDIV LGEGHGLDVA 450
AIDADIIANG SNSIPAELVR QDAILEHPTF NRYHSETEMM RYIKRLENKD 500
LALNHSMISL GSCTMKLNAA TEMMPVSWPE FGNMHPFCPQ DQAQGYAELI 550
EELSNWLVDI TGYDAMCMQP NSGASGEYAG LLAIKKYHES RGEGHRNVCL 600
IPQSAHGTNP ASAQLAGMKI VVTACDKQGN VDMEDLKAKA AEVAENLSCI 650
MVTYPSTHGV YEETISEICE VIHQHGGQVY LDGANMNAQV GLTSPGSIGA 700
DVSHLNLHKT FAIPHGGGGP GMGPIGVKAH LAPFVAGHAV VKHGRESDNN 750
GAVSAAPYGS ASILPITWMY IKLLGYQGLR QSTQMALLNA NYVMKKLSAH 800
YPVLYTGRND RVAHECIIDL RPLKEASGVT EMDIAKRLND YGFHAPTMSF 850
PVAGTLMIEP TESESKAELD RFIEAMVAIR GEIAKVEAGE WPADNNPLHN 900
APHTMADIMD SEFDSRPYSR ETAVFPTAAV KANKFWPTVN RIDDVYGDRN 950
LMCSCAPIDD YK 962
Length:962
Mass (Da):104,745
Last modified:April 17, 2007 - v1
Checksum:i89C34F58A2602DB0
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
CP000606 Genomic DNA. Translation: ABO24928.1.
RefSeqiYP_001095187.1. NC_009092.1.

Genome annotation databases

EnsemblBacteriaiABO24928; ABO24928; Shew_3062.
GeneIDi4922662.
KEGGislo:Shew_3062.
PATRICi23518043. VBISheLoi132094_3061.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
CP000606 Genomic DNA. Translation: ABO24928.1 .
RefSeqi YP_001095187.1. NC_009092.1.

3D structure databases

ProteinModelPortali A3QHI0.
ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

STRINGi 323850.Shew_3062.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblBacteriai ABO24928 ; ABO24928 ; Shew_3062 .
GeneIDi 4922662.
KEGGi slo:Shew_3062.
PATRICi 23518043. VBISheLoi132094_3061.

Phylogenomic databases

eggNOGi COG1003.
HOGENOMi HOG000239369.
KOi K00281.
OMAi FDSRPYS.
OrthoDBi EOG6HMXDX.

Enzyme and pathway databases

BioCyci SLOI323850:GHQJ-3167-MONOMER.

Family and domain databases

Gene3Di 3.40.640.10. 2 hits.
HAMAPi MF_00711. GcvP.
InterProi IPR020580. GDC-P_N.
IPR020581. GDC_P.
IPR003437. GDC_P_homo.
IPR015424. PyrdxlP-dep_Trfase.
IPR015421. PyrdxlP-dep_Trfase_major_sub1.
[Graphical view ]
PANTHERi PTHR11773. PTHR11773. 1 hit.
Pfami PF02347. GDC-P. 2 hits.
[Graphical view ]
SUPFAMi SSF53383. SSF53383. 3 hits.
TIGRFAMsi TIGR00461. gcvP. 1 hit.
ProtoNeti Search...

Publicationsi

  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: ATCC BAA-1088 / PV-4.

Entry informationi

Entry nameiGCSP_SHELP
AccessioniPrimary (citable) accession number: A3QHI0
Entry historyi
Integrated into UniProtKB/Swiss-Prot: January 15, 2008
Last sequence update: April 17, 2007
Last modified: May 14, 2014
This is version 56 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3

Similar proteinsi