A3QF29 (A3QF29_SHELP) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Recommended name:
Phosphoribosylaminoimidazole-succinocarboxamide synthase HAMAP MF_00137
EC=6.3.2.6 HAMAP MF_00137

Alternative name(s):
SAICAR synthetase HAMAP MF_00137

Gene names

Name:	purC HAMAP MF_00137
Ordered Locus Names:	Shew_2211

Organism

Shewanella loihica (strain ATCC BAA-1088 / PV-4) [Complete proteome] [HAMAP] EMBL ABO24077.1

Taxonomic identifier

323850 [NCBI]

Taxonomic lineage

Bacteria › Proteobacteria › Gammaproteobacteria › Alteromonadales › Shewanellaceae › Shewanella

Protein attributes

Sequence length	368 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Catalytic activity	ATP + 5-amino-1-(5-phospho-D-ribosyl)imidazole-4-carboxylate + L-aspartate = ADP + phosphate + (S)-2-(5-amino-1-(5-phospho-D-ribosyl)imidazole-4-carboxamido)succinate. HAMAP MF_00137
Pathway	Purine metabolism; IMP biosynthesis via de novo pathway; 5-amino-1-(5-phospho-D-ribosyl)imidazole-4-carboxamide from 5-amino-1-(5-phospho-D-ribosyl)imidazole-4-carboxylate: step 1/2. HAMAP MF_00137
Sequence similarities	Belongs to the SAICAR synthetase family. HAMAP MF_00137

Ontologies

Keywords
Biological process	Purine biosynthesis HAMAP MF_00137
Ligand	ATP-binding HAMAP MF_00137 Nucleotide-binding
Molecular function	Ligase HAMAP MF_00137 EMBL ABO24077.1
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	purine nucleotide biosynthetic process Inferred from electronic annotation. Source: HAMAP
Molecular function	ATP binding Inferred from electronic annotation. Source: UniProtKB-KW phosphoribosylaminoimidazolesuccinocarboxamide synthase activity Inferred from electronic annotation. Source: HAMAP
Complete GO annotation...

Sequences

	Sequence		Length	Mass (Da)
	A3QF29 [UniParc]. Last modified April 17, 2007. Version 1. Checksum: A891384AD48F4298	FASTA	368	41,550
	10 20 30 40 50 60 MNQSNKVLAV NDDLPIRTDK PVHSGKVRSV YWLTAEDSAR LIEQKGYDVP ADTPLAIMVI 70 80 90 100 110 120 SDRISAFDCI WQGENGLNGV PGKGAALNAI SNHWFKLFKE KGLADSHILD VPHPFVWIVQ 130 140 150 160 170 180 KAQPVMVEAI ARQYITGSMW RAYSKGERDF CGITLPEGLE KDQKLEEVLI TPSTKGVLTG 190 200 210 220 230 240 LEGVPEADDV NVSRADLERH LEGFNFHSKG DIDLYEKLLK EGFAVISEAL AEQDQIFVDT 250 260 270 280 290 300 KFEFGYVKDA SGQEKLIYMD EVGTPDSSRI WDGEARRNGK IVEKSKEGFR QWLLNHFPDP 310 320 330 340 350 360 DILLNKERMP ERFALARDNK LPTEVMMDIS NTYVGIAETI IGHKLHLSEN PRQEIIDILR DEYQLIQA

References

[1]

"Complete sequence of Shewanella loihica PV-4." Copeland A., Lucas S., Lapidus A., Barry K., Detter J.C., Glavina del Rio T., Hammon N., Israni S., Dalin E., Tice H., Pitluck S., Chain P., Malfatti S., Shin M., Vergez L., Schmutz J., Larimer F., Land M. , Hauser L., Kyrpides N., Mikhailova N., Romine M.F., Serres G., Fredrickson J., Tiedje J., Richardson P. Submitted (MAR-2007) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: ATCC BAA-1088 / PV-4.

Cross-references

Sequence databases
EMBL GenBank DDBJ	CP000606 Genomic DNA. Translation: ABO24077.1.
RefSeq	YP_001094336.1. NC_009092.1.
3D structure databases
ProteinModelPortal	A3QF29.
ModBase	Search...
Protein-protein interaction databases
STRING	A3QF29.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
GeneID	4923032.
GenomeReviews	Gene locus Shew_2211 in contig CP000606_GR.
KEGG	slo:Shew_2211.
NMPDR	fig|323850.3.peg.454.
PATRIC	23516293. VBISheLoi132094_2209.
Organism-specific databases
CMR	Search...
Phylogenomic databases
eggNOG	COG0152.
HOGENOM	HBG555040.
OMA	SSRIWDG.
PhylomeDB	A3QF29.
ProtClustDB	PRK13960.
Enzyme and pathway databases
BioCyc	SLOI323850:SHEW_2211-MONOMER.
Family and domain databases
HAMAP	MF_00137. SAICAR_synth. [Tree]
InterPro	IPR013816. ATP_grasp_subdomain_2. IPR014106. PurC_vibrio. IPR001636. SAICAR_synth. [Graphical view]
Gene3D	G3DSA:3.30.470.20. ATP_grasp_subdomain_2. 1 hit.
KO	K01923.
PANTHER	PTHR11609. SAICAR_synt. 1 hit.
Pfam	PF01259. SAICAR_synt. 1 hit. [Graphical view]
TIGRFAMs	TIGR02735. PurC_vibrio. 1 hit.
ProtoNet	Search...

Entry information

Entry name

A3QF29_SHELP

Accession

Primary (citable) accession number: A3QF29

Entry history

Integrated into UniProtKB/TrEMBL:	April 17, 2007
Last sequence update:	April 17, 2007
Last modified:	December 14, 2011
This is version 42 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)