A3PXU9 (A3PXU9_MYCSJ) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Recommended name:
[Protein-PII] uridylyltransferase HAMAP MF_00277
Short name=PII uridylyl-transferase HAMAP MF_00277
EC=2.7.7.59 HAMAP MF_00277

Alternative name(s):
UTase HAMAP MF_00277
Uridylyl-removing enzyme HAMAP MF_00277

Gene names

Name:	glnD HAMAP MF_00277
Ordered Locus Names:	Mjls_1938

Organism

Mycobacterium sp. (strain JLS) [Complete proteome] [HAMAP]

Taxonomic identifier

164757 [NCBI]

Taxonomic lineage

Bacteria › Actinobacteria › Actinobacteridae › Actinomycetales › Corynebacterineae › Mycobacteriaceae › Mycobacterium

Protein attributes

Sequence length	837 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Function	Modifies, by uridylylation or deuridylylation the PII (glnB) regulatory protein By similarity. HAMAP MF_00277 SAAS SAAS002912
Catalytic activity	UTP + [protein-PII] = diphosphate + uridylyl-[protein-PII]. HAMAP MF_00277 SAAS SAAS002912
Sequence similarities	Belongs to the glnD family. HAMAP MF_00277

Ontologies

Keywords
Molecular function	Hydrolase EMBL ABN97726.1 Nucleotidyltransferase HAMAP MF_00277 SAAS SAAS002912 EMBL ABN97726.1 Transferase
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	nitrogen compound metabolic process Inferred from electronic annotation. Source: InterPro
Molecular function	[protein-PII] uridylyltransferase activity Inferred from electronic annotation. Source: HAMAP amino acid binding Inferred from electronic annotation. Source: InterPro metal ion binding Inferred from electronic annotation. Source: InterPro phosphoric diester hydrolase activity Inferred from electronic annotation. Source: InterPro
Complete GO annotation...

Sequences

	Sequence		Length	Mass (Da)
	A3PXU9 [UniParc]. Last modified April 3, 2007. Version 1. Checksum: 44140F9EF9F816E3	FASTA	837	89,574
	10 20 30 40 50 60 MTQQQPGSRP DPAAGAPRWT APAAGSARPA TDLVKATQQL LNGGPRPLDT AALRDALLDL 70 80 90 100 110 120 YEFWLGTKAN EIGITATSGF AIVATGGLGR GEMLPYSDLD LMLLHDNMPA DVVSQVAELL 130 140 150 160 170 180 WYPLWDANIR LDHSVRTVPE ALKVAGDDIS AGLAMLEVRH IAGDADLSNL LVGGARRQWR 190 200 210 220 230 240 TGIAPRFGEL VEHTQARWNR SGEIAHRAEP DLKSGRGGLR DVQLLNALAI AQLADVYPSP 250 260 270 280 290 300 ALASPTGTLG GAHLALLNVR TELHRVSGRG RDLLLAQYAD EIGAALRIGD RFDLARMLSD 310 320 330 340 350 360 AARTISYYVD AGLRTASNAL PRRGFAALRR PVRRPLDEGV VEYAGEVILA RDARPERDPG 370 380 390 400 410 420 LILRVAAASA TTGLPMAVST LSRLAETAPE LRTPWPREAL KDLLVMLGAG PAVVSTIEAL 430 440 450 460 470 480 DRTGLWGRLF PEWGAVRDLP PRDVVHIWTV DRHSVETVSR ASAFTTRVAR PDLLVLGALC 490 500 510 520 530 540 HDIGKGRGGD HSVIGAELAE QIGTRLGLWP SDIDLLSKMV RYHLLLPDTA TRRDLQDAKT 550 560 570 580 590 600 IDGVVDKLGG DLVLLELMHA LAEADSLATG PGVWGDWKAS LIGDLVRRCR LVMAGEPLPH 610 620 630 640 650 660 PDPIDPRHLE LAAEVGVHVE LTPSDSPHIH QVTMIAPDRR GLLSKAAGVL ALNSLRVHSA 670 680 690 700 710 720 SVNSHQGSAI NTFVVSPHFG APPAAGLLRQ QFMLALDGEL DVLAAVERRE REAAQYGTSR 730 740 750 760 770 780 AGEILAAVPA NHVPAPPRVL WSSGPSPSEV VVQIRTIDRV GLLARLTAVF ERDGVDIAWA 790 800 810 820 830 KVTTLGSSVV DVFGIAVPAL ATGTDADRQS IRAELERDLY AVLPTPPPPP KPAEQAS

References

[1]

"Complete sequence of Mycobacterium sp. JLS." Copeland A., Lucas S., Lapidus A., Barry K., Detter J.C., Glavina del Rio T., Hammon N., Israni S., Dalin E., Tice H., Pitluck S., Chain P., Malfatti S., Shin M., Vergez L., Schmutz J., Larimer F., Land M. , Hauser L., Kyrpides N., Mikhailova N., Miller C.D., Anderson A.J., Sims R.C., Richardson P. Submitted (FEB-2007) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: JLS.

Cross-references

Sequence databases
EMBL GenBank DDBJ	CP000580 Genomic DNA. Translation: ABN97726.1.
RefSeq	YP_001070217.1. NC_009077.1.
3D structure databases
ProteinModelPortal	A3PXU9.
ModBase	Search...
Protein-protein interaction databases
STRING	A3PXU9.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
EnsemblBacteria	EBMYCT00000048616; EBMYCP00000046897; EBMYCG00000048611.
GeneID	4877660.
GenomeReviews	Gene locus Mjls_1938 in contig CP000580_GR.
KEGG	mjl:Mjls_1938.
PATRIC	18089998. VBIMycSp51234_1939.
Organism-specific databases
CMR	Search...
Phylogenomic databases
eggNOG	COG2844.
GeneTree	EBGT00050000017408.
HOGENOM	HBG350889.
OMA	LPHTATR.
PhylomeDB	A3PXU9.
ProtClustDB	PRK03381.
Family and domain databases
HAMAP	MF_00277. PII_uridylyl_transf. [Tree]
InterPro	IPR002912. ACT-bd. IPR010043. GlnD_Uridyltrans. IPR023279. HD. IPR003607. Metal-dep_PHydrolase_HD_dom. IPR006674. Metal-dep_PHydrolase_HD_sub. IPR002934. Nucleotidyltransferase. IPR013546. PII_UdlTrfase/GS_AdlTrfase. [Graphical view]
Gene3D	G3DSA:1.10.3210.10. HD. 1 hit.
KO	K00990.
PANTHER	PTHR13734:SF1. GlnD_Uridyltrans. 1 hit.
Pfam	PF01842. ACT. 1 hit. PF08335. GlnD_UR_UTase. 1 hit. PF01966. HD. 1 hit. PF01909. NTP_transf_2. 1 hit. [Graphical view]
PIRSF	PIRSF006288. PII_uridyltransf. 1 hit.
SMART	SM00471. HDc. 1 hit. [Graphical view]
TIGRFAMs	TIGR01693. UTase_glnD. 1 hit.
ProtoNet	Search...

Entry information

Entry name

A3PXU9_MYCSJ

Accession

Primary (citable) accession number: A3PXU9

Entry history

Integrated into UniProtKB/TrEMBL:	April 3, 2007
Last sequence update:	April 3, 2007
Last modified:	December 14, 2011
This is version 39 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)