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Protein

DNA mismatch repair protein MutH

Gene

mutH

Organism
Shewanella loihica (strain ATCC BAA-1088 / PV-4)
Status
Unreviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

Sequence-specific endonuclease that cleaves unmethylated GATC sequences. It is involved in DNA mismatch repair.UniRule annotationSAAS annotation

GO - Molecular functioni

  1. DNA binding Source: InterPro
  2. endonuclease activity Source: UniProtKB-HAMAP

GO - Biological processi

  1. DNA modification Source: InterPro
  2. mismatch repair Source: UniProtKB-HAMAP
Complete GO annotation...

Keywords - Molecular functioni

EndonucleaseUniRule annotationSAAS annotation, Hydrolase, Nuclease

Keywords - Biological processi

DNA damage, DNA repairUniRule annotationSAAS annotation

Enzyme and pathway databases

BioCyciSLOI323850:GHQJ-1060-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
DNA mismatch repair protein MutHUniRule annotationSAAS annotation
Alternative name(s):
Methyl-directed mismatch repair proteinUniRule annotation
Gene namesi
Name:mutHUniRule annotation
Ordered Locus Names:Shew_1037Imported
OrganismiShewanella loihica (strain ATCC BAA-1088 / PV-4)Imported
Taxonomic identifieri323850 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaAlteromonadalesShewanellaceaeShewanella
ProteomesiUP000001558 Componenti: Chromosome

Subcellular locationi

Cytoplasm UniRule annotationSAAS annotation

GO - Cellular componenti

  1. cytoplasm Source: UniProtKB-SubCell
Complete GO annotation...

Keywords - Cellular componenti

CytoplasmUniRule annotationSAAS annotation

Interactioni

Protein-protein interaction databases

STRINGi323850.Shew_1037.

Structurei

3D structure databases

ProteinModelPortaliA3QBR0.
SMRiA3QBR0. Positions 7-223.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the MutH family.UniRule annotation

Phylogenomic databases

eggNOGiCOG3066.
HOGENOMiHOG000271839.
KOiK03573.
OMAiLRPKGAN.
OrthoDBiEOG6CGCC0.

Family and domain databases

Gene3Di3.40.600.10. 1 hit.
HAMAPiMF_00759. MutH.
InterProiIPR004230. DNA_mismatch_repair_MutH.
IPR011337. DNA_rep_MutH/RE_typeII.
IPR011335. Restrct_endonuc-II-like.
[Graphical view]
PfamiPF02976. MutH. 1 hit.
[Graphical view]
SMARTiSM00927. MutH. 1 hit.
[Graphical view]
SUPFAMiSSF52980. SSF52980. 1 hit.
TIGRFAMsiTIGR02248. mutH_TIGR. 1 hit.

Sequencei

Sequence statusi: Complete.

A3QBR0-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MKSKILPPES LDELMQRAQE MAGLTLGQLA ELHHVAVPSN LKRDKGWIGQ
60 70 80 90 100
LIELELGATA GSKPEQDFLH LGVELKTIPV DESGKPLETT YVTVAPLMNI
110 120 130 140 150
NGLRWQESLV YHKLQRVLWI PVEGIRHKPI GERRIGSPIL WTPSEEEMAQ
160 170 180 190 200
IRQDWEEIME LIALGKVEQI TARHGEVLQL RPKGANSRAL TQSIAQDGQV
210 220
KLTNPRGFYL KIPFTQQILS RYF
Length:223
Mass (Da):25,238
Last modified:April 17, 2007 - v1
Checksum:i7F348EEF3813400F
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP000606 Genomic DNA. Translation: ABO22908.1.
RefSeqiYP_001093167.1. NC_009092.1.

Genome annotation databases

EnsemblBacteriaiABO22908; ABO22908; Shew_1037.
KEGGislo:Shew_1037.
PATRICi23513847. VBISheLoi132094_1041.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP000606 Genomic DNA. Translation: ABO22908.1.
RefSeqiYP_001093167.1. NC_009092.1.

3D structure databases

ProteinModelPortaliA3QBR0.
SMRiA3QBR0. Positions 7-223.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi323850.Shew_1037.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiABO22908; ABO22908; Shew_1037.
KEGGislo:Shew_1037.
PATRICi23513847. VBISheLoi132094_1041.

Phylogenomic databases

eggNOGiCOG3066.
HOGENOMiHOG000271839.
KOiK03573.
OMAiLRPKGAN.
OrthoDBiEOG6CGCC0.

Enzyme and pathway databases

BioCyciSLOI323850:GHQJ-1060-MONOMER.

Family and domain databases

Gene3Di3.40.600.10. 1 hit.
HAMAPiMF_00759. MutH.
InterProiIPR004230. DNA_mismatch_repair_MutH.
IPR011337. DNA_rep_MutH/RE_typeII.
IPR011335. Restrct_endonuc-II-like.
[Graphical view]
PfamiPF02976. MutH. 1 hit.
[Graphical view]
SMARTiSM00927. MutH. 1 hit.
[Graphical view]
SUPFAMiSSF52980. SSF52980. 1 hit.
TIGRFAMsiTIGR02248. mutH_TIGR. 1 hit.
ProtoNetiSearch...

Publicationsi

  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: ATCC BAA-1088 / PV-4Imported.

Entry informationi

Entry nameiA3QBR0_SHELP
AccessioniPrimary (citable) accession number: A3QBR0
Entry historyi
Integrated into UniProtKB/TrEMBL: April 17, 2007
Last sequence update: April 17, 2007
Last modified: April 1, 2015
This is version 62 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported

External Data

Dasty 3

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into Uniref entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.