A3QBR0 (A3QBR0_SHELP) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Recommended name:
DNA mismatch repair protein MutH HAMAP-Rule MF_00759

Alternative name(s):
Methyl-directed mismatch repair protein HAMAP-Rule MF_00759

Gene names

Name:	mutH HAMAP-Rule MF_00759
Ordered Locus Names:	Shew_1037

Organism

Shewanella loihica (strain ATCC BAA-1088 / PV-4) [Complete proteome] [HAMAP] EMBL ABO22908.1

Taxonomic identifier

323850 [NCBI]

Taxonomic lineage

cellular organisms › Bacteria › Proteobacteria › Gammaproteobacteria › Alteromonadales › Shewanellaceae › Shewanella › Shewanella loihica

Protein attributes

Sequence length	223 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Function	Sequence-specific endonuclease that cleaves unmethylated GATC sequences. It is involved in DNA mismatch repair By similarity. HAMAP-Rule MF_00759 SAAS SAAS011337
Subcellular location	Cytoplasm By similarity HAMAP-Rule MF_00759 SAAS SAAS011337.
Sequence similarities	Belongs to the MutH family. HAMAP-Rule MF_00759

Ontologies

Keywords
Biological process	DNA damage DNA repair HAMAP-Rule MF_00759 SAAS SAAS011337
Cellular component	Cytoplasm HAMAP-Rule MF_00759 SAAS SAAS011337
Molecular function	Endonuclease HAMAP-Rule MF_00759 SAAS SAAS011337 Hydrolase Nuclease
Technical term	Complete proteome
Gene Ontology (GO)
Biological_process	DNA modification Inferred from electronic annotation. Source: InterPro DNA repair Inferred from electronic annotation. Source: UniProtKB-KW nucleic acid phosphodiester bond hydrolysis Inferred from electronic annotation. Source: GOC
Cellular_component	cytoplasm Inferred from electronic annotation. Source: UniProtKB-SubCell
Molecular_function	DNA binding Inferred from electronic annotation. Source: InterPro endonuclease activity Inferred from electronic annotation. Source: UniProtKB-KW
Complete GO annotation...

Sequences

	Sequence		Length	Mass (Da)
	A3QBR0 [UniParc]. Last modified April 17, 2007. Version 1. Checksum: 7F348EEF3813400F	FASTA	223	25,238
	10 20 30 40 50 60 MKSKILPPES LDELMQRAQE MAGLTLGQLA ELHHVAVPSN LKRDKGWIGQ LIELELGATA 70 80 90 100 110 120 GSKPEQDFLH LGVELKTIPV DESGKPLETT YVTVAPLMNI NGLRWQESLV YHKLQRVLWI 130 140 150 160 170 180 PVEGIRHKPI GERRIGSPIL WTPSEEEMAQ IRQDWEEIME LIALGKVEQI TARHGEVLQL 190 200 210 220 RPKGANSRAL TQSIAQDGQV KLTNPRGFYL KIPFTQQILS RYF

References

[1]

"Complete sequence of Shewanella loihica PV-4." US DOE Joint Genome Institute Copeland A., Lucas S., Lapidus A., Barry K., Detter J.C., Glavina del Rio T., Hammon N., Israni S., Dalin E., Tice H., Pitluck S., Chain P., Malfatti S., Shin M., Vergez L., Schmutz J., Larimer F., Land M. , Hauser L., Kyrpides N., Mikhailova N., Romine M.F., Serres G., Fredrickson J., Tiedje J., Richardson P. Submitted (MAR-2007) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: ATCC BAA-1088 / PV-4.

Cross-references

Sequence databases
EMBL GenBank DDBJ	CP000606 Genomic DNA. Translation: ABO22908.1.
RefSeq	YP_001093167.1. NC_009092.1.
3D structure databases
ProteinModelPortal	A3QBR0.
SMR	A3QBR0. Positions 7-223.
ModBase	Search...
Protein-protein interaction databases
STRING	323850.Shew_1037.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
EnsemblBacteria	ABO22908; ABO22908; Shew_1037.
GeneID	4920592.
KEGG	slo:Shew_1037.
PATRIC	23513847. VBISheLoi132094_1041.
Organism-specific databases
CMR	Search...
Phylogenomic databases
eggNOG	COG3066.
HOGENOM	HOG000271839.
KO	K03573.
OMA	LRPKGAN.
ProtClustDB	PRK05070.
Enzyme and pathway databases
BioCyc	SLOI323850:GHQJ-1060-MONOMER.
Family and domain databases
Gene3D	3.40.600.10. 1 hit.
HAMAP	MF_00759. MutH.
InterPro	IPR004230. DNA_mismatch_repair_MutH. IPR011337. DNA_rep_MutH/RE_typeII. IPR011335. Restrct_endonuc-II-like. [Graphical view]
Pfam	PF02976. MutH. 1 hit. [Graphical view]
SMART	SM00927. MutH. 1 hit. [Graphical view]
SUPFAM	SSF52980. Restrict_endonuc_II-like_core. 1 hit.
TIGRFAMs	TIGR02248. mutH_TIGR. 1 hit.
ProtoNet	Search...

Entry information

Entry name

A3QBR0_SHELP

Accession

Primary (citable) accession number: A3QBR0

Entry history

Integrated into UniProtKB/TrEMBL:	April 17, 2007
Last sequence update:	April 17, 2007
Last modified:	May 29, 2013
This is version 50 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)