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A3QGV7 (A3QGV7_SHELP) Unreviewed, UniProtKB/TrEMBL

Last modified May 1, 2013. Version 51. Feed History...

Clusters with 100%, 90%, 50% identity | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein namesRecommended name:
Carbamoyl-phosphate synthase small chain HAMAP-Rule MF_01209
EC=6.3.5.5 HAMAP-Rule MF_01209
Alternative name(s):
Carbamoyl-phosphate synthetase glutamine chain HAMAP-Rule MF_01209
Gene names
Name:carA HAMAP-Rule MF_01209
Ordered Locus Names:Shew_2839
OrganismShewanella loihica (strain ATCC BAA-1088 / PV-4) [Complete proteome] [HAMAP] EMBL ABO24705.1
Taxonomic identifier323850 [NCBI]
Taxonomic lineageBacteria › Proteobacteria › Gammaproteobacteria › Alteromonadales › Shewanellaceae › Shewanella ›

Protein attributes

Sequence length390 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Catalytic activity

2 ATP + L-glutamine + HCO3- + H2O = 2 ADP + phosphate + L-glutamate + carbamoyl phosphate. HAMAP-Rule MF_01209

Pathway

Amino-acid biosynthesis; L-arginine biosynthesis; carbamoyl phosphate from bicarbonate: step 1/1. HAMAP-Rule MF_01209

Pyrimidine metabolism; UMP biosynthesis via de novo pathway; (S)-dihydroorotate from bicarbonate: step 1/3. HAMAP-Rule MF_01209 SAAS SAAS006274

Subunit structure

Composed of two chains; the small (or glutamine) chain promotes the hydrolysis of glutamine to ammonia, which is used by the large (or ammonia) chain to synthesize carbamoyl phosphate By similarity. HAMAP-Rule MF_01209

Sequence similarities

Belongs to the CarA family. HAMAP-Rule MF_01209

Contains 1 glutamine amidotransferase type-1 domain. HAMAP-Rule MF_01209

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Regions

Domain201 – 388188Glutamine amidotransferase type-1 By similarity HAMAP-Rule MF_01209
Region1 – 197197CPSase By similarity HAMAP-Rule MF_01209

Sites

Active site2771Nucleophile By similarity HAMAP-Rule MF_01209
Active site3611 By similarity HAMAP-Rule MF_01209
Active site3631 By similarity HAMAP-Rule MF_01209

Sequences

Sequence LengthMass (Da)Tools
A3QGV7 [UniParc].

Last modified April 17, 2007. Version 1.
Checksum: CBB5C1B00A2DEC72

FASTA39042,031
        10         20         30         40         50         60 
MAWLFSEVAL TKSALLVLED GTVFSGTAIG ADGLAVGEVV FNTSMTGYQE ILTDPSYSRQ 

        70         80         90        100        110        120 
IVTLTYPHIG NTGTNSEDTE SEAVHACGLI IRDLPLLASN FRNEQSLSDY LKSNNVVGIA 

       130        140        150        160        170        180 
DIDTRKLTRI LREKGAQAGA ILVGDMDEAK ALAAAKAFPG LKGMDLAKEV TTQKQYQWRS 

       190        200        210        220        230        240 
GSWRLVGGLP SDTPESELKY KVVAYDYGVK RNILRMLVDR GCDVTVVPAQ TPAAEVLAMN 

       250        260        270        280        290        300 
PDGIFLSNGP GDPEPCDYAI EAIQAFLKTD IPLFGICLGH QLLALASGAK TLKMKFGHHG 

       310        320        330        340        350        360 
ANHPVSNLEK GNVMITSQNH GFAADETSLP ANVKVTHKSL FDGSLQGIHL TDKPAFSFQG 

       370        380        390 
HPEASPGPHD AAPLFDHFIE LIEEYRHNAK

« Hide

References

[1]"Complete sequence of Shewanella loihica PV-4."
US DOE Joint Genome Institute
Copeland A., Lucas S., Lapidus A., Barry K., Detter J.C., Glavina del Rio T., Hammon N., Israni S., Dalin E., Tice H., Pitluck S., Chain P., Malfatti S., Shin M., Vergez L., Schmutz J., Larimer F., Land M. expand/collapse author list , Hauser L., Kyrpides N., Mikhailova N., Romine M.F., Serres G., Fredrickson J., Tiedje J., Richardson P.
Submitted (MAR-2007) to the EMBL/GenBank/DDBJ databases
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: ATCC BAA-1088 / PV-4.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ		CP000606 Genomic DNA. Translation: ABO24705.1.
RefSeqYP_001094964.1. NC_009092.1.

3D structure databases

ProteinModelPortalA3QGV7.
SMRA3QGV7. Positions 12-389.
ModBaseSearch...

Protein-protein interaction databases

STRING323850.Shew_2839.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaABO24705; ABO24705; Shew_2839.
GeneID4922346.
KEGGslo:Shew_2839.
PATRIC23517571. VBISheLoi132094_2838.

Organism-specific databases

CMRSearch...

Phylogenomic databases

eggNOGCOG0505.
HOGENOMHOG000038087.
KOK01956.
OMARDSHYLF.
ProtClustDBPRK12564.

Enzyme and pathway databases

BioCycSLOI323850:GHQJ-2963-MONOMER.
UniPathwayUPA00068; UER00171.
UPA00070; UER00115.

Family and domain databases

Gene3D3.50.30.20. 1 hit.
HAMAPMF_01209. CPSase_S_chain.
InterProIPR006274. CarbamoylP_synth_ssu.
IPR002474. CarbamoylP_synth_ssu_N.
IPR017926. GATASE_1.
[Graphical view]
PfamPF00988. CPSase_sm_chain. 1 hit.
PF00117. GATase. 1 hit.
[Graphical view]
SMARTSM01097. CPSase_sm_chain. 1 hit.
[Graphical view]
SUPFAMSSF52021. CP_synthsmall. 1 hit.
TIGRFAMsTIGR01368. CPSaseIIsmall. 1 hit.
PROSITEPS51273. GATASE_TYPE_1. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameA3QGV7_SHELP
AccessionPrimary (citable) accession number: A3QGV7
Entry history
Integrated into UniProtKB/TrEMBL: April 17, 2007
Last sequence update: April 17, 2007
Last modified: May 1, 2013
This is version 51 of the entry and version 1 of the sequence. [Complete history]
Entry statusUnreviewed (UniProtKB/TrEMBL)
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info