Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.

A3QH47

- SYL_SHELP

UniProt

A3QH47 - SYL_SHELP

(max 400 entries)x

Your basket is currently empty.

Select item(s) and click on "Add to basket" to create your own collection here
(400 entries max)

Protein

Leucine--tRNA ligase

Gene

leuS

Organism
Shewanella loihica (strain ATCC BAA-1088 / PV-4)
Status
Reviewed - Annotation score: 2 out of 5- Protein inferred from homologyi

Functioni

Catalytic activityi

ATP + L-leucine + tRNA(Leu) = AMP + diphosphate + L-leucyl-tRNA(Leu).UniRule annotation

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Binding sitei625 – 6251ATPUniRule annotation

GO - Molecular functioni

  1. aminoacyl-tRNA editing activity Source: InterPro
  2. ATP binding Source: UniProtKB-HAMAP
  3. leucine-tRNA ligase activity Source: UniProtKB-HAMAP

GO - Biological processi

  1. leucyl-tRNA aminoacylation Source: UniProtKB-HAMAP
Complete GO annotation...

Keywords - Molecular functioni

Aminoacyl-tRNA synthetase, Ligase

Keywords - Biological processi

Protein biosynthesis

Keywords - Ligandi

ATP-binding, Nucleotide-binding

Enzyme and pathway databases

BioCyciSLOI323850:GHQJ-3029-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
Leucine--tRNA ligaseUniRule annotation (EC:6.1.1.4UniRule annotation)
Alternative name(s):
Leucyl-tRNA synthetaseUniRule annotation
Short name:
LeuRSUniRule annotation
Gene namesi
Name:leuSUniRule annotation
Ordered Locus Names:Shew_2929
OrganismiShewanella loihica (strain ATCC BAA-1088 / PV-4)
Taxonomic identifieri323850 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaAlteromonadalesShewanellaceaeShewanella
ProteomesiUP000001558: Chromosome

Subcellular locationi

Cytoplasm UniRule annotation

GO - Cellular componenti

  1. cytoplasm Source: UniProtKB-HAMAP
Complete GO annotation...

Keywords - Cellular componenti

Cytoplasm

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 863863Leucine--tRNA ligasePRO_1000009424Add
BLAST

Proteomic databases

PRIDEiA3QH47.

Interactioni

Protein-protein interaction databases

STRINGi323850.Shew_2929.

Structurei

3D structure databases

ProteinModelPortaliA3QH47.
SMRiA3QH47. Positions 228-416.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Motif

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Motifi42 – 5211"HIGH" regionAdd
BLAST
Motifi622 – 6265"KMSKS" region

Sequence similaritiesi

Belongs to the class-I aminoacyl-tRNA synthetase family.UniRule annotation

Phylogenomic databases

eggNOGiCOG0495.
HOGENOMiHOG000200748.
KOiK01869.
OMAiHISHELW.
OrthoDBiEOG63Z74X.

Family and domain databases

Gene3Di1.10.730.10. 1 hit.
3.40.50.620. 3 hits.
3.90.740.10. 1 hit.
HAMAPiMF_00049_B. Leu_tRNA_synth_B.
InterProiIPR001412. aa-tRNA-synth_I_CS.
IPR002300. aa-tRNA-synth_Ia.
IPR002302. Leu-tRNA-ligase.
IPR025709. Leu_tRNA-synth_edit.
IPR014729. Rossmann-like_a/b/a_fold.
IPR009080. tRNAsynth_1a_anticodon-bd.
IPR013155. V/L/I-tRNA-synth_anticodon-bd.
IPR009008. Val/Leu/Ile-tRNA-synth_edit.
[Graphical view]
PANTHERiPTHR11946:SF7. PTHR11946:SF7. 1 hit.
PfamiPF08264. Anticodon_1. 1 hit.
PF00133. tRNA-synt_1. 3 hits.
PF13603. tRNA-synt_1_2. 1 hit.
[Graphical view]
PRINTSiPR00985. TRNASYNTHLEU.
SUPFAMiSSF47323. SSF47323. 1 hit.
SSF50677. SSF50677. 1 hit.
TIGRFAMsiTIGR00396. leuS_bact. 1 hit.
PROSITEiPS00178. AA_TRNA_LIGASE_I. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

A3QH47-1 [UniParc]FASTAAdd to Basket

« Hide

        10         20         30         40         50
MQEQYLPSEI EAKVQQHWQD TKTFEVTEDE SKEKFYCLSM FPYPSGRLHM
60 70 80 90 100
GHVRNYTIGD VVARYQRLQG KNVLQPIGWD SFGLPAENAA INNKTAPAPW
110 120 130 140 150
TYENIDYMKN QLKMLGFGYD WSREIATCTP EYYRWEQWFF TKLYEKGLVY
160 170 180 190 200
KKTASVNWCP NDETVLANEQ VQDGCCWRCD TQVVQKEIPQ WFIKITDYAE
210 220 230 240 250
ELLNDIDQLD EWPEQVKTMQ RNWIGRSEGI EMTFQVEGSD QSFDIYTTRP
260 270 280 290 300
DTVMGVTYVA IAAGHPLAQQ AAENNPVLAE FIEECKNADT TEAAMAAMEK
310 320 330 340 350
KGVDTGLKAI HPLTGKLVPI WAANFVLMNY GTGAVMSVPG HDQRDYEFAT
360 370 380 390 400
KYGLPIVGVI KPADGELDIS EEAYTEKGIL FNSGDSFPEL DGLDFQAAFD
410 420 430 440 450
AIDAKLSSEG KGKRQVNYRL RDWGVSRQRY WGAPIPMVTL ADGTVMPTPE
460 470 480 490 500
DQLPVILPED VVMDGIQSPI KADKEWAKTQ VNGQEAFRET DTFDTFMESS
510 520 530 540 550
WYYARYCSPK ADQMLDPAKA NYWLPVDQYI GGIEHACMHL LYFRFFHKLL
560 570 580 590 600
RDIGLVNSDE PAKRLLTQGM VLADAFYYTD DKGARVWVSP NDAKVTETDD
610 620 630 640 650
KGRIVKAVDS QGHELVYTGM SKMSKSKNNG IDPQEMVDKY GADTVRLFMM
660 670 680 690 700
FASPPELTLE WQESSVEGAH RFIKRLWKLA HDHVSQGPTV ALNVASLDSA
710 720 730 740 750
QKELRRELHK TIAKVGDDIE RRQMFNTAIA SVMELMNRLQ KAPMESEQDR
760 770 780 790 800
ALMQEALCAV VRLLYPIIPH TSFELWQALG HEETIENVLW PVVDESALVE
810 820 830 840 850
DSKLIIVQVN GKLRAKVTVA ADADKDTVEA AGMAEEGVIK HTEGKTVRKV
860
IYVPGKLLNI VAN
Length:863
Mass (Da):97,736
Last modified:April 17, 2007 - v1
Checksum:i8CD8A85373777D84
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP000606 Genomic DNA. Translation: ABO24795.1.
RefSeqiYP_001095054.1. NC_009092.1.

Genome annotation databases

EnsemblBacteriaiABO24795; ABO24795; Shew_2929.
GeneIDi4922131.
KEGGislo:Shew_2929.
PATRICi23517769. VBISheLoi132094_2929.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP000606 Genomic DNA. Translation: ABO24795.1 .
RefSeqi YP_001095054.1. NC_009092.1.

3D structure databases

ProteinModelPortali A3QH47.
SMRi A3QH47. Positions 228-416.
ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

STRINGi 323850.Shew_2929.

Proteomic databases

PRIDEi A3QH47.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblBacteriai ABO24795 ; ABO24795 ; Shew_2929 .
GeneIDi 4922131.
KEGGi slo:Shew_2929.
PATRICi 23517769. VBISheLoi132094_2929.

Phylogenomic databases

eggNOGi COG0495.
HOGENOMi HOG000200748.
KOi K01869.
OMAi HISHELW.
OrthoDBi EOG63Z74X.

Enzyme and pathway databases

BioCyci SLOI323850:GHQJ-3029-MONOMER.

Family and domain databases

Gene3Di 1.10.730.10. 1 hit.
3.40.50.620. 3 hits.
3.90.740.10. 1 hit.
HAMAPi MF_00049_B. Leu_tRNA_synth_B.
InterProi IPR001412. aa-tRNA-synth_I_CS.
IPR002300. aa-tRNA-synth_Ia.
IPR002302. Leu-tRNA-ligase.
IPR025709. Leu_tRNA-synth_edit.
IPR014729. Rossmann-like_a/b/a_fold.
IPR009080. tRNAsynth_1a_anticodon-bd.
IPR013155. V/L/I-tRNA-synth_anticodon-bd.
IPR009008. Val/Leu/Ile-tRNA-synth_edit.
[Graphical view ]
PANTHERi PTHR11946:SF7. PTHR11946:SF7. 1 hit.
Pfami PF08264. Anticodon_1. 1 hit.
PF00133. tRNA-synt_1. 3 hits.
PF13603. tRNA-synt_1_2. 1 hit.
[Graphical view ]
PRINTSi PR00985. TRNASYNTHLEU.
SUPFAMi SSF47323. SSF47323. 1 hit.
SSF50677. SSF50677. 1 hit.
TIGRFAMsi TIGR00396. leuS_bact. 1 hit.
PROSITEi PS00178. AA_TRNA_LIGASE_I. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: ATCC BAA-1088 / PV-4.

Entry informationi

Entry nameiSYL_SHELP
AccessioniPrimary (citable) accession number: A3QH47
Entry historyi
Integrated into UniProtKB/Swiss-Prot: January 15, 2008
Last sequence update: April 17, 2007
Last modified: October 29, 2014
This is version 62 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Aminoacyl-tRNA synthetases
    List of aminoacyl-tRNA synthetase entries
  2. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3