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Protein

Ribosomal RNA large subunit methyltransferase G

Gene

rlmG

Organism
Shewanella loihica (strain ATCC BAA-1088 / PV-4)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

Specifically methylates the guanine in position 1835 (m2G1835) of 23S rRNA.UniRule annotation

Catalytic activityi

S-adenosyl-L-methionine + guanine(1835) in 23S rRNA = S-adenosyl-L-homocysteine + N(2)-methylguanine(1835) in 23S rRNA.UniRule annotation

GO - Molecular functioni

Complete GO annotation...

Keywords - Molecular functioni

Methyltransferase, Transferase

Keywords - Biological processi

rRNA processing

Keywords - Ligandi

S-adenosyl-L-methionine

Names & Taxonomyi

Protein namesi
Recommended name:
Ribosomal RNA large subunit methyltransferase GUniRule annotation (EC:2.1.1.174UniRule annotation)
Alternative name(s):
23S rRNA m2G1835 methyltransferaseUniRule annotation
rRNA (guanine-N(2)-)-methyltransferase RlmGUniRule annotation
Gene namesi
Name:rlmGUniRule annotation
Ordered Locus Names:Shew_2886
OrganismiShewanella loihica (strain ATCC BAA-1088 / PV-4)
Taxonomic identifieri323850 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaAlteromonadalesShewanellaceaeShewanella
Proteomesi
  • UP000001558 Componenti: Chromosome

Subcellular locationi

  • Cytoplasm UniRule annotation

GO - Cellular componenti

Complete GO annotation...

Keywords - Cellular componenti

Cytoplasm

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00003665111 – 401Ribosomal RNA large subunit methyltransferase GAdd BLAST401

Interactioni

Protein-protein interaction databases

STRINGi323850.Shew_2886.

Structurei

3D structure databases

ProteinModelPortaliA3QH04.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the methyltransferase superfamily. RlmG family.UniRule annotation

Phylogenomic databases

eggNOGiENOG4105D8J. Bacteria.
COG2813. LUCA.
HOGENOMiHOG000246323.
KOiK00564.
OMAiFHQQQVV.
OrthoDBiPOG091H05RK.

Family and domain databases

Gene3Di3.40.50.150. 1 hit.
HAMAPiMF_01859. 23SrRNA_methyltr_G. 1 hit.
InterProiIPR002052. DNA_methylase_N6_adenine_CS.
IPR017237. rRNA_m2G-MeTrfase_RsmD.
IPR029063. SAM-dependent_MTases.
IPR007848. Small_mtfrase_dom.
[Graphical view]
PfamiPF05175. MTS. 1 hit.
[Graphical view]
PIRSFiPIRSF037565. RRNA_m2G_Mtase_RsmD_prd. 1 hit.
SUPFAMiSSF53335. SSF53335. 1 hit.

Sequencei

Sequence statusi: Complete.

A3QH04-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MTTQFSVADI ELSLSRYPAN QVSNLQAWDA ADEHLIKHLK EIEQKADNTA
60 70 80 90 100
VINDSFGALC AALTAQAADW PIWVETDAKT SQLGTLQNFN ANRLSDSNLT
110 120 130 140 150
WLNSRELPPQ GINLVLMKLP KNLNYFIHQL QRLSQSLAPN TPVYIGAKAK
160 170 180 190 200
SINKALLETI AKHLGPASAS LAWKKTRVIT CIADGKPRAL PSEVSWAVKE
210 220 230 240 250
FNLSISNLSN VFAANKLDIG ARIMLDNLPE GHFDTIVDLG CGNGILGLRA
260 270 280 290 300
KQCYPNAEVH FVDDSEMAIT SARQNWQANK LDNPEQAKPQ GHFHWDDCLT
310 320 330 340 350
HLGDEVKPDL VLCNPPFHQG EAITDHIAWQ MFLDAFHQLR PGGMLQVVGN
360 370 380 390 400
RHLGYHVKLK RIFKNCETAA SNGKFVILRA IKSAKEPVKP AKDVNEPDHQ

S
Length:401
Mass (Da):44,423
Last modified:April 17, 2007 - v1
Checksum:iAE89C041692DBA8D
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP000606 Genomic DNA. Translation: ABO24752.1.
RefSeqiWP_011866683.1. NC_009092.1.

Genome annotation databases

EnsemblBacteriaiABO24752; ABO24752; Shew_2886.
KEGGislo:Shew_2886.
PATRICi23517665. VBISheLoi132094_2885.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP000606 Genomic DNA. Translation: ABO24752.1.
RefSeqiWP_011866683.1. NC_009092.1.

3D structure databases

ProteinModelPortaliA3QH04.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi323850.Shew_2886.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiABO24752; ABO24752; Shew_2886.
KEGGislo:Shew_2886.
PATRICi23517665. VBISheLoi132094_2885.

Phylogenomic databases

eggNOGiENOG4105D8J. Bacteria.
COG2813. LUCA.
HOGENOMiHOG000246323.
KOiK00564.
OMAiFHQQQVV.
OrthoDBiPOG091H05RK.

Family and domain databases

Gene3Di3.40.50.150. 1 hit.
HAMAPiMF_01859. 23SrRNA_methyltr_G. 1 hit.
InterProiIPR002052. DNA_methylase_N6_adenine_CS.
IPR017237. rRNA_m2G-MeTrfase_RsmD.
IPR029063. SAM-dependent_MTases.
IPR007848. Small_mtfrase_dom.
[Graphical view]
PfamiPF05175. MTS. 1 hit.
[Graphical view]
PIRSFiPIRSF037565. RRNA_m2G_Mtase_RsmD_prd. 1 hit.
SUPFAMiSSF53335. SSF53335. 1 hit.
ProtoNetiSearch...

Entry informationi

Entry nameiRLMG_SHELP
AccessioniPrimary (citable) accession number: A3QH04
Entry historyi
Integrated into UniProtKB/Swiss-Prot: March 24, 2009
Last sequence update: April 17, 2007
Last modified: November 2, 2016
This is version 57 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.