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Protein

Probable malate:quinone oxidoreductase

Gene

mqo

Organism
Mycobacterium sp. (strain JLS)
Status
Reviewed-Annotation score: -Protein inferred from homologyi

Functioni

Catalytic activityi

(S)-malate + a quinone = oxaloacetate + reduced quinone.UniRule annotation

Cofactori

FADUniRule annotation

Pathwayi: tricarboxylic acid cycle

This protein is involved in step 1 of the subpathway that synthesizes oxaloacetate from (S)-malate (quinone route).UniRule annotation
Proteins known to be involved in this subpathway in this organism are:
  1. Probable malate:quinone oxidoreductase (mqo)
This subpathway is part of the pathway tricarboxylic acid cycle, which is itself part of Carbohydrate metabolism.
View all proteins of this organism that are known to be involved in the subpathway that synthesizes oxaloacetate from (S)-malate (quinone route), the pathway tricarboxylic acid cycle and in Carbohydrate metabolism.

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionOxidoreductase
Biological processTricarboxylic acid cycle
LigandFAD, Flavoprotein

Enzyme and pathway databases

UniPathwayiUPA00223; UER01008

Names & Taxonomyi

Protein namesi
Recommended name:
Probable malate:quinone oxidoreductaseUniRule annotation (EC:1.1.5.4UniRule annotation)
Alternative name(s):
MQOUniRule annotation
Malate dehydrogenase [quinone]UniRule annotation
Gene namesi
Name:mqoUniRule annotation
Ordered Locus Names:Mjls_2052
OrganismiMycobacterium sp. (strain JLS)
Taxonomic identifieri164757 [NCBI]
Taxonomic lineageiBacteriaActinobacteriaCorynebacterialesMycobacteriaceaeMycobacterium

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00003255021 – 516Probable malate:quinone oxidoreductaseAdd BLAST516

Proteomic databases

PRIDEiA3PY62

Family & Domainsi

Sequence similaritiesi

Belongs to the MQO family.UniRule annotation

Phylogenomic databases

eggNOGiENOG4105DWT Bacteria
COG0579 LUCA
HOGENOMiHOG000109379
KOiK00116
OMAiEPIAATK
OrthoDBiPOG091H0B7C

Family and domain databases

Gene3Di3.50.50.60, 2 hits
HAMAPiMF_00212 MQO, 1 hit
InterProiView protein in InterPro
IPR036188 FAD/NAD-bd_sf
IPR006231 MQO
PfamiView protein in Pfam
PF06039 Mqo, 1 hit
SUPFAMiSSF51905 SSF51905, 1 hit
TIGRFAMsiTIGR01320 mal_quin_oxido, 1 hit

Sequencei

Sequence statusi: Complete.

A3PY62-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MSDAQVAKTD VVLVGAGIMS ATLSALIKLL EPNWSITLIE RLDGAAAESS
60 70 80 90 100
DPWNNAGTGH SALCELNYTP EGPGGSIDIT KAVHVNEQFQ VSRQFWTYAV
110 120 130 140 150
ENGVLPDVRN FINPIPHVSF VSGARNVEYL RARYDALVPN PLFATMEYID
160 170 180 190 200
DRDEFARRLP FMADKRDFRE PVALNWSQDG TDIDFGSLSR QLIGYTAQRG
210 220 230 240 250
MTTLFGHEVR DLDKQSDGSW SVKVVNRRTG AKRKLNAKFV FVGAGGGALP
260 270 280 290 300
LLQKAGIEEA KGFGGFPVGG QWLRTGNPEL TARHQAKVYG MPPLGAPPMS
310 320 330 340 350
VPHLDTRVIN GKSWLLFGPF AGWSPKFLKQ GKVTDLPFSV KPNNLASMLG
360 370 380 390 400
VGLTEMGLLK YLIGQLLLSE ADRVETLRNF APSARDSDWE LDIAGQRVQV
410 420 430 440 450
IRRKGKGGVL EFGTTVLAAK DGSIAGLLGA SPGASTAVPA MLDVMERCFG
460 470 480 490 500
DRYTAWLPKL KEIVPSLGTK LSDEPKLFQE IWAHGTKVLK LDHPAAGLPV
510
AGTDTEHREP ATTVTA
Length:516
Mass (Da):56,003
Last modified:April 3, 2007 - v1
Checksum:iEEC9685C404ACFEF
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP000580 Genomic DNA Translation: ABN97839.1
RefSeqiWP_011559467.1, NC_009077.1

Genome annotation databases

EnsemblBacteriaiABN97839; ABN97839; Mjls_2052
GeneIDi32422641
KEGGimjl:Mjls_2052

Similar proteinsi

Entry informationi

Entry nameiMQO_MYCSJ
AccessioniPrimary (citable) accession number: A3PY62
Entry historyiIntegrated into UniProtKB/Swiss-Prot: March 18, 2008
Last sequence update: April 3, 2007
Last modified: May 23, 2018
This is version 70 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

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