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Protein

Bis(5'-nucleosyl)-tetraphosphatase, symmetrical

Gene

apaH

Organism
Shewanella loihica (strain ATCC BAA-1088 / PV-4)
Status
Reviewed-Annotation score: -Protein inferred from homologyi

Functioni

Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP.UniRule annotation

Catalytic activityi

P1,P4-bis(5'-adenosyl) tetraphosphate + H2O = 2 ADP.UniRule annotation

GO - Molecular functioni

Keywordsi

Molecular functionHydrolase

Enzyme and pathway databases

BioCyciSLOI323850:G1G8D-927-MONOMER

Names & Taxonomyi

Protein namesi
Recommended name:
Bis(5'-nucleosyl)-tetraphosphatase, symmetricalUniRule annotation (EC:3.6.1.41UniRule annotation)
Alternative name(s):
Ap4A hydrolaseUniRule annotation
Diadenosine 5',5'''-P1,P4-tetraphosphate pyrophosphohydrolaseUniRule annotation
Diadenosine tetraphosphataseUniRule annotation
Gene namesi
Name:apaHUniRule annotation
Ordered Locus Names:Shew_0877
OrganismiShewanella loihica (strain ATCC BAA-1088 / PV-4)
Taxonomic identifieri323850 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaAlteromonadalesShewanellaceaeShewanella
Proteomesi
  • UP000001558 Componenti: Chromosome

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_10000120911 – 274Bis(5'-nucleosyl)-tetraphosphatase, symmetricalAdd BLAST274

Interactioni

Protein-protein interaction databases

STRINGi323850.Shew_0877

Structurei

3D structure databases

ProteinModelPortaliA3QBA1
SMRiA3QBA1
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the Ap4A hydrolase family.UniRule annotation

Phylogenomic databases

eggNOGiENOG4105DDT Bacteria
COG0639 LUCA
HOGENOMiHOG000251871
KOiK01525
OMAiMPWFDVP
OrthoDBiPOG091H0691

Family and domain databases

CDDicd07422 MPP_ApaH, 1 hit
Gene3Di3.60.21.10, 1 hit
HAMAPiMF_00199 ApaH, 1 hit
InterProiView protein in InterPro
IPR004617 ApaH
IPR004843 Calcineurin-like_PHP_ApaH
IPR029052 Metallo-depent_PP-like
PfamiView protein in Pfam
PF00149 Metallophos, 1 hit
PIRSFiPIRSF000903 B5n-ttraPtase_sm, 1 hit
TIGRFAMsiTIGR00668 apaH, 1 hit

Sequencei

Sequence statusi: Complete.

A3QBA1-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MATYFVGDIQ GCFDELHVLL AKVDFNPSKD ELWVVGDMVA RGTQSLETLR
60 70 80 90 100
YLKGLEGSVK PVLGNHDLHL MALHGKVKRV NPKDNLGALL AAPDLNQLID
110 120 130 140 150
WLRLQPLARE HKAHSVLMAH AGIPPQWDVK TVLKESRKVQ EALARDDYIE
160 170 180 190 200
HLIAKMYTNS VSEWSPETKG LKRLVYTINA LTRMRFLHSD GRLNFDCKLP
210 220 230 240 250
PAKGEKEGLI PWFKQPGRAM KGHTLVFGHW AALMGEVNQP GLQALDTGCC
260 270
WGQYLTLWHL ESNQKITQNK LKKS
Length:274
Mass (Da):30,930
Last modified:April 17, 2007 - v1
Checksum:i4B1C2EBD0610490F
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP000606 Genomic DNA Translation: ABO22749.1
RefSeqiWP_011864683.1, NC_009092.1

Genome annotation databases

EnsemblBacteriaiABO22749; ABO22749; Shew_0877
KEGGislo:Shew_0877

Similar proteinsi

Entry informationi

Entry nameiAPAH_SHELP
AccessioniPrimary (citable) accession number: A3QBA1
Entry historyiIntegrated into UniProtKB/Swiss-Prot: January 15, 2008
Last sequence update: April 17, 2007
Last modified: March 28, 2018
This is version 67 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome
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Main funding by: National Institutes of Health