Skip Header

Contribute Send feedback
Read comments (?) or add your own

A3PVW1 (A3PVW1_MYCSJ) Unreviewed, UniProtKB/TrEMBL

Last modified May 1, 2013. Version 41. Feed History...

Clusters with 100%, 90%, 50% identity | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry infoCustomize order
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry infoCustomize order

Names and origin

Protein namesSubmitted name:
Isocitrate dehydrogenase, NADP-dependent EMBL ABN97038.1
EC=1.1.1.42 EMBL ABN97038.1
Gene names
Ordered Locus Names:Mjls_1236
OrganismMycobacterium sp. (strain JLS) [Complete proteome] [HAMAP] EMBL ABN97038.1
Taxonomic identifier164757 [NCBI]
Taxonomic lineageBacteria › Actinobacteria › Actinobacteridae › Actinomycetales › Corynebacterineae › Mycobacteriaceae › Mycobacterium

Protein attributes

Sequence length745 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Cofactor

Binds 1 magnesium or manganese ion per subunit By similarity. PIRSR PIRSR009407-3

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Regions

Region134 – 1418Substrate binding By similarity PIRSR PIRSR009407-2

Sites

Metal binding3521Magnesium or manganese By similarity PIRSR PIRSR009407-3
Metal binding5511Magnesium or manganese By similarity PIRSR PIRSR009407-3
Metal binding5551Magnesium or manganese By similarity PIRSR PIRSR009407-3
Binding site1471Substrate By similarity PIRSR PIRSR009407-2
Binding site5501Substrate By similarity PIRSR PIRSR009407-2
Site2571Critical for catalysis By similarity PIRSR PIRSR009407-1
Site4221Critical for catalysis By similarity PIRSR PIRSR009407-1

Sequences

Sequence LengthMass (Da)Tools
A3PVW1 [UniParc].

Last modified April 3, 2007. Version 1.
Checksum: 11E56C31138AFB75

FASTA74582,886
        10         20         30         40         50         60 
MSAEQPTIIY TLTDEAPLLA TYGFLPIIRT FAGAAGINVE TSDISVAARI LGEFNDRLPE 

        70         80         90        100        110        120 
DQRVPDNLAK LGELTQDPAT NIIKLPNISA SVPQLLAAIK ELKAKGYDLP DYPGDPKTDE 

       130        140        150        160        170        180 
EKENRARYEK VLGSAVNPVL RQGNSDRRAP KAVKEYAKKH PHSMGEWSMA SRTHVATMRH 

       190        200        210        220        230        240 
GDFYHGEKSM TIDRDRKVKM VLETKSGETI VLKPEVKLDE GDIIDSMFMS KKALCEFYEA 

       250        260        270        280        290        300 
QMQDAYETGV MFSLHVKATM MKVSHPIVFG HAVKVFYKDA FAKHQKLFDE LGVNVNNGMS 

       310        320        330        340        350        360 
DLYSKIEALP ASQREEIIND IHACHETRPE LAMVDSARGI TNFHSPSDVI VDASMPAMIR 

       370        380        390        400        410        420 
LGGKMYGADG RTKDTKAVNP ESTFSRMYQE MINWCKTNGQ FDPTTMGTVP NVGLMAQKAE 

       430        440        450        460        470        480 
EYGSHDKTFE IPEDGVANIV DIDTDEVLLT QNVEEGDIWR MPIVKDAPIR DWVKLAVTRA 

       490        500        510        520        530        540 
RASGMTAVFW LDTERPHEAE LRKKVKEYLK DHDTEGLHIQ IMPQVWAMRY TLERVTRGQD 

       550        560        570        580        590        600 
TIAVTGNILR DYLTDLFPIL ELGTSAKMLS IVPLMAGGGM YETGAGGSAP KHVHQLIEEN 

       610        620        630        640        650        660 
HLRWDSLGEF LALGACFEDL GRKTDNKRAA LLGKTMDAAI GKLLDNDKGP SRKTGELDNR 

       670        680        690        700        710        720 
GSQFYLAMYW AQELAGQTED KELAEHFAPL AEALVKNEET IVKELAAEQG KSVDIGGYYY 

       730        740 
PDSEKTTAVM RPSKTLNETL ESASV

« Hide

References

[1]"Complete sequence of Mycobacterium sp. JLS."
US DOE Joint Genome Institute
Copeland A., Lucas S., Lapidus A., Barry K., Detter J.C., Glavina del Rio T., Hammon N., Israni S., Dalin E., Tice H., Pitluck S., Chain P., Malfatti S., Shin M., Vergez L., Schmutz J., Larimer F., Land M. expand/collapse author list , Hauser L., Kyrpides N., Mikhailova N., Miller C.D., Anderson A.J., Sims R.C., Richardson P.
Submitted (FEB-2007) to the EMBL/GenBank/DDBJ databases
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: JLS.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ		CP000580 Genomic DNA. Translation: ABN97038.1.
RefSeqYP_001069529.1. NC_009077.1.

3D structure databases

ProteinModelPortalA3PVW1.
SMRA3PVW1. Positions 6-740.
ModBaseSearch...

Protein-protein interaction databases

STRING164757.Mjls_1236.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaABN97038; ABN97038; Mjls_1236.
GeneID4876972.
KEGGmjl:Mjls_1236.
PATRIC18088590. VBIMycSp51234_1239.

Organism-specific databases

CMRSearch...

Phylogenomic databases

eggNOGCOG2838.
HOGENOMHOG000240860.
KOK00031.
OMAPRTMGTV.
ProtClustDBCLSK867411.

Enzyme and pathway databases

BioCycMSP164757:GHV3-1291-MONOMER.

Family and domain databases

Gene3D3.40.718.10. 3 hits.
InterProIPR004436. Isocitrate_DH_NADP_mono.
IPR024084. IsoPropMal-DH-like_dom.
[Graphical view]
PfamPF03971. IDH. 1 hit.
[Graphical view]
PIRSFPIRSF009407. IDH_monmr. 1 hit.
TIGRFAMsTIGR00178. monomer_idh. 1 hit.
ProtoNetSearch...

Entry information

Entry nameA3PVW1_MYCSJ
AccessionPrimary (citable) accession number: A3PVW1
Entry history
Integrated into UniProtKB/TrEMBL: April 3, 2007
Last sequence update: April 3, 2007
Last modified: May 1, 2013
This is version 41 of the entry and version 1 of the sequence. [Complete history]
Entry statusUnreviewed (UniProtKB/TrEMBL)
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info