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Protein

DNA mismatch repair protein MutH

Gene

mutH

Organism
Shewanella loihica (strain ATCC BAA-1088 / PV-4)
Status
Unreviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

Sequence-specific endonuclease that cleaves unmethylated GATC sequences. It is involved in DNA mismatch repair.UniRule annotationSAAS annotation

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionEndonucleaseUniRule annotationSAAS annotation, Hydrolase, Nuclease
Biological processDNA damage, DNA repairUniRule annotationSAAS annotation

Names & Taxonomyi

Protein namesi
Recommended name:
DNA mismatch repair protein MutHUniRule annotationSAAS annotation
Alternative name(s):
Methyl-directed mismatch repair proteinUniRule annotation
Gene namesi
Name:mutHUniRule annotation
Ordered Locus Names:Shew_1037Imported
OrganismiShewanella loihica (strain ATCC BAA-1088 / PV-4)Imported
Taxonomic identifieri323850 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaAlteromonadalesShewanellaceaeShewanella
Proteomesi
  • UP000001558 Componenti: Chromosome

Subcellular locationi

  • Cytoplasm UniRule annotationSAAS annotation

GO - Cellular componenti

Keywords - Cellular componenti

CytoplasmUniRule annotationSAAS annotation

Interactioni

Protein-protein interaction databases

STRINGi323850.Shew_1037.

Structurei

3D structure databases

ProteinModelPortaliA3QBR0.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini56 – 154MutHInterPro annotationAdd BLAST99

Sequence similaritiesi

Belongs to the MutH family.UniRule annotationSAAS annotation

Phylogenomic databases

eggNOGiENOG4105IRT. Bacteria.
COG3066. LUCA.
HOGENOMiHOG000271839.
KOiK03573.
OMAiPPDLKRD.
OrthoDBiPOG091H04RA.

Family and domain databases

CDDicd00583. MutH_Sau3AI. 1 hit.
Gene3Di3.40.600.10. 1 hit.
HAMAPiMF_00759. MutH. 1 hit.
InterProiView protein in InterPro
IPR004230. DNA_mismatch_repair_MutH.
IPR011337. DNA_rep_MutH/RE_typeII.
IPR011335. Restrct_endonuc-II-like.
PfamiView protein in Pfam
PF02976. MutH. 1 hit.
SMARTiView protein in SMART
SM00927. MutH. 1 hit.
SUPFAMiSSF52980. SSF52980. 1 hit.
TIGRFAMsiTIGR02248. mutH_TIGR. 1 hit.

Sequencei

Sequence statusi: Complete.

A3QBR0-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MKSKILPPES LDELMQRAQE MAGLTLGQLA ELHHVAVPSN LKRDKGWIGQ
60 70 80 90 100
LIELELGATA GSKPEQDFLH LGVELKTIPV DESGKPLETT YVTVAPLMNI
110 120 130 140 150
NGLRWQESLV YHKLQRVLWI PVEGIRHKPI GERRIGSPIL WTPSEEEMAQ
160 170 180 190 200
IRQDWEEIME LIALGKVEQI TARHGEVLQL RPKGANSRAL TQSIAQDGQV
210 220
KLTNPRGFYL KIPFTQQILS RYF
Length:223
Mass (Da):25,238
Last modified:April 17, 2007 - v1
Checksum:i7F348EEF3813400F
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP000606 Genomic DNA. Translation: ABO22908.1.
RefSeqiWP_011864841.1. NC_009092.1.

Genome annotation databases

EnsemblBacteriaiABO22908; ABO22908; Shew_1037.
KEGGislo:Shew_1037.

Similar proteinsi

Entry informationi

Entry nameiA3QBR0_SHELP
AccessioniPrimary (citable) accession number: A3QBR0
Entry historyiIntegrated into UniProtKB/TrEMBL: April 17, 2007
Last sequence update: April 17, 2007
Last modified: September 27, 2017
This is version 80 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported