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Protein

UvrABC system protein C

Gene

uvrC

Organism
Shewanella loihica (strain ATCC BAA-1088 / PV-4)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision.UniRule annotation

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionExcision nuclease
Biological processDNA damage, DNA excision, DNA repair, SOS response

Names & Taxonomyi

Protein namesi
Recommended name:
UvrABC system protein CUniRule annotation
Short name:
Protein UvrCUniRule annotation
Alternative name(s):
Excinuclease ABC subunit CUniRule annotation
Gene namesi
Name:uvrCUniRule annotation
Ordered Locus Names:Shew_1825
OrganismiShewanella loihica (strain ATCC BAA-1088 / PV-4)
Taxonomic identifieri323850 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaAlteromonadalesShewanellaceaeShewanella
Proteomesi
  • UP000001558 Componenti: Chromosome

Subcellular locationi

A3QDZ3:
  • Cytoplasm UniRule annotation

GO - Cellular componenti

Keywords - Cellular componenti

Cytoplasm

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_10000778381 – 609UvrABC system protein CAdd BLAST609

Interactioni

Subunit structurei

Interacts with UvrB in an incision complex.UniRule annotation

Protein-protein interaction databases

STRINGi323850.Shew_1825.

Structurei

3D structure databases

ProteinModelPortaliA3QDZ3.
SMRiA3QDZ3.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini16 – 94GIY-YIGUniRule annotationAdd BLAST79
Domaini203 – 238UVRUniRule annotationAdd BLAST36

Sequence similaritiesi

Belongs to the UvrC family.UniRule annotation

Phylogenomic databases

eggNOGiENOG4105CII. Bacteria.
COG0322. LUCA.
HOGENOMiHOG000279961.
KOiK03703.
OMAiLFPIRQC.
OrthoDBiPOG091H01BS.

Family and domain databases

Gene3Di3.40.1440.10. 1 hit.
4.10.860.10. 1 hit.
HAMAPiMF_00203. UvrC. 1 hit.
InterProiView protein in InterPro
IPR000305. GIY-YIG_endonuc.
IPR035901. GIY-YIG_endonuc_sf.
IPR003583. Hlx-hairpin-Hlx_DNA-bd_motif.
IPR010994. RuvA_2-like.
IPR001943. UVR_dom.
IPR036876. UVR_dom_sf.
IPR004791. UvrC.
IPR001162. UvrC_homol_region.
PfamiView protein in Pfam
PF01541. GIY-YIG. 1 hit.
PF02151. UVR. 1 hit.
PF08459. UvrC_HhH_N. 1 hit.
SMARTiView protein in SMART
SM00465. GIYc. 1 hit.
SM00278. HhH1. 2 hits.
SUPFAMiSSF46600. SSF46600. 1 hit.
SSF47781. SSF47781. 1 hit.
SSF82771. SSF82771. 1 hit.
TIGRFAMsiTIGR00194. uvrC. 1 hit.
PROSITEiView protein in PROSITE
PS50164. GIY_YIG. 1 hit.
PS50151. UVR. 1 hit.
PS50165. UVRC. 1 hit.

Sequencei

Sequence statusi: Complete.

A3QDZ3-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MTDSFNATQF LKTVSSSAGV YRMYDAQGVV IYVGKAKDLK KRLSSYFRRN
60 70 80 90 100
LPNVKTQALV SHIANIDVTL TPSETDALIL ENDYIKQYMP RYNVLLRDDK
110 120 130 140 150
SYPYIFLSGH RHPRLAYHRG PQREKGHYFG PYPNGGAVRE SLHLMQKLFP
160 170 180 190 200
IRQCDDLYYK ARSRPCLQYQ IARCSAPCVG KISDEDYAEQ VKLASLFLRG
210 220 230 240 250
KDQQVIATLV GKMEQAAMDL NYEDAARYRD QISALRRVAE QQEVSSDSGD
260 270 280 290 300
MDVIGAYYAS GIACFHLLFI RNGKIFGSRS YYPSVPDETE VSEVLRAFML
310 320 330 340 350
QFYLNVDSQR TLPREIVVSH EFEDIHELEE AIAQASNRRL LIKTKVRSER
360 370 380 390 400
ASFLRIADAN AKNAVETRLS HQNTVEERFL LLEEALEQSQ AINRMECFDI
410 420 430 440 450
SHTMGESTVA SCVVFNREGP SKGEYRRYNI SGITPGDDYA AMKQAIGRRF
460 470 480 490 500
DKIEADGKIP DILFIDGGMG QLRIAQKVVN EKFAHLDVAP TLIGVAKGEG
510 520 530 540 550
RKPGLETLIY GENEVAFSLP ADSGALHLIQ HIRDESHRFA ITGHRNKRQK
560 570 580 590 600
TRNTSTLESI PGVGPKRRKA LLQYLGGLQQ VKGASVAQLS KVPGISLEMA

QTIHDALRG
Length:609
Mass (Da):68,543
Last modified:April 17, 2007 - v1
Checksum:i55BC2D39DDF7C3CF
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP000606 Genomic DNA. Translation: ABO23691.1.
RefSeqiWP_011865623.1. NC_009092.1.

Genome annotation databases

EnsemblBacteriaiABO23691; ABO23691; Shew_1825.
KEGGislo:Shew_1825.

Similar proteinsi

Entry informationi

Entry nameiUVRC_SHELP
AccessioniPrimary (citable) accession number: A3QDZ3
Entry historyiIntegrated into UniProtKB/Swiss-Prot: May 20, 2008
Last sequence update: April 17, 2007
Last modified: October 25, 2017
This is version 72 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families