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A3PVP9 (A3PVP9_MYCSJ) Unreviewed, UniProtKB/TrEMBL

Last modified January 25, 2012. Version 40. Feed History...

Clusters with 100%, 90%, 50% identity | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein namesRecommended name:
Alanine racemase HAMAP MF_01201
EC=5.1.1.1 HAMAP MF_01201
Gene names
Name:alr HAMAP MF_01201
Ordered Locus Names:Mjls_1173
OrganismMycobacterium sp. (strain JLS) [Complete proteome] [HAMAP]
Taxonomic identifier164757 [NCBI]
Taxonomic lineageBacteria › Actinobacteria › Actinobacteridae › Actinomycetales › Corynebacterineae › Mycobacteriaceae › Mycobacterium

Protein attributes

Sequence length383 AA.
Sequence statusComplete.
Sequence processingThe displayed sequence is further processed into a mature form.
Protein existenceInferred from homology

General annotation (Comments)

Function

Provides the D-alanine required for cell wall biosynthesis By similarity. HAMAP MF_01201

Catalytic activity

L-alanine = D-alanine. HAMAP MF_01201

Cofactor

Pyridoxal phosphate By similarity. HAMAP MF_01201 SAAS SAAS009006

Pathway

Amino-acid biosynthesis; D-alanine biosynthesis; D-alanine from L-alanine: step 1/1. HAMAP MF_01201

Cell wall biogenesis; peptidoglycan biosynthesis. HAMAP MF_01201

Sequence similarities

Belongs to the alanine racemase family. HAMAP MF_01201 RuleBase RU004188

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Sites

Active site421Proton acceptor; specific for D-alanine By similarity HAMAP MF_01201
Active site2711Proton acceptor; specific for L-alanine By similarity HAMAP MF_01201

Amino acid modifications

Modified residue421N6-(pyridoxal phosphate)lysine By similarity HAMAP MF_01201

Sequences

Sequence LengthMass (Da)Tools
A3PVP9 [UniParc].

Last modified April 3, 2007. Version 1.
Checksum: 15FE4CBBB7D4C283

FASTA38340,596
        10         20         30         40         50         60 
MQTSETTVTP TAQVVVDLDA ISHNVALLRD RAGSAQVMPV LKADGYGHGA TEVAKVVLDA 

        70         80         90        100        110        120 
GVTELGVATV GEALALRADG ITAPVLAWLH GPGTDFAPAV QADIQLAVSS VRQLGEILDA 

       130        140        150        160        170        180 
VHRTGMTATL TVKADTGLSR NGVSPAEYPA LLQRLAKAQA EDAVRVRGIM SHLACGDEPD 

       190        200        210        220        230        240 
NPTNDRQAQR LTDMRRQAAD AGVTFEVAHL CNSPAAMTRP DLAFDMVRPG IAVYGQTPIP 

       250        260        270        280        290        300 
ALGDMGLRPA MTLRCPVAQT RSIKAGDGVS YGHTWIAQRD TTVALLPIGY ADGVYRSLSG 

       310        320        330        340        350        360 
RLQVLINGRL RPGVGRICMD QFVVDLGPGP VDVSDGDEAI LFGPGTRGEH TAQDWAEIIG 

       370        380 
TINYEIVTSP RGRVVRTYRR ESR

« Hide

References

[1]"Complete sequence of Mycobacterium sp. JLS."
Copeland A., Lucas S., Lapidus A., Barry K., Detter J.C., Glavina del Rio T., Hammon N., Israni S., Dalin E., Tice H., Pitluck S., Chain P., Malfatti S., Shin M., Vergez L., Schmutz J., Larimer F., Land M. expand/collapse author list , Hauser L., Kyrpides N., Mikhailova N., Miller C.D., Anderson A.J., Sims R.C., Richardson P.
Submitted (FEB-2007) to the EMBL/GenBank/DDBJ databases
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: JLS.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ		CP000580 Genomic DNA. Translation: ABN96976.1.
RefSeqYP_001069467.1. NC_009077.1.

3D structure databases

ProteinModelPortalA3PVP9.
SMRA3PVP9. Positions 12-379.
ModBaseSearch...

Protein-protein interaction databases

STRINGA3PVP9.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaEBMYCT00000053059; EBMYCP00000051340; EBMYCG00000053054.
GeneID4876910.
GenomeReviewsGene locus Mjls_1173 in contig CP000580_GR.
KEGGmjl:Mjls_1173.
PATRIC18088464. VBIMycSp51234_1176.

Organism-specific databases

CMRSearch...

Phylogenomic databases

eggNOGCOG0787.
GeneTreeEBGT00050000016627.
HOGENOMHBG712172.
OMAEGTPVWV.
PhylomeDBA3PVP9.
ProtClustDBPRK00053.

Family and domain databases

HAMAPMF_01201. Ala_racemase.
[Tree]
InterProIPR000821. Ala_racemase.
IPR009006. Ala_racemase/Decarboxylase_C.
IPR011079. Ala_racemase_C.
IPR001608. Ala_racemase_N.
[Graphical view]
Gene3DG3DSA:2.40.37.10. Ala_racemase/Decarboxylase_C. 1 hit.
KOK01775.
PfamPF00842. Ala_racemase_C. 1 hit.
PF01168. Ala_racemase_N. 1 hit.
[Graphical view]
PRINTSPR00992. ALARACEMASE.
SMARTSM01005. Ala_racemase_C. 1 hit.
[Graphical view]
SUPFAMSSF50621. Racem_decarbox_C. 1 hit.
TIGRFAMsTIGR00492. Alr. 1 hit.
ProtoNetSearch...

Entry information

Entry nameA3PVP9_MYCSJ
AccessionPrimary (citable) accession number: A3PVP9
Entry history
Integrated into UniProtKB/TrEMBL: April 3, 2007
Last sequence update: April 3, 2007
Last modified: January 25, 2012
This is version 40 of the entry and version 1 of the sequence. [Complete history]
Entry statusUnreviewed (UniProtKB/TrEMBL)
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