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A3QBZ9

- GLSA_SHELP

UniProt

A3QBZ9 - GLSA_SHELP

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Protein
Glutaminase
Gene
glsA, Shew_1126
Organism
Shewanella loihica (strain ATCC BAA-1088 / PV-4)
Status
Reviewed - Annotation score: 2 out of 5 - Protein inferred from homologyi

Functioni

Catalytic activityi

L-glutamine + H2O = L-glutamate + NH3.UniRule annotation

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Binding sitei63 – 631Substrate By similarity
Binding sitei114 – 1141Substrate By similarity
Binding sitei158 – 1581Substrate By similarity
Binding sitei165 – 1651Substrate By similarity
Binding sitei189 – 1891Substrate By similarity
Binding sitei240 – 2401Substrate By similarity
Binding sitei258 – 2581Substrate; via amide nitrogen By similarity

GO - Molecular functioni

  1. glutaminase activity Source: UniProtKB-HAMAP

GO - Biological processi

  1. glutamine metabolic process Source: InterPro
Complete GO annotation...

Keywords - Molecular functioni

Hydrolase

Enzyme and pathway databases

BioCyciSLOI323850:GHQJ-1151-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
Glutaminase (EC:3.5.1.2)
Gene namesi
Name:glsA
Ordered Locus Names:Shew_1126
OrganismiShewanella loihica (strain ATCC BAA-1088 / PV-4)
Taxonomic identifieri323850 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaAlteromonadalesShewanellaceaeShewanella
ProteomesiUP000001558: Chromosome

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 304304GlutaminaseUniRule annotation
PRO_1000048358Add
BLAST

Interactioni

Subunit structurei

Homotetramer By similarity.UniRule annotation

Protein-protein interaction databases

STRINGi323850.Shew_1126.

Structurei

3D structure databases

ProteinModelPortaliA3QBZ9.

Family & Domainsi

Sequence similaritiesi

Belongs to the glutaminase family.

Phylogenomic databases

eggNOGiCOG2066.
HOGENOMiHOG000216890.
KOiK01425.
OMAiMSIAVWS.
OrthoDBiEOG6N94BK.

Family and domain databases

Gene3Di3.40.710.10. 1 hit.
HAMAPiMF_00313. Glutaminase.
InterProiIPR012338. Beta-lactam/transpept-like.
IPR015868. Glutaminase.
[Graphical view]
PANTHERiPTHR12544. PTHR12544. 1 hit.
PfamiPF04960. Glutaminase. 1 hit.
[Graphical view]
SUPFAMiSSF56601. SSF56601. 1 hit.
TIGRFAMsiTIGR03814. Gln_ase. 1 hit.

Sequencei

Sequence statusi: Complete.

A3QBZ9-1 [UniParc]FASTAAdd to Basket

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MPQKDLLETI IEQVRPLLGK GKVADYIPAL AEVDPTKLGI AVTTIDGQTI    50
GAGDYLEPFS IQSISKVFSL TVALTLYEEA EIWSRVGKEP SGQSFNSLVQ 100
IELERGVPRN PFINAGALII ADLLQSRLGA PKHRMLEVVR KLSANPHVIY 150
DKRVAASEYE HSARNAAIAY LMKSFGNFNN DVDRVLRNYF HYCALKMSCA 200
DLSKAMLYLA NRGQSLSAEQ VVSPIQTRKL NALLATSGLY DGAGEFAYRV 250
GMPGKSGVGG GIIAVIPGDM SICVWSPELD KNGNSLAGTA ALEKLSQALG 300
RSIF 304
Length:304
Mass (Da):32,875
Last modified:April 17, 2007 - v1
Checksum:i72E3A74ED3255EED
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
CP000606 Genomic DNA. Translation: ABO22997.1.
RefSeqiYP_001093256.1. NC_009092.1.

Genome annotation databases

EnsemblBacteriaiABO22997; ABO22997; Shew_1126.
GeneIDi4924329.
KEGGislo:Shew_1126.
PATRICi23514031. VBISheLoi132094_1131.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
CP000606 Genomic DNA. Translation: ABO22997.1 .
RefSeqi YP_001093256.1. NC_009092.1.

3D structure databases

ProteinModelPortali A3QBZ9.
ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

STRINGi 323850.Shew_1126.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblBacteriai ABO22997 ; ABO22997 ; Shew_1126 .
GeneIDi 4924329.
KEGGi slo:Shew_1126.
PATRICi 23514031. VBISheLoi132094_1131.

Phylogenomic databases

eggNOGi COG2066.
HOGENOMi HOG000216890.
KOi K01425.
OMAi MSIAVWS.
OrthoDBi EOG6N94BK.

Enzyme and pathway databases

BioCyci SLOI323850:GHQJ-1151-MONOMER.

Family and domain databases

Gene3Di 3.40.710.10. 1 hit.
HAMAPi MF_00313. Glutaminase.
InterProi IPR012338. Beta-lactam/transpept-like.
IPR015868. Glutaminase.
[Graphical view ]
PANTHERi PTHR12544. PTHR12544. 1 hit.
Pfami PF04960. Glutaminase. 1 hit.
[Graphical view ]
SUPFAMi SSF56601. SSF56601. 1 hit.
TIGRFAMsi TIGR03814. Gln_ase. 1 hit.
ProtoNeti Search...

Publicationsi

  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: ATCC BAA-1088 / PV-4.

Entry informationi

Entry nameiGLSA_SHELP
AccessioniPrimary (citable) accession number: A3QBZ9
Entry historyi
Integrated into UniProtKB/Swiss-Prot: January 15, 2008
Last sequence update: April 17, 2007
Last modified: May 14, 2014
This is version 46 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3

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