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A3PZU7 (A3PZU7_MYCSJ) Unreviewed, UniProtKB/TrEMBL

Last modified December 14, 2011. Version 41. Feed History...

Clusters with 100%, 90%, 50% identity | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein namesSubmitted name:
Dihydrodipicolinate synthase EMBL ABN98424.1
Gene names
Ordered Locus Names:Mjls_2643
OrganismMycobacterium sp. (strain JLS) [Complete proteome] [HAMAP]
Taxonomic identifier164757 [NCBI]
Taxonomic lineageBacteria › Actinobacteria › Actinobacteridae › Actinomycetales › Corynebacterineae › Mycobacteriaceae › Mycobacterium

Protein attributes

Sequence length316 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Catalytic activity

L-aspartate 4-semialdehyde + pyruvate = dihydrodipicolinate + 2 H2O. SAAS SAAS005263

Pathway

Amino-acid biosynthesis; L-lysine biosynthesis via DAP pathway; (S)-tetrahydrodipicolinate from L-aspartate: step 3/4. SAAS SAAS005263

Subunit structure

Homotetramer By similarity. SAAS SAAS005263

Subcellular location

Cytoplasm By similarity SAAS SAAS005263.

Ontologies

Keywords
   Biological processAmino-acid biosynthesis
Diaminopimelate biosynthesis SAAS SAAS005263
Lysine biosynthesis SAAS SAAS005263
   Cellular componentCytoplasm SAAS SAAS005263
   LigandSchiff base SAAS SAAS005263
   Molecular functionLyase SAAS SAAS005263
   Technical termComplete proteome
Gene Ontology (GO)
   Biological processdiaminopimelate biosynthetic process

Inferred from electronic annotation. Source: HAMAP

   Cellular componentcytoplasm

Inferred from electronic annotation. Source: UniProtKB-SubCell

   Molecular functiondihydrodipicolinate synthase activity

Inferred from electronic annotation. Source: HAMAP

Complete GO annotation...

Sequences

Sequence LengthMass (Da)Tools
A3PZU7 [UniParc].

Last modified April 3, 2007. Version 1.
Checksum: AE2B5D4143BA45C7

FASTA31633,958
        10         20         30         40         50         60 
MTARRDPHSI RGSITPLMTP FTDDGAVDHR SLANLVNWQL ASGSHGISIG GSTGEPGAQS 

        70         80         90        100        110        120 
VAERLAAIAT VMKSVSGRAP VVAGTGTAKL DETIELTGRA AELGIDAALV ITPYYARPTQ 

       130        140        150        160        170        180 
EALYRWYKTV AEEYPDLPIL AYNVPVRTAV DLAPETIARL YRDVENFVGV KETTKDFEHF 

       190        200        210        220        230        240 
SRVMHLCGPD IIVWSGIELL CLPLLALGGT GFLSATANIA PAAHARMYEL WIAGAHEEAR 

       250        260        270        280        290        300 
AIHYGLHPLV DLLFVETNPA PGKWLLKDLG LIASDHVRPP LITPTPGALE RIAVLRRAGE 

       310 
KFLTPVGDFA LEGAFA

« Hide

References

[1]"Complete sequence of Mycobacterium sp. JLS."
Copeland A., Lucas S., Lapidus A., Barry K., Detter J.C., Glavina del Rio T., Hammon N., Israni S., Dalin E., Tice H., Pitluck S., Chain P., Malfatti S., Shin M., Vergez L., Schmutz J., Larimer F., Land M. expand/collapse author list , Hauser L., Kyrpides N., Mikhailova N., Miller C.D., Anderson A.J., Sims R.C., Richardson P.
Submitted (FEB-2007) to the EMBL/GenBank/DDBJ databases
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: JLS.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ		CP000580 Genomic DNA. Translation: ABN98424.1.
RefSeqYP_001070915.1. NC_009077.1.

3D structure databases

ProteinModelPortalA3PZU7.
ModBaseSearch...

Protein-protein interaction databases

STRINGA3PZU7.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaEBMYCT00000048226; EBMYCP00000046507; EBMYCG00000048221.
GeneID4878358.
GenomeReviewsGene locus Mjls_2643 in contig CP000580_GR.
KEGGmjl:Mjls_2643.
PATRIC18091445. VBIMycSp51234_2658.

Organism-specific databases

CMRSearch...

Phylogenomic databases

eggNOGCOG0329.
GeneTreeEBGT00050000016215.
HOGENOMHBG358848.
OMAGSTNHAE.
PhylomeDBA3PZU7.
ProtClustDBCLSK955639.

Family and domain databases

InterProIPR013785. Aldolase_TIM.
IPR002220. Dihydrodipicolinate_synth-like.
IPR020625. Dihydrodipicolinate_synth_AS.
IPR005263. Dihydrodipicolinate_synth_DapA.
[Graphical view]
Gene3DG3DSA:3.20.20.70. Aldolase_TIM. 1 hit.
KOK01714.
PANTHERPTHR12128. DHDPS. 1 hit.
PfamPF00701. DHDPS. 1 hit.
[Graphical view]
PIRSFPIRSF001365. DHDPS. 1 hit.
PRINTSPR00146. DHPICSNTHASE.
TIGRFAMsTIGR00674. DapA. 1 hit.
PROSITEPS00666. DHDPS_2. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameA3PZU7_MYCSJ
AccessionPrimary (citable) accession number: A3PZU7
Entry history
Integrated into UniProtKB/TrEMBL: April 3, 2007
Last sequence update: April 3, 2007
Last modified: December 14, 2011
This is version 41 of the entry and version 1 of the sequence. [Complete history]
Entry statusUnreviewed (UniProtKB/TrEMBL)
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