Reviewed, UniProtKB/Swiss-Prot A3PRF6 (DADA_RHOS1)

Names and origin

Protein names

Recommended name:
    D-amino acid dehydrogenase small subunit
    EC=1.4.99.1

Gene names

Name:	dadA
Ordered Locus Names:	Rsph17029_3842

Organism

Rhodobacter sphaeroides (strain ATCC 17029 / ATH 2.4.9) [Complete proteome] [HAMAP]

Taxonomic identifier

349101 [NCBI]

Taxonomic lineage

Bacteria › Proteobacteria › Alphaproteobacteria › Rhodobacterales › Rhodobacteraceae › Rhodobacter

Protein attributes

Sequence length	436 AA.
Sequence status	Complete.
Sequence processing	The displayed sequence is not processed.
Protein existence	Inferred from homology.

General annotation (Comments)

Function	Oxidative deamination of D-amino acids By similarity.
Catalytic activity	A D-amino acid + H2O + acceptor = a 2-oxo acid + NH3 + reduced acceptor. HAMAP MF_01202
Cofactor	FAD By similarity.
Pathway	Amino-acid degradation; D-alanine degradation; NH(3) and pyruvate from D-alanine: step 1/1. HAMAP MF_01202
Subunit structure	Heterodimer of a small and a large subunit By similarity.
Sequence similarities	Belongs to the dadA oxidoreductase family.

Ontologies

Keywords
Ligand	FAD Flavoprotein
Molecular function	Oxidoreductase
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	alanine catabolic process Inferred from electronic annotation. Source: HAMAP oxidation reduction Inferred from electronic annotation. Source: UniProtKB-KW
Molecular function	D-amino-acid dehydrogenase activity Inferred from electronic annotation. Source: HAMAP
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 436	436	D-amino acid dehydrogenase small subunit HAMAP MF_01202		PRO_1000066111
Regions
	Nucleotide binding	3 – 17	15	FAD Potential

Sequences

	Sequence		Length	Mass (Da)
	A3PRF6-1 [UniParc]. Last modified April 3, 2007. Version 1. Checksum: 9989AA6E8528FBD1	FASTA	436	46,277
	10 20 30 40 50 60 MRIVVLGAGV VGVTSAYELA RAGHEVTVVD RQPAAALETS FANAGEISPG YASPWAAPGI 70 80 90 100 110 120 PAKALRWMFM KHAPLVIRPR LDAAQVRFLL AILRNCTPAA YAQNKGRMVR LAEYSRDCLT 130 140 150 160 170 180 DLRATTGLAF DERQQGTLQL FRSQKQLDAA ARDIEVLRAG GVPFELLDAD GCLAAEPGLR 190 200 210 220 230 240 AARDRIAGGL RLTGDETGDC FKFTQGLAGL AEEGGVRFRY GTGVERLRVE GGRVTGVETT 250 260 270 280 290 300 KGTFLADAVV VALGSYSPAL VAPLGLRLPV YPVKGYSITV PIVDAERAPV STVMDETYKI 310 320 330 340 350 360 AITRLGTRIR VGGMAEVAGF SATLPPARRE TLAMSVNDLF GGAGDLSRAS FWTGLRPMTP 370 380 390 400 410 420 DGTPVVGRTP VAGLWLNTGH GTLGWTMAAG SARVLSDLID GRAPEIESAD LGIERYVAPD 430 RRARPAVRLN PARQAG

References

[1]

"Complete sequence of chromosome 2 of Rhodobacter sphaeroides ATCC 17029." Copeland A., Lucas S., Lapidus A., Barry K., Detter J.C., Glavina del Rio T., Hammon N., Israni S., Dalin E., Tice H., Pitluck S., Kiss H., Brettin T., Bruce D., Han C., Tapia R., Gilna P., Schmutz J. , Larimer F., Land M., Hauser L., Kyrpides N., Mikhailova N., Richardson P., Mackenzie C., Choudhary M., Donohue T.J., Kaplan S. Submitted (FEB-2007) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].

Cross-references

Sequence databases
EMBLGenBankDDBJ	CP000578 Genomic DNA. Translation: ABN78922.1.
RefSeq	YP_001045694.1.
3D structure databases
ModBase	Search...
Genome annotation databases
GeneID	4898108.
GenomeReviews	Gene locus Rsph17029_3842 in contig CP000578_GR.
KEGG	rsh:Rsph17029_3842.
Organism-specific databases
CMR	Search...
Phylogenomic databases
OMA	A3PRF6. MFQKHAP.
Family and domain databases
HAMAP	MF_01202. [Tree]
InterPro	IPR006076. FAD-dep_OxRdtase. [Graphical view]
Pfam	PF01266. DAO. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

DADA_RHOS1

Accession

Primary (citable) accession number: A3PRF6

Entry history

Integrated into UniProtKB/Swiss-Prot:	February 5, 2008
Last sequence update:	April 3, 2007
Last modified:	June 16, 2009
This is version 14 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation project

HAMAP (High-quality Automated and Manual Annotation of microbial Proteomes)