A3PTK2 (DCD_MYCSJ) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
Deoxycytidine triphosphate deaminase
Short name=dCTP deaminase
EC=3.5.4.13

Gene names

Name:	dcd
Ordered Locus Names:	Mjls_0417

Organism

Mycobacterium sp. (strain JLS) [Complete proteome] [HAMAP]

Taxonomic identifier

164757 [NCBI]

Taxonomic lineage

Bacteria › Actinobacteria › Actinobacteridae › Actinomycetales › Corynebacterineae › Mycobacteriaceae › Mycobacterium

Protein attributes

Sequence length	190 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Catalytic activity	dCTP + H2O = dUTP + NH3. HAMAP MF_00146
Pathway	Pyrimidine metabolism; dUMP biosynthesis; dUMP from dCTP (dUTP route): step 1/2. HAMAP MF_00146
Sequence similarities	Belongs to the dCTP deaminase family.

Ontologies

Keywords
Biological process	Nucleotide metabolism
Molecular function	Hydrolase
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	dUTP biosynthetic process Inferred from electronic annotation. Source: InterPro
Molecular function	dCTP deaminase activity Inferred from electronic annotation. Source: EC
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 190	190	Deoxycytidine triphosphate deaminase HAMAP MF_00146		PRO_1000009760

Sequences

	Sequence		Length	Mass (Da)
	A3PTK2 [UniParc]. Last modified April 3, 2007. Version 1. Checksum: 2DB1851580115598	FASTA	190	20,715
	10 20 30 40 50 60 MLLSDRDIRA EIDAGRLGID PFEDSLVQPS SVDVRLDTLF RVFNNTRYTH IDPAKQQDEL 70 80 90 100 110 120 TSLVEPSPGE PFVLHPGEFV LGSTLETCTL PDDLAGRLEG KSSLGRLGLL THSTAGFIDP 130 140 150 160 170 180 GFSGHITLEL SNVANLPITL WPGMKIGQLC LLRLTSPAEH PYGSAKVGSK YQGQRGPTPS 190 RSYQNFIKLS

References

[1]

"Complete sequence of Mycobacterium sp. JLS." US DOE Joint Genome Institute Copeland A., Lucas S., Lapidus A., Barry K., Detter J.C., Glavina del Rio T., Hammon N., Israni S., Dalin E., Tice H., Pitluck S., Chain P., Malfatti S., Shin M., Vergez L., Schmutz J., Larimer F., Land M. , Hauser L., Kyrpides N., Mikhailova N., Miller C.D., Anderson A.J., Sims R.C., Richardson P. Submitted (FEB-2007) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: JLS.

Cross-references

Sequence databases
EMBL GenBank DDBJ	CP000580 Genomic DNA. Translation: ABN96229.1.
RefSeq	YP_001068720.1. NC_009077.1.
3D structure databases
ProteinModelPortal	A3PTK2.
SMR	A3PTK2. Positions 1-188.
ModBase	Search...
Protein-protein interaction databases
STRING	A3PTK2.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
EnsemblBacteria	EBMYCT00000048617; EBMYCP00000046898; EBMYCG00000048612.
GeneID	4881491.
GenomeReviews	Gene locus Mjls_0417 in contig CP000580_GR.
KEGG	mjl:Mjls_0417.
PATRIC	18086951. VBIMycSp51234_0424.
Organism-specific databases
CMR	Search...
Phylogenomic databases
eggNOG	COG0717.
GeneTree	EBGT00050000016475.
HOGENOM	HBG553199.
OMA	HTAAYID.
PhylomeDB	A3PTK2.
ProtClustDB	PRK00416.
Enzyme and pathway databases
BioCyc	MSP164757:MJLS_0417-MONOMER.
Family and domain databases
HAMAP	MF_00146. dCTP_deaminase. [Tree]
InterPro	IPR011962. dCTP_deam. IPR008180. dUTP_pyroPase. [Graphical view]
KO	K01494.
Pfam	PF00692. dUTPase. 1 hit. [Graphical view]
TIGRFAMs	TIGR02274. DCTP_deam. 1 hit.
ProtoNet	Search...

Entry information

Entry name

DCD_MYCSJ

Accession

Primary (citable) accession number: A3PTK2

Entry history

Integrated into UniProtKB/Swiss-Prot:	January 15, 2008
Last sequence update:	April 3, 2007
Last modified:	January 25, 2012
This is version 33 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Prokaryotic Protein Annotation Program