Skip Header

Contribute Send feedback
Read comments (?) or add your own

A3PRF6 (DADA_RHOS1) Reviewed, UniProtKB/Swiss-Prot

Last modified December 14, 2011. Version 32. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
D-amino acid dehydrogenase small subunit
EC=1.4.99.1
Gene names
Name:dadA
Ordered Locus Names:Rsph17029_3842
OrganismRhodobacter sphaeroides (strain ATCC 17029 / ATH 2.4.9) [Complete proteome] [HAMAP]
Taxonomic identifier349101 [NCBI]
Taxonomic lineageBacteria › Proteobacteria › Alphaproteobacteria › Rhodobacterales › Rhodobacteraceae › Rhodobacter

Protein attributes

Sequence length436 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

Oxidative deamination of D-amino acids By similarity. HAMAP MF_01202

Catalytic activity

A D-amino acid + H2O + acceptor = a 2-oxo acid + NH3 + reduced acceptor. HAMAP MF_01202

Cofactor

FAD By similarity. HAMAP MF_01202

Pathway

Amino-acid degradation; D-alanine degradation; NH(3) and pyruvate from D-alanine: step 1/1. HAMAP MF_01202

Subunit structure

Heterodimer of a small and a large subunit By similarity.

Sequence similarities

Belongs to the DadA oxidoreductase family.

Ontologies

Keywords
   LigandFAD
Flavoprotein
   Molecular functionOxidoreductase
   Technical termComplete proteome
Gene Ontology (GO)
   Molecular functionD-amino-acid dehydrogenase activity

Inferred from electronic annotation. Source: EC

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 436436D-amino acid dehydrogenase small subunit HAMAP MF_01202
PRO_1000066111

Regions

Nucleotide binding3 – 1715FAD Potential

Sequences

Sequence LengthMass (Da)Tools
A3PRF6 [UniParc].

Last modified April 3, 2007. Version 1.
Checksum: 9989AA6E8528FBD1

FASTA43646,277
        10         20         30         40         50         60 
MRIVVLGAGV VGVTSAYELA RAGHEVTVVD RQPAAALETS FANAGEISPG YASPWAAPGI 

        70         80         90        100        110        120 
PAKALRWMFM KHAPLVIRPR LDAAQVRFLL AILRNCTPAA YAQNKGRMVR LAEYSRDCLT 

       130        140        150        160        170        180 
DLRATTGLAF DERQQGTLQL FRSQKQLDAA ARDIEVLRAG GVPFELLDAD GCLAAEPGLR 

       190        200        210        220        230        240 
AARDRIAGGL RLTGDETGDC FKFTQGLAGL AEEGGVRFRY GTGVERLRVE GGRVTGVETT 

       250        260        270        280        290        300 
KGTFLADAVV VALGSYSPAL VAPLGLRLPV YPVKGYSITV PIVDAERAPV STVMDETYKI 

       310        320        330        340        350        360 
AITRLGTRIR VGGMAEVAGF SATLPPARRE TLAMSVNDLF GGAGDLSRAS FWTGLRPMTP 

       370        380        390        400        410        420 
DGTPVVGRTP VAGLWLNTGH GTLGWTMAAG SARVLSDLID GRAPEIESAD LGIERYVAPD 

       430 
RRARPAVRLN PARQAG

« Hide

References

[1]"Complete sequence of chromosome 2 of Rhodobacter sphaeroides ATCC 17029."
Copeland A., Lucas S., Lapidus A., Barry K., Detter J.C., Glavina del Rio T., Hammon N., Israni S., Dalin E., Tice H., Pitluck S., Kiss H., Brettin T., Bruce D., Han C., Tapia R., Gilna P., Schmutz J. expand/collapse author list , Larimer F., Land M., Hauser L., Kyrpides N., Mikhailova N., Richardson P., Mackenzie C., Choudhary M., Donohue T.J., Kaplan S.
Submitted (FEB-2007) to the EMBL/GenBank/DDBJ databases
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: ATCC 17029 / ATH 2.4.9.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ		CP000578 Genomic DNA. Translation: ABN78922.1.
RefSeqYP_001045694.1. NC_009050.1.

3D structure databases

ProteinModelPortalA3PRF6.
ModBaseSearch...

Protein-protein interaction databases

STRINGA3PRF6.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

GeneID4898108.
GenomeReviewsGene locus Rsph17029_3842 in contig CP000578_GR.
KEGGrsh:Rsph17029_3842.
PATRIC23175713. VBIRhoSph114483_4118.

Organism-specific databases

CMRSearch...

Phylogenomic databases

eggNOGCOG0665.
HOGENOMHBG729204.
OMAVDRQPAV.
ProtClustDBPRK00711.

Enzyme and pathway databases

BioCycRSPH349101:RSPH17029_3842-MONOMER.

Family and domain databases

HAMAPMF_01202. DadA.
[Tree]
InterProIPR023080. D-aa_DH_ssu_DadA.
IPR006076. FAD-dep_OxRdtase.
[Graphical view]
KOK00285.
PfamPF01266. DAO. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameDADA_RHOS1
AccessionPrimary (citable) accession number: A3PRF6
Entry history
Integrated into UniProtKB/Swiss-Prot: February 5, 2008
Last sequence update: April 3, 2007
Last modified: December 14, 2011
This is version 32 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

PATHWAY comments

Index of metabolic and biosynthesis pathways

SIMILARITY comments

Index of protein domains and families

to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·Documents