A3QGV0 (GLMM_SHELP) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
Phosphoglucosamine mutase
EC=5.4.2.10

Gene names

Name:	glmM
Ordered Locus Names:	Shew_2832

Organism

Shewanella loihica (strain ATCC BAA-1088 / PV-4) [Complete proteome] [HAMAP]

Taxonomic identifier

323850 [NCBI]

Taxonomic lineage

cellular organisms › Bacteria › Proteobacteria › Gammaproteobacteria › Alteromonadales › Shewanellaceae › Shewanella › Shewanella loihica

Protein attributes

Sequence length	443 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Function	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate By similarity. HAMAP-Rule MF_01554
Catalytic activity	Alpha-D-glucosamine 1-phosphate = D-glucosamine 6-phosphate. HAMAP-Rule MF_01554
Cofactor	Binds 1 magnesium ion per subunit By similarity. HAMAP-Rule MF_01554
Post-translational modification	Activated by phosphorylation By similarity. HAMAP-Rule MF_01554
Sequence similarities	Belongs to the phosphohexose mutase family.

Ontologies

Keywords
Ligand	Magnesium Metal-binding
Molecular function	Isomerase
PTM	Phosphoprotein
Technical term	Complete proteome
Gene Ontology (GO)
Biological_process	carbohydrate metabolic process Inferred from electronic annotation. Source: InterPro
Molecular_function	magnesium ion binding Inferred from electronic annotation. Source: HAMAP phosphoglucosamine mutase activity Inferred from electronic annotation. Source: HAMAP
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 443	443	Phosphoglucosamine mutase HAMAP-Rule MF_01554		PRO_0000305674
Sites
	Active site	100	1	Phosphoserine intermediate By similarity
	Metal binding	100	1	Magnesium; via phosphate group By similarity
	Metal binding	239	1	Magnesium By similarity
	Metal binding	241	1	Magnesium By similarity
	Metal binding	243	1	Magnesium By similarity
Amino acid modifications
	Modified residue	100	1	Phosphoserine By similarity

Sequences

	Sequence		Length	Mass (Da)
	A3QGV0 [UniParc]. Last modified April 17, 2007. Version 1. Checksum: C8A1F5A8D8B5141E	FASTA	443	47,703
	10 20 30 40 50 60 MRKFFGTDGI RGKVGAGKMT PELALKLGWA AGRVLSRTGT KKVIIGKDTR ISGYLFESAM 70 80 90 100 110 120 EAGLSAAGLN VMLMGPMPTP AVAYLTRTFR AEAGVVISAS HNPYYDNGIK FFSTDGSKLD 130 140 150 160 170 180 DEVELEIERE LEKPLECVES HLLGKVSRIE DAAGRYIEYC KGNFPAEHTL NGLKIVVDCA 190 200 210 220 230 240 HGATYHIAPS VFRELGAEVI TIGDKPDGIN INHEVGATSM GKIRETVIAE KADLGIALDG 250 260 270 280 290 300 DGDRIMMVNR HGKVIDGDEI LYILACDAQD RGVLKGGVVG TLMSNLGLDL ALKARDIPFA 310 320 330 340 350 360 RSKVGDRYVM ELLKEKDWRI GGENSGHILN LDHGTTGDGI VAGILVLAAM CRKQATLEEL 370 380 390 400 410 420 TEGIKMLPQV LVNVRFEGTH NPLEADSVLS AQAEVEAKLG ERGRVLLRKS GTEPLIRVMV 430 440 EGDVASDVKA HANYIAEAIK ALV

References

[1]

"Complete sequence of Shewanella loihica PV-4." US DOE Joint Genome Institute Copeland A., Lucas S., Lapidus A., Barry K., Detter J.C., Glavina del Rio T., Hammon N., Israni S., Dalin E., Tice H., Pitluck S., Chain P., Malfatti S., Shin M., Vergez L., Schmutz J., Larimer F., Land M. , Hauser L., Kyrpides N., Mikhailova N., Romine M.F., Serres G., Fredrickson J., Tiedje J., Richardson P. Submitted (MAR-2007) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: ATCC BAA-1088 / PV-4.

Cross-references

Sequence databases
EMBL GenBank DDBJ	CP000606 Genomic DNA. Translation: ABO24698.1.
RefSeq	YP_001094957.1. NC_009092.1.
3D structure databases
ProteinModelPortal	A3QGV0.
ModBase	Search...
Protein-protein interaction databases
STRING	323850.Shew_2832.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
EnsemblBacteria	ABO24698; ABO24698; Shew_2832.
GeneID	4922339.
KEGG	slo:Shew_2832.
PATRIC	23517557. VBISheLoi132094_2831.
Organism-specific databases
CMR	Search...
Phylogenomic databases
eggNOG	COG1109.
HOGENOM	HOG000268678.
KO	K03431.
OMA	TLMSNMS.
ProtClustDB	PRK10887.
Enzyme and pathway databases
BioCyc	SLOI323850:GHQJ-2924-MONOMER.
Family and domain databases
Gene3D	3.40.120.10. 3 hits.
HAMAP	MF_01554_B. GlmM_B.
InterPro	IPR005844. A-D-PHexomutase_a/b/a-I. IPR016055. A-D-PHexomutase_a/b/a-I/II/III. IPR005845. A-D-PHexomutase_a/b/a-II. IPR005846. A-D-PHexomutase_a/b/a-III. IPR005843. A-D-PHexomutase_C. IPR016066. A-D-PHexomutase_CS. IPR005841. Alpha-D-phosphohexomutase_SF. IPR006352. GlmM. [Graphical view]
Pfam	PF02878. PGM_PMM_I. 1 hit. PF02879. PGM_PMM_II. 1 hit. PF02880. PGM_PMM_III. 1 hit. PF00408. PGM_PMM_IV. 1 hit. [Graphical view]
PRINTS	PR00509. PGMPMM.
SUPFAM	SSF53738. A-D-PHexomutase_a/b/a-I/II/III. 3 hits.
TIGRFAMs	TIGR01455. glmM. 1 hit.
PROSITE	PS00710. PGM_PMM. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

GLMM_SHELP

Accession

Primary (citable) accession number: A3QGV0

Entry history

Integrated into UniProtKB/Swiss-Prot:	October 2, 2007
Last sequence update:	April 17, 2007
Last modified:	May 29, 2013
This is version 45 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Prokaryotic Protein Annotation Program