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A3QAF4 (A3QAF4_SHELP) Unreviewed, UniProtKB/TrEMBL

Last modified December 14, 2011. Version 48. Feed History...

Clusters with 100%, 90%, 50% identity | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein namesRecommended name:
N-succinylglutamate 5-semialdehyde dehydrogenase HAMAP MF_01174
EC=1.2.1.71 HAMAP MF_01174
Alternative name(s):
Succinylglutamic semialdehyde dehydrogenase HAMAP MF_01174
Gene names
Name:astD HAMAP MF_01174
Ordered Locus Names:Shew_0580
OrganismShewanella loihica (strain ATCC BAA-1088 / PV-4) [Complete proteome] [HAMAP] EMBL ABO22452.1
Taxonomic identifier323850 [NCBI]
Taxonomic lineageBacteria › Proteobacteria › Gammaproteobacteria › Alteromonadales › Shewanellaceae › Shewanella

Protein attributes

Sequence length487 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

Catalyzes the NAD-dependent reduction of succinylglutamate semialdehyde into succinylglutamate By similarity. HAMAP MF_01174

Catalytic activity

N-succinyl-L-glutamate 5-semialdehyde + NAD+ + H2O = N-succinyl-L-glutamate + NADH. HAMAP MF_01174

Pathway

Amino-acid degradation; L-arginine degradation via AST pathway; L-glutamate and succinate from L-arginine: step 4/5. HAMAP MF_01174

Sequence similarities

Belongs to the aldehyde dehydrogenase family. AstD subfamily. HAMAP MF_01174

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Regions

Nucleotide binding221 – 2266NAD By similarity HAMAP MF_01174

Sites

Active site2441 By similarity HAMAP MF_01174
Active site2781 By similarity HAMAP MF_01174

Sequences

Sequence LengthMass (Da)Tools
A3QAF4 [UniParc].

Last modified April 17, 2007. Version 1.
Checksum: B8D1982AB6339A6B

FASTA48751,866
        10         20         30         40         50         60 
MMSQFINGQW VAGLGHDVVS KNPANQEVIW ESKTATPEQV NAAVEAARAA QFDWFMLGFD 

        70         80         90        100        110        120 
ARLAIVEAYR DQLEAHKGDI AEVIAQETGK PQWETATEAG AMIGKIGLSV AAYHKRTGTS 

       130        140        150        160        170        180 
ENDTPAGRAV LRHKPHGVVA VFGPYNFPGH LPNGHIVPAL LAGNTVVFKP SELTPKTAEL 

       190        200        210        220        230        240 
MLKLWEKAGL PAGVINLVQG EVETGKALAS HPQIDGLFFT GSSRTGHILH QQYAGHPGKI 

       250        260        270        280        290        300 
LALEMGGNNP LIIKGVKDTL AAVHDIIQSA YISSGQRCTC ARRLYVEKGA EGDALLAKLA 

       310        320        330        340        350        360 
EAVKQIKVGP WNAQPQPFMG SMISEAAAKG MVEAQRNLIN LGGTPLVELK HLEAGTGLVS 

       370        380        390        400        410        420 
PGLIDVTQVI ELPDEEYFGP LLQVVRYTDF DEAIKLANDT RYGLSAGILA DSREDYDYFL 

       430        440        450        460        470        480 
ARIRAGIVNW NKQITGASGS APFGGVGASG NHRASAFYAA DYCAYPVASV EADALAMPAS 


LSPGLTL

« Hide

References

[1]"Complete sequence of Shewanella loihica PV-4."
Copeland A., Lucas S., Lapidus A., Barry K., Detter J.C., Glavina del Rio T., Hammon N., Israni S., Dalin E., Tice H., Pitluck S., Chain P., Malfatti S., Shin M., Vergez L., Schmutz J., Larimer F., Land M. expand/collapse author list , Hauser L., Kyrpides N., Mikhailova N., Romine M.F., Serres G., Fredrickson J., Tiedje J., Richardson P.
Submitted (MAR-2007) to the EMBL/GenBank/DDBJ databases
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: ATCC BAA-1088 / PV-4.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ		CP000606 Genomic DNA. Translation: ABO22452.1.
RefSeqYP_001092711.1. NC_009092.1.

3D structure databases

ProteinModelPortalA3QAF4.
ModBaseSearch...

Protein-protein interaction databases

STRINGA3QAF4.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

GeneID4923603.
GenomeReviewsGene locus Shew_0580 in contig CP000606_GR.
KEGGslo:Shew_0580.
NMPDRfig|323850.3.peg.1543.
PATRIC23512937. VBISheLoi132094_0587.

Organism-specific databases

CMRSearch...

Phylogenomic databases

eggNOGCOG1012.
HOGENOMHBG752218.
OMATHYIAGN.
PhylomeDBA3QAF4.
ProtClustDBPRK09457.

Enzyme and pathway databases

BioCycSLOI323850:SHEW_0580-MONOMER.

Family and domain databases

HAMAPMF_01174. Aldedh_AstD.
[Tree]
InterProIPR016161. Ald_DH/histidinol_DH.
IPR016163. Ald_DH_C.
IPR016160. Ald_DH_CS.
IPR016162. Ald_DH_N.
IPR015590. Aldehyde_DH_dom.
IPR017649. SuccinylGlu_semiald_DH_AstD.
[Graphical view]
Gene3DG3DSA:3.40.309.10. Aldehyde_dehydrogenase_C. 1 hit.
G3DSA:3.40.605.10. Aldehyde_dehydrogenase_N. 1 hit.
KOK06447.
PANTHERPTHR11699:SF24. PTHR11699:SF24. 1 hit.
PfamPF00171. Aldedh. 1 hit.
[Graphical view]
SUPFAMSSF53720. Aldehyde_DH/Histidinol_DH. 1 hit.
TIGRFAMsTIGR03240. Arg_catab_astD. 1 hit.
PROSITEPS00070. ALDEHYDE_DEHYDR_CYS. 1 hit.
PS00687. ALDEHYDE_DEHYDR_GLU. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameA3QAF4_SHELP
AccessionPrimary (citable) accession number: A3QAF4
Entry history
Integrated into UniProtKB/TrEMBL: April 17, 2007
Last sequence update: April 17, 2007
Last modified: December 14, 2011
This is version 48 of the entry and version 1 of the sequence. [Complete history]
Entry statusUnreviewed (UniProtKB/TrEMBL)
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info